A preliminary investigation of the in vitro bioactivity of white Portland cement
Coleman, Nichola J., Nicholson, John W. and Awosanya, Kunle (2007) A preliminary investigation of the in vitro bioactivity of white Portland cement. Cement and Concrete Research, 37 (11). pp. 1518-1523. ISSN 0008-8846Full text not available from this repository.
Freshly-mixed and partially-cured ordinary Portland cement (OPC) pastes have been shown to exhibit good biological compatibility with a range of cells and tissue-types; particularly those associated with bone formation. Formulations based on OPC have been used as dental restoratives and are now being investigated for their potential use in orthopaedic repair. Despite the current clinical interest in OPCs, very little is known about their chemistry in the physiological environment. In this respect, research to investigate aspects of the interactions between a white Portland cement (WPC) paste and simulated body fluid (SBF) has been carried out in vitro. Exposure to SBF has been found to promote the precipitation of a layer of 'bone-like' hydroxyapatite on the surface of WPC paste which underpins its ability to integrate with living tissue. The dissolution of portlandite and formation of calcite were also observed on contact with SBF.
|Uncontrolled Keywords:||cement paste: Portland cement; bioactivity|
|Subjects:||Q Science > QD Chemistry|
R Medicine > RS Pharmacy and materia medica
|School / Department / Research Groups:||School of Science|
School of Science > Department of Pharmaceutical, Chemical & Environmental Sciences
|Last Modified:||01 Apr 2011 14:13|
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