Mills, Deanna, Ogunsanya, Olaide, Armitage, Andrew ORCID: https://orcid.org/0000-0002-0610-763X, Stevenson, Philip ORCID: https://orcid.org/0000-0002-0736-3619 and Harte, Steven ORCID: https://orcid.org/0000-0001-9628-7912 (2023) Mining the untapped chemical potential of entomopathogenic fungi. In: LIDo End of Rotation 1 Presentation Day, 17th Feb, 2023, Medical Sciences and Anatomy building, UCL.

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Abstract

• Given the immense fungal biodiversity (with an estimated 2.2 to 3.8 million species of fungi worldwide [1]) and broad range of fungal habitats, fungi are
one of the best sources of natural bioactive compounds, with huge industrial and medicinal potential.
• Entomopathogenic fungi (EPF) are fungi that infect and kill arthropods.
• EPF produce unique secondary metabolites and rapidly adjust their metabolic outputs in response to changes in environmental conditions. [2] These
metabolites are usually produced transiently, in low quantities or not at all under laboratory conditions.
• With the market for commercial EPF biopesticides growing considerably in recent years, EPF secondary metabolites present an understudied and
biotechnologically valuable opportunity for the pharmaceutical and agricultural industries.
PROJECT AIM: Develop liquid culturing techniques of EPF to optimise metabolite production that facilitates structural elucidation and biological activity testing.

Item Type:	Conference or Conference Paper (Poster)
Uncontrolled Keywords:	metabolites; entomopathogenic fungi; biopesticides; metabolomics; HPLC
Subjects:	Q Science > Q Science (General) S Agriculture > S Agriculture (General)
Faculty / School / Research Centre / Research Group:	Faculty of Engineering & Science > Natural Resources Institute > Chemical Ecology Research Group Faculty of Engineering & Science Faculty of Engineering & Science > Natural Resources Institute Faculty of Engineering & Science > Natural Resources Institute > Agriculture, Health & Environment Department Faculty of Engineering & Science > Natural Resources Institute > Centre for Sustainable Agriculture 4 One Health Faculty of Engineering & Science > Natural Resources Institute > Centre for Sustainable Agriculture 4 One Health > Molecular Virology & Entomology
Last Modified:	27 Nov 2024 15:18
URI:	http://gala.gre.ac.uk/id/eprint/45722

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