Applications of DNP-NMR for the measurement of heteronuclear T1 relaxation times
Day, Iain J., Mitchell, John C., Snowden, Martin J. and Davis, Adrian L. (2007) Applications of DNP-NMR for the measurement of heteronuclear T1 relaxation times. Journal of Magnetic Resonance, 187 (2). pp. 216-224. ISSN 1090-7807 (doi:10.1016/j.jmr.2007.04.015)Full text not available from this repository.
Measurement of heteronuclear spin-lattice relaxation times is hampered by both low natural abundance and low detection sensitivity. Combined with typically long relaxation times, this results in extended acquisition times which often renders the experiment impractical. Recently a variant of dynamic nuclear polarisation has been demonstrated in which enhanced nuclear spin polarisation, generated in the cryo-solid state, is transferred to the liquid state for detection. Combining this approach with small flip angle pulse trains, similar to the FLASH-T(1) imaging sequence, allows the rapid determination of spin-lattice relaxation times. In this paper we explore this method and its application to the measurement of T(1) for both carbon-13 and nitrogen-15 at natural abundance. The effects of RF inhomogeneity and the influence of proton decoupling in the context of this experiment are also investigated.
|Uncontrolled Keywords:||dynamic nuclear polarisation, spin-lattice relaxation, heteronuclear|
|Subjects:||Q Science > QC Physics|
|School / Department / Research Groups:||School of Science|
School of Science > Department of Medway Sciences
School of Science > Department of Pharmaceutical, Chemical & Environmental Sciences
|Last Modified:||20 Jul 2012 10:09|
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