Items where Author is "Thurston, David E."
C7-sibirosamine sugar
Jackson, Paul J. M., James, Colin H., Jenkins, Terence C., Rahman, Khondaker C. and Thurston, David E. (2014) Computational studies support the role of the C7-sibirosamine sugar of the pyrrolobenzodiazepine (PBD) sibiromycin in transcription factor inhibition. ACS Chemical Biology, 9 (10). pp. 2432-2440. ISSN 1554-8929 (Print), 1554-8937 (Online) (doi:10.1021/cb5002203)
computational studies support
Jackson, Paul J. M., James, Colin H., Jenkins, Terence C., Rahman, Khondaker C. and Thurston, David E. (2014) Computational studies support the role of the C7-sibirosamine sugar of the pyrrolobenzodiazepine (PBD) sibiromycin in transcription factor inhibition. ACS Chemical Biology, 9 (10). pp. 2432-2440. ISSN 1554-8929 (Print), 1554-8937 (Online) (doi:10.1021/cb5002203)
inverted CCAAT box
Brucoli, Federico, Hawkins, Rachel M., James, Colin H., Wells, Geoff, Jenkins, Terrence C., Ellis, Tom, Hartley, John A., Howard, Philip W. and Thurston, David E. (2011) Novel C8-linked pyrrolobenzodiazepine (PBD)-heterocycle conjugates that recognize DNA sequences containing an inverted CCAAT box. Bioorganic & Medicinal Chemistry Letters, 21. pp. 3780-3783. ISSN 0960-894X (online) (doi:10.1016/j.bmcl.2011.04.054)
nticancer agents
Brucoli, Federico, Hawkins, Rachel M., James, Colin H., Wells, Geoff, Jenkins, Terrence C., Ellis, Tom, Hartley, John A., Howard, Philip W. and Thurston, David E. (2011) Novel C8-linked pyrrolobenzodiazepine (PBD)-heterocycle conjugates that recognize DNA sequences containing an inverted CCAAT box. Bioorganic & Medicinal Chemistry Letters, 21. pp. 3780-3783. ISSN 0960-894X (online) (doi:10.1016/j.bmcl.2011.04.054)
nuclear factor Y
Brucoli, Federico, Hawkins, Rachel M., James, Colin H., Wells, Geoff, Jenkins, Terrence C., Ellis, Tom, Hartley, John A., Howard, Philip W. and Thurston, David E. (2011) Novel C8-linked pyrrolobenzodiazepine (PBD)-heterocycle conjugates that recognize DNA sequences containing an inverted CCAAT box. Bioorganic & Medicinal Chemistry Letters, 21. pp. 3780-3783. ISSN 0960-894X (online) (doi:10.1016/j.bmcl.2011.04.054)
pyrrolobenzodiazepine (PBD) sibiromycin
Jackson, Paul J. M., James, Colin H., Jenkins, Terence C., Rahman, Khondaker C. and Thurston, David E. (2014) Computational studies support the role of the C7-sibirosamine sugar of the pyrrolobenzodiazepine (PBD) sibiromycin in transcription factor inhibition. ACS Chemical Biology, 9 (10). pp. 2432-2440. ISSN 1554-8929 (Print), 1554-8937 (Online) (doi:10.1021/cb5002203)
pyrrolobenzodiazepine (PBD)-conjugate
Brucoli, Federico, Hawkins, Rachel M., James, Colin H., Wells, Geoff, Jenkins, Terrence C., Ellis, Tom, Hartley, John A., Howard, Philip W. and Thurston, David E. (2011) Novel C8-linked pyrrolobenzodiazepine (PBD)-heterocycle conjugates that recognize DNA sequences containing an inverted CCAAT box. Bioorganic & Medicinal Chemistry Letters, 21. pp. 3780-3783. ISSN 0960-894X (online) (doi:10.1016/j.bmcl.2011.04.054)
topoisomerase IIa
Brucoli, Federico, Hawkins, Rachel M., James, Colin H., Wells, Geoff, Jenkins, Terrence C., Ellis, Tom, Hartley, John A., Howard, Philip W. and Thurston, David E. (2011) Novel C8-linked pyrrolobenzodiazepine (PBD)-heterocycle conjugates that recognize DNA sequences containing an inverted CCAAT box. Bioorganic & Medicinal Chemistry Letters, 21. pp. 3780-3783. ISSN 0960-894X (online) (doi:10.1016/j.bmcl.2011.04.054)
transcription factor inhibition
Jackson, Paul J. M., James, Colin H., Jenkins, Terence C., Rahman, Khondaker C. and Thurston, David E. (2014) Computational studies support the role of the C7-sibirosamine sugar of the pyrrolobenzodiazepine (PBD) sibiromycin in transcription factor inhibition. ACS Chemical Biology, 9 (10). pp. 2432-2440. ISSN 1554-8929 (Print), 1554-8937 (Online) (doi:10.1021/cb5002203)