Dobbs, Adrian P. ORCID: https://orcid.org/0000-0002-7241-7118, Parker, Robert J. and Skidmore, John (2007) Rapid access to CF3 -containing heterocycles. Tetrahedron Letters, 49 (5). pp. 827-831. ISSN 0040-4039 (doi:10.1016/j.tetlet.2007.11.178)

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Abstract

The silyl-Prins and aza-silyl-Prins reactions have been employed for the preparation of 6-CF3-substituted dihydropyrans and 6-CF3-substituted tetrahydropyridines. The product heterocycles have been further elaborated to a number of products, including CF3-substituted pipecolates and hydroxylated pyrans and piperidines.

Item Type:	Article
Uncontrolled Keywords:	Silyl-Prins reaction, Aza-silyl-Prins reaction, 6-CF3-substituted dihydropyrans, 6-CF3-substituted tetrahydropyridines, Pipecolic acid derivatives
Subjects:	Q Science > QD Chemistry
Faculty / School / Research Centre / Research Group:	Faculty of Engineering & Science > School of Science (SCI)
Related URLs:	Organisation
Last Modified:	21 Oct 2020 22:31
URI:	http://gala.gre.ac.uk/id/eprint/10576

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