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Items where Author is "Male, Louise"

Items where Author is "Male, Louise"

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1′-dicarbaldehyde activation agents antimalarial antitumor-activity benzodiazepines biaryls bond boronic acid breast-cancer chemistry chloroquine complexes dbu design drugs estrogen-receptor modulators ferrocene-1 ferrocifens growth-factor receptor in-vitro Indolin-2-one (oxindole) inhibitors Knoevenagel condensation microwave microwave irradiation microwaves nucleophilic substitution organometallic chemistry palladium parallel synthesis pi interactions precatalysts reduction supported reagents Suzuki coupling trypanosoma tyrosine kinase-activity
Number of items: 39.

1′-dicarbaldehyde

Spencer, John, Nielsen, Birthe ORCID: 0000-0002-0849-4987 , Thomas, Michael J.K., Male, Louise and Coles, Simon J. (2011) The Knoevenagel product of indolin-2-one and ferrocene-1,1′-dicarbaldehyde. Acta Crystallographica Section C, 67 (7). m245-m248. ISSN 0108-2701 (doi:https://doi.org/10.1107/S0108270111021536)

activation

Spencer, John, Mendham, Andrew P., Kotha, Arun K., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Hillard, Elizabeth A., Jaouen, Gérard, Male, Louise and Hursthouse, Michael B. (2008) Structural and biological investigation of ferrocene-substituted 3-methylidene-1,3-dihydro-2H-indol-2-ones. Dalton Transactions, 2009 (6). pp. 918-921. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:https://doi.org/10.1039/B816249B)

agents

Spencer, John, Rathnam, Rajendra P., Montukuri, Mahesh, Kotha, Arun K., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Hazrati, Ali, Hartley, John A., Male, Louise and Hursthouse, Michael B. (2009) Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity. Dalton Transactions (22). pp. 4299-4303. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:https://doi.org/10.1039/b819061e)

antimalarial

Spencer, John, Mendham, Andrew P., Kotha, Arun K., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Hillard, Elizabeth A., Jaouen, Gérard, Male, Louise and Hursthouse, Michael B. (2008) Structural and biological investigation of ferrocene-substituted 3-methylidene-1,3-dihydro-2H-indol-2-ones. Dalton Transactions, 2009 (6). pp. 918-921. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:https://doi.org/10.1039/B816249B)

antitumor-activity

Spencer, John, Rathnam, Rajendra P., Montukuri, Mahesh, Kotha, Arun K., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Hazrati, Ali, Hartley, John A., Male, Louise and Hursthouse, Michael B. (2009) Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity. Dalton Transactions (22). pp. 4299-4303. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:https://doi.org/10.1039/b819061e)

benzodiazepines

Spencer, John, Rathnam, Rajendra P., Harvey, Alan L., Clements, Carol J., Clark, Rachel L., Barrett, Michael P., Wong, Pui Ee, Male, Louise, Coles, Simon J. and Mackay, Simon P. (2011) Synthesis and biological evaluation of 1,4-benzodiazepin-2-ones with antitrypanosomal activity. Bioorganic & Medicinal Chemistry, 19 (5). pp. 1802-1815. ISSN 0968-0896 (doi:https://doi.org/10.1016/j.bmc.2011.01.010)

biaryls

Spencer, John, Baltus, Christine B., Patel, Hiren, Press, Neil J., Callear, Samantha K., Male, Louise and Coles, Simon J. (2010) Microwave-mediated synthesis of an arylboronate library. ACS Combinatorial Science, 2011 (13):1. pp. 24-31. ISSN 2156-8952 (Print), 2156-8944 (Online) (doi:https://doi.org/10.1021/co100011g)

bond

Spencer, John, Chowdhry, Babur Z., Hamid, Samiyah, Mendham, Andrew P., Male, Louise, Coles, Simon J. and Hursthouse, Michael B. (2010) Seven 3-methylidene-1H-indol-2(3H)-ones related to the multiple-receptor tyrosine kinase inhibitor sunitinib. Acta Crystallographica Section C: Crystal Structure Communications, 66 (2). o71-o78. ISSN 0108-2701 (Print), 1600-5759 (Online) (doi:https://doi.org/10.1107/S0108270109054134)

boronic acid

Spencer, John, Baltus, Christine B., Patel, Hiren, Press, Neil J., Callear, Samantha K., Male, Louise and Coles, Simon J. (2010) Microwave-mediated synthesis of an arylboronate library. ACS Combinatorial Science, 2011 (13):1. pp. 24-31. ISSN 2156-8952 (Print), 2156-8944 (Online) (doi:https://doi.org/10.1021/co100011g)

breast-cancer

Spencer, John, Mendham, Andrew P., Kotha, Arun K., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Hillard, Elizabeth A., Jaouen, Gérard, Male, Louise and Hursthouse, Michael B. (2008) Structural and biological investigation of ferrocene-substituted 3-methylidene-1,3-dihydro-2H-indol-2-ones. Dalton Transactions, 2009 (6). pp. 918-921. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:https://doi.org/10.1039/B816249B)

chemistry

Spencer, John, Mendham, Andrew P., Kotha, Arun K., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Hillard, Elizabeth A., Jaouen, Gérard, Male, Louise and Hursthouse, Michael B. (2008) Structural and biological investigation of ferrocene-substituted 3-methylidene-1,3-dihydro-2H-indol-2-ones. Dalton Transactions, 2009 (6). pp. 918-921. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:https://doi.org/10.1039/B816249B)

chloroquine

Spencer, John, Mendham, Andrew P., Kotha, Arun K., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Hillard, Elizabeth A., Jaouen, Gérard, Male, Louise and Hursthouse, Michael B. (2008) Structural and biological investigation of ferrocene-substituted 3-methylidene-1,3-dihydro-2H-indol-2-ones. Dalton Transactions, 2009 (6). pp. 918-921. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:https://doi.org/10.1039/B816249B)

complexes

Spencer, John, Rathnam, Rajendra P., Montukuri, Mahesh, Kotha, Arun K., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Hazrati, Ali, Hartley, John A., Male, Louise and Hursthouse, Michael B. (2009) Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity. Dalton Transactions (22). pp. 4299-4303. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:https://doi.org/10.1039/b819061e)

dbu

Spencer, John, Chowdhry, Babur Z., Hamid, Samiyah, Mendham, Andrew P., Male, Louise, Coles, Simon J. and Hursthouse, Michael B. (2010) Seven 3-methylidene-1H-indol-2(3H)-ones related to the multiple-receptor tyrosine kinase inhibitor sunitinib. Acta Crystallographica Section C: Crystal Structure Communications, 66 (2). o71-o78. ISSN 0108-2701 (Print), 1600-5759 (Online) (doi:https://doi.org/10.1107/S0108270109054134)

design

Spencer, John, Rathnam, Rajendra P., Montukuri, Mahesh, Kotha, Arun K., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Hazrati, Ali, Hartley, John A., Male, Louise and Hursthouse, Michael B. (2009) Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity. Dalton Transactions (22). pp. 4299-4303. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:https://doi.org/10.1039/b819061e)

drugs

Spencer, John, Rathnam, Rajendra P., Montukuri, Mahesh, Kotha, Arun K., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Hazrati, Ali, Hartley, John A., Male, Louise and Hursthouse, Michael B. (2009) Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity. Dalton Transactions (22). pp. 4299-4303. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:https://doi.org/10.1039/b819061e)

estrogen-receptor modulators

Spencer, John, Mendham, Andrew P., Kotha, Arun K., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Hillard, Elizabeth A., Jaouen, Gérard, Male, Louise and Hursthouse, Michael B. (2008) Structural and biological investigation of ferrocene-substituted 3-methylidene-1,3-dihydro-2H-indol-2-ones. Dalton Transactions, 2009 (6). pp. 918-921. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:https://doi.org/10.1039/B816249B)

ferrocene-1

Spencer, John, Nielsen, Birthe ORCID: 0000-0002-0849-4987 , Thomas, Michael J.K., Male, Louise and Coles, Simon J. (2011) The Knoevenagel product of indolin-2-one and ferrocene-1,1′-dicarbaldehyde. Acta Crystallographica Section C, 67 (7). m245-m248. ISSN 0108-2701 (doi:https://doi.org/10.1107/S0108270111021536)

ferrocifens

Spencer, John, Mendham, Andrew P., Kotha, Arun K., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Hillard, Elizabeth A., Jaouen, Gérard, Male, Louise and Hursthouse, Michael B. (2008) Structural and biological investigation of ferrocene-substituted 3-methylidene-1,3-dihydro-2H-indol-2-ones. Dalton Transactions, 2009 (6). pp. 918-921. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:https://doi.org/10.1039/B816249B)

growth-factor receptor

Spencer, John, Chowdhry, Babur Z., Hamid, Samiyah, Mendham, Andrew P., Male, Louise, Coles, Simon J. and Hursthouse, Michael B. (2010) Seven 3-methylidene-1H-indol-2(3H)-ones related to the multiple-receptor tyrosine kinase inhibitor sunitinib. Acta Crystallographica Section C: Crystal Structure Communications, 66 (2). o71-o78. ISSN 0108-2701 (Print), 1600-5759 (Online) (doi:https://doi.org/10.1107/S0108270109054134)

in-vitro

Spencer, John, Mendham, Andrew P., Kotha, Arun K., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Hillard, Elizabeth A., Jaouen, Gérard, Male, Louise and Hursthouse, Michael B. (2008) Structural and biological investigation of ferrocene-substituted 3-methylidene-1,3-dihydro-2H-indol-2-ones. Dalton Transactions, 2009 (6). pp. 918-921. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:https://doi.org/10.1039/B816249B)

Indolin-2-one (oxindole)

Spencer, John, Nielsen, Birthe ORCID: 0000-0002-0849-4987 , Thomas, Michael J.K., Male, Louise and Coles, Simon J. (2011) The Knoevenagel product of indolin-2-one and ferrocene-1,1′-dicarbaldehyde. Acta Crystallographica Section C, 67 (7). m245-m248. ISSN 0108-2701 (doi:https://doi.org/10.1107/S0108270111021536)

inhibitors

Spencer, John, Rathnam, Rajendra P., Montukuri, Mahesh, Kotha, Arun K., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Hazrati, Ali, Hartley, John A., Male, Louise and Hursthouse, Michael B. (2009) Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity. Dalton Transactions (22). pp. 4299-4303. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:https://doi.org/10.1039/b819061e)

Spencer, John, Mendham, Andrew P., Kotha, Arun K., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Hillard, Elizabeth A., Jaouen, Gérard, Male, Louise and Hursthouse, Michael B. (2008) Structural and biological investigation of ferrocene-substituted 3-methylidene-1,3-dihydro-2H-indol-2-ones. Dalton Transactions, 2009 (6). pp. 918-921. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:https://doi.org/10.1039/B816249B)

Knoevenagel condensation

Spencer, John, Nielsen, Birthe ORCID: 0000-0002-0849-4987 , Thomas, Michael J.K., Male, Louise and Coles, Simon J. (2011) The Knoevenagel product of indolin-2-one and ferrocene-1,1′-dicarbaldehyde. Acta Crystallographica Section C, 67 (7). m245-m248. ISSN 0108-2701 (doi:https://doi.org/10.1107/S0108270111021536)

microwave

Spencer, John, Baltus, Christine B., Patel, Hiren, Press, Neil J., Callear, Samantha K., Male, Louise and Coles, Simon J. (2010) Microwave-mediated synthesis of an arylboronate library. ACS Combinatorial Science, 2011 (13):1. pp. 24-31. ISSN 2156-8952 (Print), 2156-8944 (Online) (doi:https://doi.org/10.1021/co100011g)

microwave irradiation

Spencer, John, Chowdhry, Babur Z., Hamid, Samiyah, Mendham, Andrew P., Male, Louise, Coles, Simon J. and Hursthouse, Michael B. (2010) Seven 3-methylidene-1H-indol-2(3H)-ones related to the multiple-receptor tyrosine kinase inhibitor sunitinib. Acta Crystallographica Section C: Crystal Structure Communications, 66 (2). o71-o78. ISSN 0108-2701 (Print), 1600-5759 (Online) (doi:https://doi.org/10.1107/S0108270109054134)

microwaves

Spencer, John, Rathnam, Rajendra P., Harvey, Alan L., Clements, Carol J., Clark, Rachel L., Barrett, Michael P., Wong, Pui Ee, Male, Louise, Coles, Simon J. and Mackay, Simon P. (2011) Synthesis and biological evaluation of 1,4-benzodiazepin-2-ones with antitrypanosomal activity. Bioorganic & Medicinal Chemistry, 19 (5). pp. 1802-1815. ISSN 0968-0896 (doi:https://doi.org/10.1016/j.bmc.2011.01.010)

nucleophilic substitution

Spencer, John, Baltus, Christine B., Patel, Hiren, Press, Neil J., Callear, Samantha K., Male, Louise and Coles, Simon J. (2010) Microwave-mediated synthesis of an arylboronate library. ACS Combinatorial Science, 2011 (13):1. pp. 24-31. ISSN 2156-8952 (Print), 2156-8944 (Online) (doi:https://doi.org/10.1021/co100011g)

organometallic chemistry

Spencer, John, Rathnam, Rajendra P., Montukuri, Mahesh, Kotha, Arun K., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Hazrati, Ali, Hartley, John A., Male, Louise and Hursthouse, Michael B. (2009) Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity. Dalton Transactions (22). pp. 4299-4303. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:https://doi.org/10.1039/b819061e)

palladium

Spencer, John, Rathnam, Rajendra P., Montukuri, Mahesh, Kotha, Arun K., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Hazrati, Ali, Hartley, John A., Male, Louise and Hursthouse, Michael B. (2009) Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity. Dalton Transactions (22). pp. 4299-4303. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:https://doi.org/10.1039/b819061e)

parallel synthesis

Spencer, John, Rathnam, Rajendra P., Harvey, Alan L., Clements, Carol J., Clark, Rachel L., Barrett, Michael P., Wong, Pui Ee, Male, Louise, Coles, Simon J. and Mackay, Simon P. (2011) Synthesis and biological evaluation of 1,4-benzodiazepin-2-ones with antitrypanosomal activity. Bioorganic & Medicinal Chemistry, 19 (5). pp. 1802-1815. ISSN 0968-0896 (doi:https://doi.org/10.1016/j.bmc.2011.01.010)

pi interactions

Spencer, John, Chowdhry, Babur Z., Hamid, Samiyah, Mendham, Andrew P., Male, Louise, Coles, Simon J. and Hursthouse, Michael B. (2010) Seven 3-methylidene-1H-indol-2(3H)-ones related to the multiple-receptor tyrosine kinase inhibitor sunitinib. Acta Crystallographica Section C: Crystal Structure Communications, 66 (2). o71-o78. ISSN 0108-2701 (Print), 1600-5759 (Online) (doi:https://doi.org/10.1107/S0108270109054134)

precatalysts

Spencer, John, Rathnam, Rajendra P., Montukuri, Mahesh, Kotha, Arun K., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Hazrati, Ali, Hartley, John A., Male, Louise and Hursthouse, Michael B. (2009) Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity. Dalton Transactions (22). pp. 4299-4303. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:https://doi.org/10.1039/b819061e)

reduction

Spencer, John, Chowdhry, Babur Z., Hamid, Samiyah, Mendham, Andrew P., Male, Louise, Coles, Simon J. and Hursthouse, Michael B. (2010) Seven 3-methylidene-1H-indol-2(3H)-ones related to the multiple-receptor tyrosine kinase inhibitor sunitinib. Acta Crystallographica Section C: Crystal Structure Communications, 66 (2). o71-o78. ISSN 0108-2701 (Print), 1600-5759 (Online) (doi:https://doi.org/10.1107/S0108270109054134)

supported reagents

Spencer, John, Baltus, Christine B., Patel, Hiren, Press, Neil J., Callear, Samantha K., Male, Louise and Coles, Simon J. (2010) Microwave-mediated synthesis of an arylboronate library. ACS Combinatorial Science, 2011 (13):1. pp. 24-31. ISSN 2156-8952 (Print), 2156-8944 (Online) (doi:https://doi.org/10.1021/co100011g)

Suzuki coupling

Spencer, John, Baltus, Christine B., Patel, Hiren, Press, Neil J., Callear, Samantha K., Male, Louise and Coles, Simon J. (2010) Microwave-mediated synthesis of an arylboronate library. ACS Combinatorial Science, 2011 (13):1. pp. 24-31. ISSN 2156-8952 (Print), 2156-8944 (Online) (doi:https://doi.org/10.1021/co100011g)

trypanosoma

Spencer, John, Rathnam, Rajendra P., Harvey, Alan L., Clements, Carol J., Clark, Rachel L., Barrett, Michael P., Wong, Pui Ee, Male, Louise, Coles, Simon J. and Mackay, Simon P. (2011) Synthesis and biological evaluation of 1,4-benzodiazepin-2-ones with antitrypanosomal activity. Bioorganic & Medicinal Chemistry, 19 (5). pp. 1802-1815. ISSN 0968-0896 (doi:https://doi.org/10.1016/j.bmc.2011.01.010)

tyrosine kinase-activity

Spencer, John, Mendham, Andrew P., Kotha, Arun K., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Hillard, Elizabeth A., Jaouen, Gérard, Male, Louise and Hursthouse, Michael B. (2008) Structural and biological investigation of ferrocene-substituted 3-methylidene-1,3-dihydro-2H-indol-2-ones. Dalton Transactions, 2009 (6). pp. 918-921. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:https://doi.org/10.1039/B816249B)

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