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Alginate dressing
Boateng, Joshua ORCID: 0000-0002-6310-729X , Momoh, Frederick, Richardson, Simon ORCID: 0000-0002-7927-0649 , Chowdhry, Babur and Mitchell, John ORCID: 0000-0003-2945-3292 (2015) Development functional characterization of alginate dressing as potential protein delivery system for wound healing. International Journal of Biological Macromolecules, 81. pp. 137-150. ISSN 0141-8130 (Print), 1879-0003 (Online) (doi:https://doi.org/10.1016/j.ijbiomac.2015.07.037)
Antimicrobial dressing
Pawar, Harshavardhan V., Tetteh, John, Debrah, Philip and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2018) Comparison of in vitro antibacterial activity of streptomycin-diclofenac loaded composite biomaterial dressings with commercial silver based antimicrobial wound dressings. International Journal of Biological Macromolecules, 121. pp. 191-199. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2018.10.023)
Bacterial infection
Pawar, Harshavardhan V., Tetteh, John, Debrah, Philip and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2018) Comparison of in vitro antibacterial activity of streptomycin-diclofenac loaded composite biomaterial dressings with commercial silver based antimicrobial wound dressings. International Journal of Biological Macromolecules, 121. pp. 191-199. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2018.10.023)
bio-polymeric
Boateng, Joshua ORCID: 0000-0002-6310-729X , Burgos-Amador, Rocio, Okeke, Obinna and Pawar, Harshavardhan (2015) Composite alginate and gelatin based bio-polymeric wafers containing silver sulfadiazine for wound healing. International Journal of Biological Macromolecules, 79. pp. 63-71. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2015.04.048)
bioactive
Hurt, A. P., Getti, G. ORCID: 0000-0003-1402-8496 and Coleman, N.J. (2014) Bioactivity and biocompatibility of a chitosan-tobermorite composite membrane for guided tissue regeneration. International Journal of Biological Macromolecules, 64. pp. 11-16. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2013.11.020)
BRL-3a cells
Liu, Xiaoze, Zhang, Wen, Chen, Jingwen, Fu, Ruihui, Lin, Xue, Zhou, Shaobo ORCID: 0000-0001-5214-2973 and Wang, LU (2024) Investigating the inhibition of xanthine oxidase by five catechins: kinetic studies, spectroscopy, molecular docking, and dynamics simulations. International Journal of Biological Macromolecules, 281 (Part 1):136231. ISSN 0141-8130 (Print), 1879-0003 (Online) (doi:https://doi.org/10.1016/j.ijbiomac.2024.136231)
buccal delivery
Ayensu, Isaac, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2012) Effect of membrane dialysis on characteristics of lyophilised chitosan wafers for potential buccal delivery of proteins. International Journal of Biological Macromolecules, 50 (4). pp. 905-909. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2012.02.014)
Boateng, Joshua S. ORCID: 0000-0002-6310-729X and Okeke, Obinna C. (2016) Composite HPMC and sodium alginate based buccal formulations for nicotine replacement therapy. International Journal of Biological Macromolecules, 91. pp. 31-44. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2016.05.079)
Carrageenan
Pawar, Harshavardhan V., Tetteh, John, Debrah, Philip and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2018) Comparison of in vitro antibacterial activity of streptomycin-diclofenac loaded composite biomaterial dressings with commercial silver based antimicrobial wound dressings. International Journal of Biological Macromolecules, 121. pp. 191-199. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2018.10.023)
catechins
Liu, Xiaoze, Zhang, Wen, Chen, Jingwen, Fu, Ruihui, Lin, Xue, Zhou, Shaobo ORCID: 0000-0001-5214-2973 and Wang, LU (2024) Investigating the inhibition of xanthine oxidase by five catechins: kinetic studies, spectroscopy, molecular docking, and dynamics simulations. International Journal of Biological Macromolecules, 281 (Part 1):136231. ISSN 0141-8130 (Print), 1879-0003 (Online) (doi:https://doi.org/10.1016/j.ijbiomac.2024.136231)
chitosan
Ayensu, Isaac, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2012) Effect of membrane dialysis on characteristics of lyophilised chitosan wafers for potential buccal delivery of proteins. International Journal of Biological Macromolecules, 50 (4). pp. 905-909. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2012.02.014)
Dong, Shuai, HU, Shu-Min, Yu, Shaobo, Zhou, Shaobo ORCID: 0000-0001-5214-2973 and Zhou, Tao (2023) Soybean protein isolate/chitosan complex-rutin microcapsules. International Journal of Biological Macromolecules, 243:125323. pp. 1-9. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2023.125323)
Hurt, A. P., Getti, G. ORCID: 0000-0003-1402-8496 and Coleman, N.J. (2014) Bioactivity and biocompatibility of a chitosan-tobermorite composite membrane for guided tissue regeneration. International Journal of Biological Macromolecules, 64. pp. 11-16. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2013.11.020)
Chronic wound
Pawar, Harshavardhan V., Tetteh, John, Debrah, Philip and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2018) Comparison of in vitro antibacterial activity of streptomycin-diclofenac loaded composite biomaterial dressings with commercial silver based antimicrobial wound dressings. International Journal of Biological Macromolecules, 121. pp. 191-199. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2018.10.023)
citrus essential oil
Yu, Si-Jia, Hu, Shu-Min, Zhu, Yu-Zhu, Zhou, Shaobo ORCID: 0000-0001-5214-2973 , Dong, Shuai and Zhou, Tao (2023) Pickering emulsions stabilized by soybean protein isolate/chitosan hydrochloride complex and their applications in essential oil delivery. International Journal of Biological Macromolecules, 250:126146. pp. 1-12. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2023.126146)
Diclofenac
Pawar, Harshavardhan V., Tetteh, John, Debrah, Philip and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2018) Comparison of in vitro antibacterial activity of streptomycin-diclofenac loaded composite biomaterial dressings with commercial silver based antimicrobial wound dressings. International Journal of Biological Macromolecules, 121. pp. 191-199. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2018.10.023)
EpiCornealâ„¢
Tighsazzadeh, Mohammad and Boateng, Joshua ORCID: 0000-0002-6310-729X (2024) Matrix hyaluronic acid and bilayer poly-hydroxyethyl methacrylate-hyaluronic acid films as potential ocular drug delivery platforms. International Journal of Biological Macromolecules, 260 (Part 2):129496. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2024.129496)
Films
Boateng, Joshua S. ORCID: 0000-0002-6310-729X and Okeke, Obinna C. (2016) Composite HPMC and sodium alginate based buccal formulations for nicotine replacement therapy. International Journal of Biological Macromolecules, 91. pp. 31-44. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2016.05.079)
fusiforme
Wan, Cheng, Jiang, Hui, Tang, Meng-Ting, Zhou, Tao and Zhou, Shaobo ORCID: 0000-0001-5214-2973 (2022) Purification, physico-chemical properties and antioxidant activity of polysaccharides from Sargassum fusiforme by hydrogen peroxide/ascorbic acid-assisted extraction. International Journal of Biological Macromolecules, 223 (Part A). pp. 490-499. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2022.11.030)
gastrointestinal conditions
Chen, Liang, Qian, Wen-Wen, Zhou, Shaobo ORCID: 0000-0001-5214-2973 , Zhou, Tao and Gu, Qing (2023) Fabrication of whey protein/pectin double layer microcapsules for improving survival of Lacticaseibacillus rhamnosus ZFM231. International Journal of Biological Macromolecules, 242 (4):125030. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2023.125030)
glaucoma
Tighsazzadeh, Mohammad and Boateng, Joshua ORCID: 0000-0002-6310-729X (2024) Matrix hyaluronic acid and bilayer poly-hydroxyethyl methacrylate-hyaluronic acid films as potential ocular drug delivery platforms. International Journal of Biological Macromolecules, 260 (Part 2):129496. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2024.129496)
GST-GFP Proteins
Boateng, Joshua ORCID: 0000-0002-6310-729X , Momoh, Frederick, Richardson, Simon ORCID: 0000-0002-7927-0649 , Chowdhry, Babur and Mitchell, John ORCID: 0000-0003-2945-3292 (2015) Development functional characterization of alginate dressing as potential protein delivery system for wound healing. International Journal of Biological Macromolecules, 81. pp. 137-150. ISSN 0141-8130 (Print), 1879-0003 (Online) (doi:https://doi.org/10.1016/j.ijbiomac.2015.07.037)
HPMC
Boateng, Joshua S. ORCID: 0000-0002-6310-729X and Okeke, Obinna C. (2016) Composite HPMC and sodium alginate based buccal formulations for nicotine replacement therapy. International Journal of Biological Macromolecules, 91. pp. 31-44. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2016.05.079)
hyaluronic acid
Tighsazzadeh, Mohammad and Boateng, Joshua ORCID: 0000-0002-6310-729X (2024) Matrix hyaluronic acid and bilayer poly-hydroxyethyl methacrylate-hyaluronic acid films as potential ocular drug delivery platforms. International Journal of Biological Macromolecules, 260 (Part 2):129496. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2024.129496)
Lacticaseibacillus rhamnosus
Chen, Liang, Qian, Wen-Wen, Zhou, Shaobo ORCID: 0000-0001-5214-2973 , Zhou, Tao and Gu, Qing (2023) Fabrication of whey protein/pectin double layer microcapsules for improving survival of Lacticaseibacillus rhamnosus ZFM231. International Journal of Biological Macromolecules, 242 (4):125030. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2023.125030)
lyophilised wafers
Ayensu, Isaac, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2012) Effect of membrane dialysis on characteristics of lyophilised chitosan wafers for potential buccal delivery of proteins. International Journal of Biological Macromolecules, 50 (4). pp. 905-909. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2012.02.014)
membrane dialysis
Ayensu, Isaac, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2012) Effect of membrane dialysis on characteristics of lyophilised chitosan wafers for potential buccal delivery of proteins. International Journal of Biological Macromolecules, 50 (4). pp. 905-909. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2012.02.014)
microcapsule
Chen, Liang, Qian, Wen-Wen, Zhou, Shaobo ORCID: 0000-0001-5214-2973 , Zhou, Tao and Gu, Qing (2023) Fabrication of whey protein/pectin double layer microcapsules for improving survival of Lacticaseibacillus rhamnosus ZFM231. International Journal of Biological Macromolecules, 242 (4):125030. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2023.125030)
molecular docking
Liu, Xiaoze, Zhang, Wen, Chen, Jingwen, Fu, Ruihui, Lin, Xue, Zhou, Shaobo ORCID: 0000-0001-5214-2973 and Wang, LU (2024) Investigating the inhibition of xanthine oxidase by five catechins: kinetic studies, spectroscopy, molecular docking, and dynamics simulations. International Journal of Biological Macromolecules, 281 (Part 1):136231. ISSN 0141-8130 (Print), 1879-0003 (Online) (doi:https://doi.org/10.1016/j.ijbiomac.2024.136231)
molecular dynamics simulation
Liu, Xiaoze, Zhang, Wen, Chen, Jingwen, Fu, Ruihui, Lin, Xue, Zhou, Shaobo ORCID: 0000-0001-5214-2973 and Wang, LU (2024) Investigating the inhibition of xanthine oxidase by five catechins: kinetic studies, spectroscopy, molecular docking, and dynamics simulations. International Journal of Biological Macromolecules, 281 (Part 1):136231. ISSN 0141-8130 (Print), 1879-0003 (Online) (doi:https://doi.org/10.1016/j.ijbiomac.2024.136231)
mucoadhesion
Ayensu, Isaac, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2012) Effect of membrane dialysis on characteristics of lyophilised chitosan wafers for potential buccal delivery of proteins. International Journal of Biological Macromolecules, 50 (4). pp. 905-909. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2012.02.014)
Nicotine
Boateng, Joshua S. ORCID: 0000-0002-6310-729X and Okeke, Obinna C. (2016) Composite HPMC and sodium alginate based buccal formulations for nicotine replacement therapy. International Journal of Biological Macromolecules, 91. pp. 31-44. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2016.05.079)
pickering emulsions
Yu, Si-Jia, Hu, Shu-Min, Zhu, Yu-Zhu, Zhou, Shaobo ORCID: 0000-0001-5214-2973 , Dong, Shuai and Zhou, Tao (2023) Pickering emulsions stabilized by soybean protein isolate/chitosan hydrochloride complex and their applications in essential oil delivery. International Journal of Biological Macromolecules, 250:126146. pp. 1-12. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2023.126146)
poly-hydroxyethyl methacrylate
Tighsazzadeh, Mohammad and Boateng, Joshua ORCID: 0000-0002-6310-729X (2024) Matrix hyaluronic acid and bilayer poly-hydroxyethyl methacrylate-hyaluronic acid films as potential ocular drug delivery platforms. International Journal of Biological Macromolecules, 260 (Part 2):129496. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2024.129496)
polysaccharides
Wan, Cheng, Jiang, Hui, Tang, Meng-Ting, Zhou, Tao and Zhou, Shaobo ORCID: 0000-0001-5214-2973 (2022) Purification, physico-chemical properties and antioxidant activity of polysaccharides from Sargassum fusiforme by hydrogen peroxide/ascorbic acid-assisted extraction. International Journal of Biological Macromolecules, 223 (Part A). pp. 490-499. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2022.11.030)
porcine cornea
Tighsazzadeh, Mohammad and Boateng, Joshua ORCID: 0000-0002-6310-729X (2024) Matrix hyaluronic acid and bilayer poly-hydroxyethyl methacrylate-hyaluronic acid films as potential ocular drug delivery platforms. International Journal of Biological Macromolecules, 260 (Part 2):129496. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2024.129496)
protein delivery
Ayensu, Isaac, Mitchell, John C. ORCID: 0000-0003-2945-3292 and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2012) Effect of membrane dialysis on characteristics of lyophilised chitosan wafers for potential buccal delivery of proteins. International Journal of Biological Macromolecules, 50 (4). pp. 905-909. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2012.02.014)
purification
Wan, Cheng, Jiang, Hui, Tang, Meng-Ting, Zhou, Tao and Zhou, Shaobo ORCID: 0000-0001-5214-2973 (2022) Purification, physico-chemical properties and antioxidant activity of polysaccharides from Sargassum fusiforme by hydrogen peroxide/ascorbic acid-assisted extraction. International Journal of Biological Macromolecules, 223 (Part A). pp. 490-499. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2022.11.030)
rutin
Dong, Shuai, HU, Shu-Min, Yu, Shaobo, Zhou, Shaobo ORCID: 0000-0001-5214-2973 and Zhou, Tao (2023) Soybean protein isolate/chitosan complex-rutin microcapsules. International Journal of Biological Macromolecules, 243:125323. pp. 1-9. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2023.125323)
Sargassum
Wan, Cheng, Jiang, Hui, Tang, Meng-Ting, Zhou, Tao and Zhou, Shaobo ORCID: 0000-0001-5214-2973 (2022) Purification, physico-chemical properties and antioxidant activity of polysaccharides from Sargassum fusiforme by hydrogen peroxide/ascorbic acid-assisted extraction. International Journal of Biological Macromolecules, 223 (Part A). pp. 490-499. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2022.11.030)
Silver dressing
Pawar, Harshavardhan V., Tetteh, John, Debrah, Philip and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2018) Comparison of in vitro antibacterial activity of streptomycin-diclofenac loaded composite biomaterial dressings with commercial silver based antimicrobial wound dressings. International Journal of Biological Macromolecules, 121. pp. 191-199. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2018.10.023)
Sodium alginate
Boateng, Joshua S. ORCID: 0000-0002-6310-729X and Okeke, Obinna C. (2016) Composite HPMC and sodium alginate based buccal formulations for nicotine replacement therapy. International Journal of Biological Macromolecules, 91. pp. 31-44. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2016.05.079)
Pawar, Harshavardhan V., Tetteh, John, Debrah, Philip and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2018) Comparison of in vitro antibacterial activity of streptomycin-diclofenac loaded composite biomaterial dressings with commercial silver based antimicrobial wound dressings. International Journal of Biological Macromolecules, 121. pp. 191-199. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2018.10.023)
soybean protein isolate
Dong, Shuai, HU, Shu-Min, Yu, Shaobo, Zhou, Shaobo ORCID: 0000-0001-5214-2973 and Zhou, Tao (2023) Soybean protein isolate/chitosan complex-rutin microcapsules. International Journal of Biological Macromolecules, 243:125323. pp. 1-9. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2023.125323)
soybean protein isolate-chitosan hydrochloride
Yu, Si-Jia, Hu, Shu-Min, Zhu, Yu-Zhu, Zhou, Shaobo ORCID: 0000-0001-5214-2973 , Dong, Shuai and Zhou, Tao (2023) Pickering emulsions stabilized by soybean protein isolate/chitosan hydrochloride complex and their applications in essential oil delivery. International Journal of Biological Macromolecules, 250:126146. pp. 1-12. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2023.126146)
Streptomycin
Pawar, Harshavardhan V., Tetteh, John, Debrah, Philip and Boateng, Joshua S. ORCID: 0000-0002-6310-729X (2018) Comparison of in vitro antibacterial activity of streptomycin-diclofenac loaded composite biomaterial dressings with commercial silver based antimicrobial wound dressings. International Journal of Biological Macromolecules, 121. pp. 191-199. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2018.10.023)
Timolol
Tighsazzadeh, Mohammad and Boateng, Joshua ORCID: 0000-0002-6310-729X (2024) Matrix hyaluronic acid and bilayer poly-hydroxyethyl methacrylate-hyaluronic acid films as potential ocular drug delivery platforms. International Journal of Biological Macromolecules, 260 (Part 2):129496. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2024.129496)
tobermorite
Hurt, A. P., Getti, G. ORCID: 0000-0003-1402-8496 and Coleman, N.J. (2014) Bioactivity and biocompatibility of a chitosan-tobermorite composite membrane for guided tissue regeneration. International Journal of Biological Macromolecules, 64. pp. 11-16. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2013.11.020)
wafers
Boateng, Joshua ORCID: 0000-0002-6310-729X , Burgos-Amador, Rocio, Okeke, Obinna and Pawar, Harshavardhan (2015) Composite alginate and gelatin based bio-polymeric wafers containing silver sulfadiazine for wound healing. International Journal of Biological Macromolecules, 79. pp. 63-71. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2015.04.048)
Boateng, Joshua S. ORCID: 0000-0002-6310-729X and Okeke, Obinna C. (2016) Composite HPMC and sodium alginate based buccal formulations for nicotine replacement therapy. International Journal of Biological Macromolecules, 91. pp. 31-44. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2016.05.079)
wound healing
Boateng, Joshua ORCID: 0000-0002-6310-729X , Burgos-Amador, Rocio, Okeke, Obinna and Pawar, Harshavardhan (2015) Composite alginate and gelatin based bio-polymeric wafers containing silver sulfadiazine for wound healing. International Journal of Biological Macromolecules, 79. pp. 63-71. ISSN 0141-8130 (doi:https://doi.org/10.1016/j.ijbiomac.2015.04.048)
Boateng, Joshua ORCID: 0000-0002-6310-729X , Momoh, Frederick, Richardson, Simon ORCID: 0000-0002-7927-0649 , Chowdhry, Babur and Mitchell, John ORCID: 0000-0003-2945-3292 (2015) Development functional characterization of alginate dressing as potential protein delivery system for wound healing. International Journal of Biological Macromolecules, 81. pp. 137-150. ISSN 0141-8130 (Print), 1879-0003 (Online) (doi:https://doi.org/10.1016/j.ijbiomac.2015.07.037)
xanthine oxidase
Liu, Xiaoze, Zhang, Wen, Chen, Jingwen, Fu, Ruihui, Lin, Xue, Zhou, Shaobo ORCID: 0000-0001-5214-2973 and Wang, LU (2024) Investigating the inhibition of xanthine oxidase by five catechins: kinetic studies, spectroscopy, molecular docking, and dynamics simulations. International Journal of Biological Macromolecules, 281 (Part 1):136231. ISSN 0141-8130 (Print), 1879-0003 (Online) (doi:https://doi.org/10.1016/j.ijbiomac.2024.136231)