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Resistance (weight lifting) training in an adolescent with McArdle disease

Resistance (weight lifting) training in an adolescent with McArdle disease

Garcia-Benitez, Sergio, Fleck, Steven J., Naclerio, Fernando ORCID: 0000-0001-7405-4894, Martin, Miguel Angel and Lucia, Alejandro (2013) Resistance (weight lifting) training in an adolescent with McArdle disease. Journal of Child Neurology, 28 (6). pp. 805-808. ISSN 0883-0738 (Print), 1708-8283 (Online) (doi:

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Owing to the risk of severe rhabdomyolysis, clinicians advise McArdle disease patients to refrain from strenuous exercise, particularly weight lifting. A 15-year-old male McArdle disease patient performed a 6-week, supervised, light- to moderate-intensity (∼65-70% of one-repetition-maximum) resistance (weight lifting) training program (2 sessions/week). Training resulted in ∼27% and ∼6% increase in one-repetition-maximum bench press and multipower squat performance while inducing no myoglobinuria. The patient changed to a lower disease severity class, that is, he became virtually asymptomatic in terms of exercise limitations. The authors’ preliminary data suggest that supervised, light to moderate resistance training is feasible in children with McArdle disease and has potential clinical benefits.

Item Type: Article
Additional Information: [1] Copyright: (c) The Author(s) 2012
Uncontrolled Keywords: glycogenosis, exercise, muscle damage, CK, McArdle disease
Subjects: Q Science > QP Physiology
Faculty / School / Research Centre / Research Group: Faculty of Engineering & Science
Faculty of Education, Health & Human Sciences > School of Human Sciences (HUM)
Last Modified: 09 Oct 2021 04:46

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