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Apolipoprotein H: Its relevance to cardiovascular disease

Apolipoprotein H: Its relevance to cardiovascular disease

Crook, M.A. (2010) Apolipoprotein H: Its relevance to cardiovascular disease. Atherosclerosis, 209 (1). pp. 32-34. ISSN Volume 209, Issue 1, March 2010, Pages 32–34 (doi:10.1016/j.atherosclerosis.2009.11.022)

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Abstract

Apolipoprotein H (Apo H) is a single chain glycoprotein consisting of 326 amino acid residues with a molecular weight of about 50 kDa and is involved in clotting mechanisms and lipid pathways [1]. Castro and colleagues report in this journal that plasma concentrations of Apo H are strongly associated with the metabolic syndrome and cardiovascular disease in type 2 diabetic patients and could be considered as a clinical marker of cardiovascular risk. The increased Apo H concentration in these patients was due to its increased liver synthesis. Apo H is attracting interest in the field of cardiovascular disease, diabetes mellitus, haemostasis and lipidology and may provide an exciting link between them but why is this?

Item Type: Article
Uncontrolled Keywords: apo H, diabetes mellitus, lipids, antiphospholipid antibody syndrome, cardiovascular disease, beta2-glycoprotein I
Subjects: R Medicine > R Medicine (General)
R Medicine > RZ Other systems of medicine
Pre-2014 Departments: School of Science
Related URLs:
Last Modified: 14 Oct 2016 09:19
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
URI: http://gala.gre.ac.uk/id/eprint/7738

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