Paradoxical decrease in serum high-density lipoprotein cholesterol and lipid-lowering drugs
Crook, M.A. (2011) Paradoxical decrease in serum high-density lipoprotein cholesterol and lipid-lowering drugs. Annals of Clinical Biochemistry, 48 (1). pp. 3-4. ISSN 0004 5632 (doi:10.1258/acb.2010.010269)Full text not available from this repository.
The author reflects on the paradoxical decline in serum high-density lipoprotein cholesterol (HDL-c) concentration using simvastatin and atorvastatin. He discusses the role of cholesterol ester transfer protein on the esterification of free cholesterol and activation by apolipoprotein (apo) A1, and the relevance of the peroxisome proliferator-activated receptors (PPARs) to dyslipidaemia and insulin resistance. He adds that statins are one of the most commonly prescribed cardiovascular drugs.
|Uncontrolled Keywords:||serum, high density lipoproteins, apolipotroteins, perixisomes, insulin resistance, statins (cardiovascular agents)|
|Subjects:||R Medicine > R Medicine (General)|
R Medicine > RM Therapeutics. Pharmacology
R Medicine > RZ Other systems of medicine
|School / Department / Research Groups:||School of Science|
|Last Modified:||20 Mar 2012 16:14|
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