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Multifunctional poly(alkyl methacrylate) films for dental care

Multifunctional poly(alkyl methacrylate) films for dental care

Nielsen, Birthe V., Nevell, Thomas G., Barbu, Eugen, Smith, James R., Rees, Gareth D. and Tsibouklis, John (2011) Multifunctional poly(alkyl methacrylate) films for dental care. Biomedical Materials, 6 (1):015003. ISSN 1748-6041 (Print), 1748-605X (Online) (doi:10.1088/1748-6041/6/1/015003)

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Abstract

Towards the evaluation of non-permanent dental coatings for their capacity to impart dental-care benefits, thin films of a homologous series of comb-like poly(alkyl methacrylate)s (ethyl to octadecyl) have been deposited, from aqueous latex formulations, onto dentally relevant substrates. AFM studies have shown that the thickness (40–300 nm) and surface roughness (8–12 nm) of coherent polymer films are influenced by the degree of polymerization and by the length of the pendant chain. Of the polymers under consideration, poly(butyl methacrylate) formed a close-packed film that conferred to dental substrates a high degree of inhibition to acid-mediated erosion (about 27%), as evaluated by released-phosphate determinations. The potential utility of the coatings to act as anti-sensitivity barriers has been evaluated by determining the hydraulic conductance of coated bovine-dentine substrates; single treatments of dentine discs with poly(butyl methacrylate) or with poly(ethyl methacrylate) effected mean respective reductions in fluid flow of about 23% with respect to water-treated controls; repeated applications of the poly(butyl methacrylate) latex led to mean reductions in fluid flow of about 80%. Chromometric measurements have shown that pellicle-coated hydroxyapatite discs treated with poly(butyl methacrylate), poly(hexyl methacrylate) or poly(lauryl methacrylate) exhibit significant resistance to staining by food chromogens.

Item Type: Article
Additional Information: [1] First published 5 January 2011. [2] Issue February 2011. [3] Published as Biomedical Materials (2011), 6, (1) 015003, doi:10.1088/1748-6041/6/1/015003
Uncontrolled Keywords: poly(alkyl methacrylate)s, evaluation, non-permanent dental coatings, dental care
Subjects: Q Science > QD Chemistry
R Medicine > RK Dentistry
Faculty / Department / Research Group: Faculty of Engineering & Science > Department of Pharmaceutical, Chemical & Environmental Sciences
Related URLs:
Last Modified: 07 Dec 2016 14:14
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
URI: http://gala.gre.ac.uk/id/eprint/4354

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