The implementation of FT-Raman spectroscopy to study solid state moisture induced changes in the crystallographic nature of pharmaceutical excipients - a lesson in humidity
Tools
Tools
Tools
Major, P.J., Cornelius, V.J., Mitchell, J.C. and Murphy, J. (2007) The implementation of FT-Raman spectroscopy to study solid state moisture induced changes in the crystallographic nature of pharmaceutical excipients - a lesson in humidity. Journal of Pharmacy and Pharmacology, 59 (S1). A38-A38. ISSN 0022-3573
Full text not available from this repository.Official URL: http://dx.doi.org/10.1211/002235707781849999
Abstract
An aqueous solution of sucrose was lyophilised, producing amorphous sucrose. This wasthen stored under different humidity at 25ºC for 1 week, allowing some samples tocrystallise. FT-Raman spectroscopy and PXRD have been successfully shown toqualitatively distinguish between amorphous and crystalline samples of sucrose. The datafrom the two techniques is complementary.
| Item Type: | Article |
|---|---|
| Additional Information: | [1] Presented at BPC 2007, 10-12 Sep 2007, Manchester, UK. Meeting Abstract 99. [2] This article (no. 99) was published in Supplement 1, of the Journal of Pharmacy and Pharmacology 2007, 59, Special Issue: BPC Science Abstracts. |
| Uncontrolled Keywords: | FT-Raman, PXRD, sucrose, humidity, amorphous, crystalline |
| Subjects: | Q Science > QD Chemistry R Medicine > RS Pharmacy and materia medica |
| School / Department / Research Groups: | School of Science School of Science > Department of Medway Sciences |
| Related URLs: | |
| Last Modified: | 27 Nov 2012 09:53 |
| URI: | http://gala.gre.ac.uk/id/eprint/2521 |
Actions (login required)
| View Item |