Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template
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Spencer, John, Gaffen, John, Grifin, Eric, Harper, Elaine A., Linney, Ian D., McDonald, Iain M., Roberts, Sonia P., Shaxted, Mark E., Adatia, Trushar and Bashall, Alan (2008) Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template. Bioorganic & Medicinal Chemistry, 16 (6). pp. 2974-2983. ISSN 0968-0896
Full text not available from this repository.Official URL: http://www.sciencedirect.com/science/article/B6TF8...
Abstract
Novel, achiral 1H-1,3,5-benzotriazepine-2,4(3H,5H)-diones have been prepared and structurally characterized. These compounds are potent CCK2 receptor antagonists that display a high degree of selectivity over CCK1 receptors.
| Item Type: | Article |
|---|---|
| Additional Information: | Erratum to "Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template" [Bioorg. Med. Chem. 16 (2008) 2974–2983] Bioorganic & Medicinal Chemistry, Volume 16, Issue 16, 15 August 2008, Page 7862. Adds John Spencer as corresponding author. No other errata. |
| Uncontrolled Keywords: | CCK, CCK2, gastrin, antagonist, benzotriazepine |
| Subjects: | R Medicine > RM Therapeutics. Pharmacology |
| School / Department / Research Groups: | School of Science School of Science > Department of Pharmaceutical, Chemical & Environmental Sciences |
| Related URLs: | |
| Last Modified: | 01 Apr 2011 16:13 |
| URI: | http://gala.gre.ac.uk/id/eprint/2222 |
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