Rapid access to CF3 -containing heterocycles
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Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 , Parker, Robert J. and Skidmore, John (2007) Rapid access to CF3 -containing heterocycles. Tetrahedron Letters, 49 (5). pp. 827-831. ISSN 0040-4039 (doi:https://doi.org/10.1016/j.tetlet.2007.11.178)
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Official URL: http://dx.doi.org/10.1016/j.tetlet.2007.11.178
Abstract
The silyl-Prins and aza-silyl-Prins reactions have been employed for the preparation of 6-CF3-substituted dihydropyrans and 6-CF3-substituted tetrahydropyridines. The product heterocycles have been further elaborated to a number of products, including CF3-substituted pipecolates and hydroxylated pyrans and piperidines.
Item Type: | Article |
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Uncontrolled Keywords: | Silyl-Prins reaction, Aza-silyl-Prins reaction, 6-CF3-substituted dihydropyrans, 6-CF3-substituted tetrahydropyridines, Pipecolic acid derivatives |
Subjects: | Q Science > QD Chemistry |
Faculty / School / Research Centre / Research Group: | Faculty of Engineering & Science > School of Science (SCI) |
Related URLs: | |
Last Modified: | 21 Oct 2020 22:31 |
URI: | http://gala.gre.ac.uk/id/eprint/10576 |
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