Antiarrhythmics

Roselli, Mariagrazia, Carocci, Alessia, Budriesi, Roberta, Micucci, Matteo, Toma, Maddalena, Di Cesare Mannelli, Lorenzo, Lovece, Angelo, Catalano, Alessia, Cavalluzzi, Maria Maddalena, Bruno, Claudio, De Palma, Annalisa, Contino, Marialessandra, Perrone, Maria Grazia, Colabufo, Nicola Antonio, Chiarini, Alberto, Franchini, Carlo, Ghelardini, Carla, Habtemariam, Solomon and Lentini, Giovanni (2016) Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues. European Journal of Medicinal Chemistry, 121. pp. 300-307. ISSN 0223-5234 (doi:https://doi.org/10.1016/j.ejmech.2016.05.046)

decision trees

Newby, Danielle, Freitas, Alex. A. and Ghafourian, Taravat (2015) Decision trees to characterise the roles of permeability and solubility on the prediction of oral absorption. European Journal of Medicinal Chemistry, 90. pp. 751-765. ISSN 0223-5234 (doi:https://doi.org/10.1016/j.ejmech.2014.12.006)

Inotropism

Roselli, Mariagrazia, Carocci, Alessia, Budriesi, Roberta, Micucci, Matteo, Toma, Maddalena, Di Cesare Mannelli, Lorenzo, Lovece, Angelo, Catalano, Alessia, Cavalluzzi, Maria Maddalena, Bruno, Claudio, De Palma, Annalisa, Contino, Marialessandra, Perrone, Maria Grazia, Colabufo, Nicola Antonio, Chiarini, Alberto, Franchini, Carlo, Ghelardini, Carla, Habtemariam, Solomon and Lentini, Giovanni (2016) Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues. European Journal of Medicinal Chemistry, 121. pp. 300-307. ISSN 0223-5234 (doi:https://doi.org/10.1016/j.ejmech.2016.05.046)

intestinal absorption

Newby, Danielle, Freitas, Alex. A. and Ghafourian, Taravat (2015) Decision trees to characterise the roles of permeability and solubility on the prediction of oral absorption. European Journal of Medicinal Chemistry, 90. pp. 751-765. ISSN 0223-5234 (doi:https://doi.org/10.1016/j.ejmech.2014.12.006)

Mexiletine

Roselli, Mariagrazia, Carocci, Alessia, Budriesi, Roberta, Micucci, Matteo, Toma, Maddalena, Di Cesare Mannelli, Lorenzo, Lovece, Angelo, Catalano, Alessia, Cavalluzzi, Maria Maddalena, Bruno, Claudio, De Palma, Annalisa, Contino, Marialessandra, Perrone, Maria Grazia, Colabufo, Nicola Antonio, Chiarini, Alberto, Franchini, Carlo, Ghelardini, Carla, Habtemariam, Solomon and Lentini, Giovanni (2016) Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues. European Journal of Medicinal Chemistry, 121. pp. 300-307. ISSN 0223-5234 (doi:https://doi.org/10.1016/j.ejmech.2016.05.046)

MW-assisted synthesis

Roselli, Mariagrazia, Carocci, Alessia, Budriesi, Roberta, Micucci, Matteo, Toma, Maddalena, Di Cesare Mannelli, Lorenzo, Lovece, Angelo, Catalano, Alessia, Cavalluzzi, Maria Maddalena, Bruno, Claudio, De Palma, Annalisa, Contino, Marialessandra, Perrone, Maria Grazia, Colabufo, Nicola Antonio, Chiarini, Alberto, Franchini, Carlo, Ghelardini, Carla, Habtemariam, Solomon and Lentini, Giovanni (2016) Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues. European Journal of Medicinal Chemistry, 121. pp. 300-307. ISSN 0223-5234 (doi:https://doi.org/10.1016/j.ejmech.2016.05.046)

P-glycoprotein

Roselli, Mariagrazia, Carocci, Alessia, Budriesi, Roberta, Micucci, Matteo, Toma, Maddalena, Di Cesare Mannelli, Lorenzo, Lovece, Angelo, Catalano, Alessia, Cavalluzzi, Maria Maddalena, Bruno, Claudio, De Palma, Annalisa, Contino, Marialessandra, Perrone, Maria Grazia, Colabufo, Nicola Antonio, Chiarini, Alberto, Franchini, Carlo, Ghelardini, Carla, Habtemariam, Solomon and Lentini, Giovanni (2016) Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues. European Journal of Medicinal Chemistry, 121. pp. 300-307. ISSN 0223-5234 (doi:https://doi.org/10.1016/j.ejmech.2016.05.046)

permeability

Newby, Danielle, Freitas, Alex. A. and Ghafourian, Taravat (2015) Decision trees to characterise the roles of permeability and solubility on the prediction of oral absorption. European Journal of Medicinal Chemistry, 90. pp. 751-765. ISSN 0223-5234 (doi:https://doi.org/10.1016/j.ejmech.2014.12.006)

QSAR

Newby, Danielle, Freitas, Alex. A. and Ghafourian, Taravat (2015) Decision trees to characterise the roles of permeability and solubility on the prediction of oral absorption. European Journal of Medicinal Chemistry, 90. pp. 751-765. ISSN 0223-5234 (doi:https://doi.org/10.1016/j.ejmech.2014.12.006)

solubility

Newby, Danielle, Freitas, Alex. A. and Ghafourian, Taravat (2015) Decision trees to characterise the roles of permeability and solubility on the prediction of oral absorption. European Journal of Medicinal Chemistry, 90. pp. 751-765. ISSN 0223-5234 (doi:https://doi.org/10.1016/j.ejmech.2014.12.006)