Apolipoprotein H: Its relevance to cardiovascular disease
Crook, M.A. (2010) Apolipoprotein H: Its relevance to cardiovascular disease. Atherosclerosis, 209 (1). pp. 32-34. ISSN Volume 209, Issue 1, March 2010, Pages 32–34 (doi:10.1016/j.atherosclerosis.2009.11.022)Full text not available from this repository.
Apolipoprotein H (Apo H) is a single chain glycoprotein consisting of 326 amino acid residues with a molecular weight of about 50 kDa and is involved in clotting mechanisms and lipid pathways . Castro and colleagues report in this journal that plasma concentrations of Apo H are strongly associated with the metabolic syndrome and cardiovascular disease in type 2 diabetic patients and could be considered as a clinical marker of cardiovascular risk. The increased Apo H concentration in these patients was due to its increased liver synthesis. Apo H is attracting interest in the field of cardiovascular disease, diabetes mellitus, haemostasis and lipidology and may provide an exciting link between them but why is this?
|Uncontrolled Keywords:||apo H, diabetes mellitus, lipids, antiphospholipid antibody syndrome, cardiovascular disease, beta2-glycoprotein I|
|Subjects:||R Medicine > R Medicine (General)
R Medicine > RZ Other systems of medicine
|School / Department / Research Groups:||School of Science
Faculty of Engineering & Science > School of Science
|Last Modified:||21 Mar 2012 10:31|
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