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Paradoxical decrease in serum high-density lipoprotein cholesterol and lipid-lowering drugs

Crook, M.A. (2011) Paradoxical decrease in serum high-density lipoprotein cholesterol and lipid-lowering drugs. Annals of Clinical Biochemistry, 48 (1). pp. 3-4. ISSN 0004 5632

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Official URL: http://dx.doi.org/10.1258/acb.2010.010269

Abstract

EDITORIAL
The author reflects on the paradoxical decline in serum high-density lipoprotein cholesterol (HDL-c) concentration using simvastatin and atorvastatin. He discusses the role of cholesterol ester transfer protein on the esterification of free cholesterol and activation by apolipoprotein (apo) A1, and the relevance of the peroxisome proliferator-activated receptors (PPARs) to dyslipidaemia and insulin resistance. He adds that statins are one of the most commonly prescribed cardiovascular drugs.

Item Type: Article
Uncontrolled Keywords: serum, high density lipoproteins, apolipotroteins, perixisomes, insulin resistance, statins (cardiovascular agents)
Subjects: R Medicine > R Medicine (General)
R Medicine > RM Therapeutics. Pharmacology
R Medicine > RZ Other systems of medicine
School / Department / Research Groups: School of Science
Related URLs:
Last Modified: 20 Mar 2012 16:14
URI: http://gala.gre.ac.uk/id/eprint/7581

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