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Practical approaches of taste masking technologies in oral solid forms (Review)

Practical approaches of taste masking technologies in oral solid forms (Review)

Douroumis, Dionysios (2007) Practical approaches of taste masking technologies in oral solid forms (Review). Expert Opinion on Drug Delivery, 4 (4). pp. 417-426. ISSN 1742-5247 (Print), 1744-7593 (Online) (doi:10.1517/17425247.4.4.417)

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Abstract

In the pharmaceutical industry, taste masking techniques are applied to prevent active pharmaceutical ingredients exhibiting a bitter and unpleasant taste. The oral administration of bitter drugs through solid dosage forms requires an acceptable degree of palatability, patient tolerance and significant therapeutic value. In the recent years, enormous progress in taste masking technologies has given rise to novel strategies such as fast dissolving dosage forms, chewable tablets and coating of molten materials. Similarly, common technologies applying double coating layers, microencapsulation or even chemical modification have been employed to improve patient compliance. This review endeavours to present the practical technologies and platforms applied for taste masking and indicate the most interesting features of each approach.

Item Type: Article
Uncontrolled Keywords: taste masking, fast dissolving tablets, inclusion complexation, microencapsulation, solid dispersions
Faculty / Department / Research Group: Faculty of Engineering & Science
Faculty of Engineering & Science > Department of Pharmaceutical, Chemical & Environmental Sciences
Related URLs:
Last Modified: 17 Oct 2016 09:11
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
URI: http://gala.gre.ac.uk/id/eprint/6410

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