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Items where Author is "Varshavi, Dorsa"

Items where Author is "Varshavi, Dorsa"

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2 3-butanediol 6-hydroxy-6-methyl-heptan-3-one ageing anti-obesogenic antibiotic bioRxiv preprint server biosynthesis body weight C57BL/6J cells cholesterol cholesterol-lowering colorectal cancer Drug Metabolism and Disposition FMO5 FMO5 KO genetic knock-out glucose gut microbiome HCT116 humans hypotaurine KRAS malic enzyme 1 medicine metabolic profiling metabolite Metabolite identification metabolomics metabonomics Metabonomics etabolomics Molecular structure mouse mutations NMR NMR (nuclear magnetic resonance) spectroscopy Nuclear magnetic resonance (NMR) spectroscopy Pharmacometabolomics Pharmacometabonomics plasma Prediction of PK stomach SW48 taurine urine white adipose tissue
Number of items: 66.

2

Everett, Jeremy, Varshavi, Dorsa, Shephard, Elizabeth, and Veeravalli, Sunil (2021) Patent - Treatment of obesity and related conditions. .

3-butanediol

Everett, Jeremy, Varshavi, Dorsa, Shephard, Elizabeth, and Veeravalli, Sunil (2021) Patent - Treatment of obesity and related conditions. .

6-hydroxy-6-methyl-heptan-3-one

Scott, Flora H., Varshavi, Dorsa, Veeravalli, Sunil, Phillips, Ian R., Veselkov, Kirill, Strittmatter, Nicole, Takats, Zoltan, Shephard, Elizabeth A. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2018) Metabolic biomarkers of ageing in C57BL/6J wild-type and flavin-containing monooxygenase 5 (FMO5)-knockout mice. Frontiers in Molecular Biosciences, 5:28. ISSN 2296-889X (Online) (doi:https://doi.org/10.3389/fmolb.2018.00028)

ageing

Scott, Flora H., Varshavi, Dorsa, Veeravalli, Sunil, Phillips, Ian R., Veselkov, Kirill, Strittmatter, Nicole, Takats, Zoltan, Shephard, Elizabeth A. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2018) Metabolic biomarkers of ageing in C57BL/6J wild-type and flavin-containing monooxygenase 5 (FMO5)-knockout mice. Frontiers in Molecular Biosciences, 5:28. ISSN 2296-889X (Online) (doi:https://doi.org/10.3389/fmolb.2018.00028)

anti-obesogenic

Everett, Jeremy, Varshavi, Dorsa, Shephard, Elizabeth, and Veeravalli, Sunil (2021) Patent - Treatment of obesity and related conditions. .

antibiotic

Veeravalli, Sunil, Varshavi, Dorsa, Scott, Flora H, Varshavi, Dorna, Pullen, Francis, Veselkov, Kirill, Phillips, Ian R, Everett, Jeremy ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth (2022) Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5-/- mice, decreases plasma cholesterol and epididymal fat deposition. Frontiers in Physiology, 13:859681. pp. 1-13. ISSN 1664-042X (Online) (doi:https://doi.org/10.3389/fphys.2022.859681)

bioRxiv preprint server

Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth A. (2020) Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine. Drug Metabolism and Disposition, 48 (4). ISSN 0090-9556 (Print), 1521-009X (Online) (doi:https://doi.org/10.1124/dmd.119.089995)

biosynthesis

Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth A. (2020) Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine. Drug Metabolism and Disposition, 48 (4). ISSN 0090-9556 (Print), 1521-009X (Online) (doi:https://doi.org/10.1124/dmd.119.089995)

body weight

Gonzalez Malagon, Sandra G., Melidoni, Anna N., Hernandez, Diana, Omar, Bilal A., Houseman, Lyndsey, Veeravalli, Sunil, Scott, Flora, Varshavi, Dorsa, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Tsuchiya, Yugo, Timms, John F., Phillips, Ian R. and Shephard, Elizabeth A. (2015) The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing. Biochemical Pharmacology, 96 (3). pp. 267-277. ISSN 0006-2952 (doi:https://doi.org/10.1016/j.bcp.2015.05.013)

C57BL/6J

Scott, Flora H., Varshavi, Dorsa, Veeravalli, Sunil, Phillips, Ian R., Veselkov, Kirill, Strittmatter, Nicole, Takats, Zoltan, Shephard, Elizabeth A. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2018) Metabolic biomarkers of ageing in C57BL/6J wild-type and flavin-containing monooxygenase 5 (FMO5)-knockout mice. Frontiers in Molecular Biosciences, 5:28. ISSN 2296-889X (Online) (doi:https://doi.org/10.3389/fmolb.2018.00028)

cells

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-021-01852-w)

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-020-01674-2)

cholesterol

Gonzalez Malagon, Sandra G., Melidoni, Anna N., Hernandez, Diana, Omar, Bilal A., Houseman, Lyndsey, Veeravalli, Sunil, Scott, Flora, Varshavi, Dorsa, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Tsuchiya, Yugo, Timms, John F., Phillips, Ian R. and Shephard, Elizabeth A. (2015) The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing. Biochemical Pharmacology, 96 (3). pp. 267-277. ISSN 0006-2952 (doi:https://doi.org/10.1016/j.bcp.2015.05.013)

cholesterol-lowering

Everett, Jeremy, Varshavi, Dorsa, Shephard, Elizabeth, and Veeravalli, Sunil (2021) Patent - Treatment of obesity and related conditions. .

colorectal cancer

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-021-01852-w)

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-020-01674-2)

Drug Metabolism and Disposition

Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth A. (2020) Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine. Drug Metabolism and Disposition, 48 (4). ISSN 0090-9556 (Print), 1521-009X (Online) (doi:https://doi.org/10.1124/dmd.119.089995)

FMO5

Gonzalez Malagon, Sandra G., Melidoni, Anna N., Hernandez, Diana, Omar, Bilal A., Houseman, Lyndsey, Veeravalli, Sunil, Scott, Flora, Varshavi, Dorsa, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Tsuchiya, Yugo, Timms, John F., Phillips, Ian R. and Shephard, Elizabeth A. (2015) The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing. Biochemical Pharmacology, 96 (3). pp. 267-277. ISSN 0006-2952 (doi:https://doi.org/10.1016/j.bcp.2015.05.013)

FMO5 KO

Scott, Flora H., Varshavi, Dorsa, Veeravalli, Sunil, Phillips, Ian R., Veselkov, Kirill, Strittmatter, Nicole, Takats, Zoltan, Shephard, Elizabeth A. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2018) Metabolic biomarkers of ageing in C57BL/6J wild-type and flavin-containing monooxygenase 5 (FMO5)-knockout mice. Frontiers in Molecular Biosciences, 5:28. ISSN 2296-889X (Online) (doi:https://doi.org/10.3389/fmolb.2018.00028)

genetic knock-out

Gonzalez Malagon, Sandra G., Melidoni, Anna N., Hernandez, Diana, Omar, Bilal A., Houseman, Lyndsey, Veeravalli, Sunil, Scott, Flora, Varshavi, Dorsa, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Tsuchiya, Yugo, Timms, John F., Phillips, Ian R. and Shephard, Elizabeth A. (2015) The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing. Biochemical Pharmacology, 96 (3). pp. 267-277. ISSN 0006-2952 (doi:https://doi.org/10.1016/j.bcp.2015.05.013)

glucose

Gonzalez Malagon, Sandra G., Melidoni, Anna N., Hernandez, Diana, Omar, Bilal A., Houseman, Lyndsey, Veeravalli, Sunil, Scott, Flora, Varshavi, Dorsa, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Tsuchiya, Yugo, Timms, John F., Phillips, Ian R. and Shephard, Elizabeth A. (2015) The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing. Biochemical Pharmacology, 96 (3). pp. 267-277. ISSN 0006-2952 (doi:https://doi.org/10.1016/j.bcp.2015.05.013)

gut microbiome

Veeravalli, Sunil, Varshavi, Dorsa, Scott, Flora H, Varshavi, Dorna, Pullen, Francis, Veselkov, Kirill, Phillips, Ian R, Everett, Jeremy ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth (2022) Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5-/- mice, decreases plasma cholesterol and epididymal fat deposition. Frontiers in Physiology, 13:859681. pp. 1-13. ISSN 1664-042X (Online) (doi:https://doi.org/10.3389/fphys.2022.859681)

HCT116

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-021-01852-w)

humans

Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth A. (2020) Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine. Drug Metabolism and Disposition, 48 (4). ISSN 0090-9556 (Print), 1521-009X (Online) (doi:https://doi.org/10.1124/dmd.119.089995)

hypotaurine

Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth A. (2020) Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine. Drug Metabolism and Disposition, 48 (4). ISSN 0090-9556 (Print), 1521-009X (Online) (doi:https://doi.org/10.1124/dmd.119.089995)

KRAS

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-021-01852-w)

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-020-01674-2)

malic enzyme 1

Gonzalez Malagon, Sandra G., Melidoni, Anna N., Hernandez, Diana, Omar, Bilal A., Houseman, Lyndsey, Veeravalli, Sunil, Scott, Flora, Varshavi, Dorsa, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Tsuchiya, Yugo, Timms, John F., Phillips, Ian R. and Shephard, Elizabeth A. (2015) The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing. Biochemical Pharmacology, 96 (3). pp. 267-277. ISSN 0006-2952 (doi:https://doi.org/10.1016/j.bcp.2015.05.013)

medicine

Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth A. (2020) Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine. Drug Metabolism and Disposition, 48 (4). ISSN 0090-9556 (Print), 1521-009X (Online) (doi:https://doi.org/10.1124/dmd.119.089995)

metabolic profiling

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-021-01852-w)

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-020-01674-2)

Varshavi, Dorsa, Varshavi, Dorna and Everett, Jeremy ORCID: 0000-0003-1550-4482 (2016) The role of pharmacometabonomics in predicting drug pharmacokinetics. International Journal of Pharmacokinetics, 1 (1). pp. 5-8. ISSN 2053-0846 (Print), 2053-0854 (Online) (doi:https://doi.org/10.4155/ipk-2016-0010)

Gonzalez Malagon, Sandra G., Melidoni, Anna N., Hernandez, Diana, Omar, Bilal A., Houseman, Lyndsey, Veeravalli, Sunil, Scott, Flora, Varshavi, Dorsa, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Tsuchiya, Yugo, Timms, John F., Phillips, Ian R. and Shephard, Elizabeth A. (2015) The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing. Biochemical Pharmacology, 96 (3). pp. 267-277. ISSN 0006-2952 (doi:https://doi.org/10.1016/j.bcp.2015.05.013)

metabolite

Veeravalli, Sunil, Varshavi, Dorsa, Scott, Flora H, Varshavi, Dorna, Pullen, Francis, Veselkov, Kirill, Phillips, Ian R, Everett, Jeremy ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth (2022) Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5-/- mice, decreases plasma cholesterol and epididymal fat deposition. Frontiers in Physiology, 13:859681. pp. 1-13. ISSN 1664-042X (Online) (doi:https://doi.org/10.3389/fphys.2022.859681)

Metabolite identification

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Dona, Anthony C., Kyriakides, Michael, Scott, Flora, Shephard, Elizabeth A., Varshavi, Dorsa and Veselkov, Kirill (2016) A guide to the identification of metabolites in NMR-based metabonomics/metabolomics experiments. Computational and Structural Biotechnology Journal, 14. pp. 135-153. ISSN 2001-0370 (Print), 2001-0370 (Online) (doi:https://doi.org/10.1016/j.csbj.2016.02.005)

metabolomics

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-021-01852-w)

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-020-01674-2)

Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth A. (2020) Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine. Drug Metabolism and Disposition, 48 (4). ISSN 0090-9556 (Print), 1521-009X (Online) (doi:https://doi.org/10.1124/dmd.119.089995)

Scott, Flora H., Varshavi, Dorsa, Veeravalli, Sunil, Phillips, Ian R., Veselkov, Kirill, Strittmatter, Nicole, Takats, Zoltan, Shephard, Elizabeth A. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2018) Metabolic biomarkers of ageing in C57BL/6J wild-type and flavin-containing monooxygenase 5 (FMO5)-knockout mice. Frontiers in Molecular Biosciences, 5:28. ISSN 2296-889X (Online) (doi:https://doi.org/10.3389/fmolb.2018.00028)

Varshavi, Dorsa, Varshavi, Dorna and Everett, Jeremy ORCID: 0000-0003-1550-4482 (2016) The role of pharmacometabonomics in predicting drug pharmacokinetics. International Journal of Pharmacokinetics, 1 (1). pp. 5-8. ISSN 2053-0846 (Print), 2053-0854 (Online) (doi:https://doi.org/10.4155/ipk-2016-0010)

metabonomics

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-021-01852-w)

Everett, Jeremy, Varshavi, Dorsa, Shephard, Elizabeth, and Veeravalli, Sunil (2021) Patent - Treatment of obesity and related conditions. .

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-020-01674-2)

Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth A. (2020) Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine. Drug Metabolism and Disposition, 48 (4). ISSN 0090-9556 (Print), 1521-009X (Online) (doi:https://doi.org/10.1124/dmd.119.089995)

Scott, Flora H., Varshavi, Dorsa, Veeravalli, Sunil, Phillips, Ian R., Veselkov, Kirill, Strittmatter, Nicole, Takats, Zoltan, Shephard, Elizabeth A. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2018) Metabolic biomarkers of ageing in C57BL/6J wild-type and flavin-containing monooxygenase 5 (FMO5)-knockout mice. Frontiers in Molecular Biosciences, 5:28. ISSN 2296-889X (Online) (doi:https://doi.org/10.3389/fmolb.2018.00028)

Varshavi, Dorsa, Varshavi, Dorna and Everett, Jeremy ORCID: 0000-0003-1550-4482 (2016) The role of pharmacometabonomics in predicting drug pharmacokinetics. International Journal of Pharmacokinetics, 1 (1). pp. 5-8. ISSN 2053-0846 (Print), 2053-0854 (Online) (doi:https://doi.org/10.4155/ipk-2016-0010)

Gonzalez Malagon, Sandra G., Melidoni, Anna N., Hernandez, Diana, Omar, Bilal A., Houseman, Lyndsey, Veeravalli, Sunil, Scott, Flora, Varshavi, Dorsa, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Tsuchiya, Yugo, Timms, John F., Phillips, Ian R. and Shephard, Elizabeth A. (2015) The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing. Biochemical Pharmacology, 96 (3). pp. 267-277. ISSN 0006-2952 (doi:https://doi.org/10.1016/j.bcp.2015.05.013)

Metabonomics etabolomics

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Dona, Anthony C., Kyriakides, Michael, Scott, Flora, Shephard, Elizabeth A., Varshavi, Dorsa and Veselkov, Kirill (2016) A guide to the identification of metabolites in NMR-based metabonomics/metabolomics experiments. Computational and Structural Biotechnology Journal, 14. pp. 135-153. ISSN 2001-0370 (Print), 2001-0370 (Online) (doi:https://doi.org/10.1016/j.csbj.2016.02.005)

Molecular structure

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Dona, Anthony C., Kyriakides, Michael, Scott, Flora, Shephard, Elizabeth A., Varshavi, Dorsa and Veselkov, Kirill (2016) A guide to the identification of metabolites in NMR-based metabonomics/metabolomics experiments. Computational and Structural Biotechnology Journal, 14. pp. 135-153. ISSN 2001-0370 (Print), 2001-0370 (Online) (doi:https://doi.org/10.1016/j.csbj.2016.02.005)

mouse

Everett, Jeremy, Varshavi, Dorsa, Shephard, Elizabeth, and Veeravalli, Sunil (2021) Patent - Treatment of obesity and related conditions. .

mutations

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-021-01852-w)

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-020-01674-2)

NMR

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-021-01852-w)

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-020-01674-2)

NMR (nuclear magnetic resonance) spectroscopy

Veeravalli, Sunil, Varshavi, Dorsa, Scott, Flora H, Varshavi, Dorna, Pullen, Francis, Veselkov, Kirill, Phillips, Ian R, Everett, Jeremy ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth (2022) Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5-/- mice, decreases plasma cholesterol and epididymal fat deposition. Frontiers in Physiology, 13:859681. pp. 1-13. ISSN 1664-042X (Online) (doi:https://doi.org/10.3389/fphys.2022.859681)

Nuclear magnetic resonance (NMR) spectroscopy

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Dona, Anthony C., Kyriakides, Michael, Scott, Flora, Shephard, Elizabeth A., Varshavi, Dorsa and Veselkov, Kirill (2016) A guide to the identification of metabolites in NMR-based metabonomics/metabolomics experiments. Computational and Structural Biotechnology Journal, 14. pp. 135-153. ISSN 2001-0370 (Print), 2001-0370 (Online) (doi:https://doi.org/10.1016/j.csbj.2016.02.005)

Pharmacometabolomics

Varshavi, Dorsa, Varshavi, Dorna and Everett, Jeremy ORCID: 0000-0003-1550-4482 (2016) The role of pharmacometabonomics in predicting drug pharmacokinetics. International Journal of Pharmacokinetics, 1 (1). pp. 5-8. ISSN 2053-0846 (Print), 2053-0854 (Online) (doi:https://doi.org/10.4155/ipk-2016-0010)

Pharmacometabonomics

Varshavi, Dorsa, Varshavi, Dorna and Everett, Jeremy ORCID: 0000-0003-1550-4482 (2016) The role of pharmacometabonomics in predicting drug pharmacokinetics. International Journal of Pharmacokinetics, 1 (1). pp. 5-8. ISSN 2053-0846 (Print), 2053-0854 (Online) (doi:https://doi.org/10.4155/ipk-2016-0010)

plasma

Scott, Flora H., Varshavi, Dorsa, Veeravalli, Sunil, Phillips, Ian R., Veselkov, Kirill, Strittmatter, Nicole, Takats, Zoltan, Shephard, Elizabeth A. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2018) Metabolic biomarkers of ageing in C57BL/6J wild-type and flavin-containing monooxygenase 5 (FMO5)-knockout mice. Frontiers in Molecular Biosciences, 5:28. ISSN 2296-889X (Online) (doi:https://doi.org/10.3389/fmolb.2018.00028)

Prediction of PK

Varshavi, Dorsa, Varshavi, Dorna and Everett, Jeremy ORCID: 0000-0003-1550-4482 (2016) The role of pharmacometabonomics in predicting drug pharmacokinetics. International Journal of Pharmacokinetics, 1 (1). pp. 5-8. ISSN 2053-0846 (Print), 2053-0854 (Online) (doi:https://doi.org/10.4155/ipk-2016-0010)

stomach

Veeravalli, Sunil, Varshavi, Dorsa, Scott, Flora H, Varshavi, Dorna, Pullen, Francis, Veselkov, Kirill, Phillips, Ian R, Everett, Jeremy ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth (2022) Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5-/- mice, decreases plasma cholesterol and epididymal fat deposition. Frontiers in Physiology, 13:859681. pp. 1-13. ISSN 1664-042X (Online) (doi:https://doi.org/10.3389/fphys.2022.859681)

SW48

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-020-01674-2)

taurine

Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth A. (2020) Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine. Drug Metabolism and Disposition, 48 (4). ISSN 0090-9556 (Print), 1521-009X (Online) (doi:https://doi.org/10.1124/dmd.119.089995)

urine

Veeravalli, Sunil, Varshavi, Dorsa, Scott, Flora H, Varshavi, Dorna, Pullen, Francis, Veselkov, Kirill, Phillips, Ian R, Everett, Jeremy ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth (2022) Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5-/- mice, decreases plasma cholesterol and epididymal fat deposition. Frontiers in Physiology, 13:859681. pp. 1-13. ISSN 1664-042X (Online) (doi:https://doi.org/10.3389/fphys.2022.859681)

Scott, Flora H., Varshavi, Dorsa, Veeravalli, Sunil, Phillips, Ian R., Veselkov, Kirill, Strittmatter, Nicole, Takats, Zoltan, Shephard, Elizabeth A. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2018) Metabolic biomarkers of ageing in C57BL/6J wild-type and flavin-containing monooxygenase 5 (FMO5)-knockout mice. Frontiers in Molecular Biosciences, 5:28. ISSN 2296-889X (Online) (doi:https://doi.org/10.3389/fmolb.2018.00028)

white adipose tissue

Gonzalez Malagon, Sandra G., Melidoni, Anna N., Hernandez, Diana, Omar, Bilal A., Houseman, Lyndsey, Veeravalli, Sunil, Scott, Flora, Varshavi, Dorsa, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Tsuchiya, Yugo, Timms, John F., Phillips, Ian R. and Shephard, Elizabeth A. (2015) The phenotype of a knockout mouse identifies flavin-containing monooxygenase 5 (FMO5) as a regulator of metabolic ageing. Biochemical Pharmacology, 96 (3). pp. 267-277. ISSN 0006-2952 (doi:https://doi.org/10.1016/j.bcp.2015.05.013)

This list was generated on Tue Apr 23 10:56:35 2024 UTC.