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Paradoxical decrease in serum high-density lipoprotein cholesterol and lipid-lowering drugs

Paradoxical decrease in serum high-density lipoprotein cholesterol and lipid-lowering drugs

Crook, M.A. (2011) Paradoxical decrease in serum high-density lipoprotein cholesterol and lipid-lowering drugs. Annals of Clinical Biochemistry, 48 (1). pp. 3-4. ISSN 0004 5632 (doi:10.1258/acb.2010.010269)

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Abstract

EDITORIAL
The author reflects on the paradoxical decline in serum high-density lipoprotein cholesterol (HDL-c) concentration using simvastatin and atorvastatin. He discusses the role of cholesterol ester transfer protein on the esterification of free cholesterol and activation by apolipoprotein (apo) A1, and the relevance of the peroxisome proliferator-activated receptors (PPARs) to dyslipidaemia and insulin resistance. He adds that statins are one of the most commonly prescribed cardiovascular drugs.

Item Type: Article
Uncontrolled Keywords: serum, high density lipoproteins, apolipotroteins, perixisomes, insulin resistance, statins (cardiovascular agents)
Subjects: R Medicine > R Medicine (General)
R Medicine > RM Therapeutics. Pharmacology
R Medicine > RZ Other systems of medicine
Pre-2014 Departments: School of Science
Related URLs:
Last Modified: 14 Oct 2016 09:19
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
URI: http://gala.gre.ac.uk/id/eprint/7581

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