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Preparation and optimization of PMAA-Chitosan-PEG nanoparticles for oral drug delivery

Preparation and optimization of PMAA-Chitosan-PEG nanoparticles for oral drug delivery

Pawar, H., Douroumis, D. and Boateng, J.S. ORCID: 0000-0002-6310-729X (2010) Preparation and optimization of PMAA-Chitosan-PEG nanoparticles for oral drug delivery. Journal of Pharmacy and Pharmacology, 62 (10). pp. 1463-1464. ISSN 2042-7158 (Print), 0022-3573 (Online) (doi:10.1111/j.2042-7158.2010.01178.x)

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Abstract

INTRODUCTION: In the current study pH sensitive polymethacrylic acid – chitosan–polyethyleneglycol (PCP) nanoparticles, were developed through a free radical polymerisation process [1]. Metoprolol was used as a model active substance and the obtained PCP nanoparticles presented excellent drug loading (20–30%) and bioadhesion properties.

Item Type: Article
Additional Information: [1] Abstract published in Journal of Pharmacy and Pharmacology, Volume 62, Issue 10, pages 1201–1516, October 2010 - Special Issue: UK-PharmSci 2010 - The Science of Medicines. Abstracts from the UK conference, 1-3 September 2010.
Uncontrolled Keywords: PMAA-Chitosan-PEG, nanoparticles, oral drug delivery, muco-adhesion
Subjects: R Medicine > RS Pharmacy and materia medica
Faculty / Department / Research Group: Faculty of Engineering & Science
Faculty of Engineering & Science > Department of Pharmaceutical, Chemical & Environmental Sciences
Related URLs:
Last Modified: 17 Oct 2016 09:12
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
URI: http://gala.gre.ac.uk/id/eprint/8279

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