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Advanced therapeutic dressings for effective wound healing

Advanced therapeutic dressings for effective wound healing

Boateng, Joshua ORCID: 0000-0002-6310-729X and Catanzano, Ovidio (2015) Advanced therapeutic dressings for effective wound healing. Journal of Pharmaceutical Sciences, 104 (11). pp. 3653-3680. ISSN 0022-3549 (Print), 1520-6017 (Online) (doi:DOI 10.1002/jps.24610)

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Abstract

Advanced therapeutic dressings that take active part in wound healing to achieve rapid and complete healing of chronic wounds is of current research interest. There is a desire for novel strategies to achieve expeditious wound healing due to the enormous financial burden worldwide. This paper reviews the current state of wound healing and wound management products, with emphasis on the demand for more advanced forms of wound therapy and some of the current challenges and driving forces behind this demand. The paper reviews information mainly from peer reviewed literature and other publicly available sources such as the FDA. A major focus is the treatment of chronic wounds including amputations, diabetic and leg ulcers, pressure sores, surgical and traumatic wounds (e.g. accidents and burns) where patient immunity is low and the risk of infections and complications are high. The main dressings include medicated moist dressings, tissue engineered substitutes, biomaterials based biological dressings, biological and naturally derived dressings, medicated sutures and various combinations of the above classes. Finally, the review briefly discusses possible prospects of advanced wound healing including some of the emerging approaches such as hyperbaric oxygen, negative pressure wound therapy and laser wound healing, in routine clinical care.

Item Type: Article
Additional Information: This is the peer reviewed version of above fully cited article and may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.
Uncontrolled Keywords: natural products; wound healing; polymeric biomaterials; macromolecular drug delivery; tissue engineering;
Faculty / Department / Research Group: Faculty of Engineering & Science > Department of Pharmaceutical, Chemical & Environmental Sciences
Last Modified: 17 Oct 2016 09:13
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
URI: http://gala.gre.ac.uk/id/eprint/13804

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