Synthesis and solid state study of pyridine- and pyrimidine-based fragment libraries
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Spencer, John, Patel, Hiren, Callear, Samantha K., Coles, Simon J. and Deadman, John J. (2011) Synthesis and solid state study of pyridine- and pyrimidine-based fragment libraries. Tetrahedron Letters, 52 (45). pp. 5905-5909. ISSN 0040-4039 (online)
Full text not available from this repository.Official URL: http://dx.doi.org/10.1016/j.tetlet.2011.07.147
Abstract
A library of pyridines and pyrimidines has been synthesised in excellent yields employing microwave and flow chemistry methodologies. Work-up bottlenecks have been facilitated substantially by the use of supported reagents and many of the final compounds have been studied in the solid state by single crystal X-ray diffraction.
| Item Type: | Article |
|---|---|
| Uncontrolled Keywords: | heterocycles, microwaves, parallel synthesis, piperazines, flow chemistry |
| Subjects: | Q Science > QD Chemistry |
| School / Department / Research Groups: | School of Science School of Science > Department of Pharmaceutical, Chemical & Environmental Sciences |
| Related URLs: | |
| Last Modified: | 15 Feb 2012 15:15 |
| URI: | http://gala.gre.ac.uk/id/eprint/7382 |
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