Items where Author is "Scott, S.D."
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breast cancer
Greco, O., Joiner, M.C., Doleh, A., Powell, A.D., Hillman, G. and Scott, S.D. (2006) Hypoxia- and radiation-activated Cre/loxP 'molecular switch' vectors for gene therapy of cancer. Gene Therapy, 13 (3). pp. 206-215. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3302640)
bystander effect
Greco, O., Joiner, M.C., Doleh, A. and Scott, S.D. (2005) VP22-mediated intercellular transport for suicide gene therapy under oxic and hypoxic conditions. Gene Therapy, 12 (12). pp. 974-979. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3302482)
cancer
Greco, O., Scott, S.D., Marples, B. and Dachs, D.U. (2002) Cancer gene therapy: 'delivery, delivery, delivery'. Frontiers in Bioscience, 7. d1516-d1524. ISSN 1093-9946 (Print), 1093-4715 (Online) (doi:https://doi.org/10.2741/greco)
Scott, S.D. and Marples, B. (2000) Comment on the use of the cre/loxP recombinase system for gene therapy vectors. Gene Therapy, 7 (19). p. 1706. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301305)
CArG
Greco, O., Joiner, M.C., Doleh, A., Powell, A.D., Hillman, G. and Scott, S.D. (2006) Hypoxia- and radiation-activated Cre/loxP 'molecular switch' vectors for gene therapy of cancer. Gene Therapy, 13 (3). pp. 206-215. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3302640)
CArG element
Greco, O., Marples, B., Dachs, G.U., Williams, K.J., Patterson, A.V. and Scott, S.D. (2002) Novel chimeric gene promoters responsive to hypoxia and ionizing radiation. Gene Therapy, 9 (20). pp. 1403-1411. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301823)
carg elements
Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2003) Radiogenetic therapy: strategies to overcome tumor resistance. Current Pharmaceutical Design, 9 (26). pp. 2105-2112. ISSN 1381-6128 (Print), 1873-4286 (Online) (doi:https://doi.org/10.2174/1381612033454090)
Scott, S.D., Joiner, M.C. and Marples, B (2002) Optimizing radiation-responsive gene promoters for radiogenetic cancer therapy. Gene Therapy, 9 (20). pp. 1396-1402. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301822)
Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2002) Molecular approaches to chemo-radiotherapy. European Journal of Cancer, 38 (2). pp. 231-239. ISSN 0959-8049 (doi:https://doi.org/10.1016/S0959-8049(01)00367-7)
Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2002) Molecular approaches to chemo-radiotherapy. European Journal of Cancer, 38 (2). pp. 231-239. ISSN 0959-8049 (doi:https://doi.org/10.1016/S0959-8049(01)00367-7)
Marples, B., Scott, S.D., Hendry, J.H., Embleton, M.J., Lashford, L.S. and Margison, G.P. (2000) Development of synthetic promoters for radiationmediated gene therapy. Gene Therapy, 7 (6). pp. 511-517. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301116)
cell-based
Muthana, M., Scott, S.D., Farrow, N., Morrow, F., Murdoch, C., Grubb, S., Brown, N., Dobson, J. and Lewis, C.E. (2008) A novel magnetic approach to enhance the efficacy of cell-based gene therapies. Gene Therapy, 15 (12). pp. 902-910. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/gt.2008.57)
CMV promoter
Scott, S.D. and Marples, B. (2000) Comment on the use of the cre/loxP recombinase system for gene therapy vectors. Gene Therapy, 7 (19). p. 1706. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301305)
CRE recombinase
Scott, S.D., Marples, B., Hendry, J.H., Lashford, L.S., Embleton, M.J., Hunter, R.D., Howell, A. and Margison, G.P. (2000) A radiation-controlled molecular switch for use in gene therapy of cancer. Gene Therapy, 7 (13). pp. 1121-1125. (doi:https://doi.org/10.1038/sj.gt.3301223)
cre/loxP
Scott, S.D. and Marples, B. (2000) Comment on the use of the cre/loxP recombinase system for gene therapy vectors. Gene Therapy, 7 (19). p. 1706. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301305)
DNA
Scott, S.D. and Marples, B. (2000) Comment on the use of the cre/loxP recombinase system for gene therapy vectors. Gene Therapy, 7 (19). p. 1706. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301305)
Egr1
Marples, B., Scott, S.D., Hendry, J.H., Embleton, M.J., Lashford, L.S. and Margison, G.P. (2000) Development of synthetic promoters for radiationmediated gene therapy. Gene Therapy, 7 (6). pp. 511-517. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301116)
fusion proteins
Greco, O., Joiner, M.C., Doleh, A. and Scott, S.D. (2005) VP22-mediated intercellular transport for suicide gene therapy under oxic and hypoxic conditions. Gene Therapy, 12 (12). pp. 974-979. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3302482)
ganciclovir
Scott, S.D., Marples, B., Hendry, J.H., Lashford, L.S., Embleton, M.J., Hunter, R.D., Howell, A. and Margison, G.P. (2000) A radiation-controlled molecular switch for use in gene therapy of cancer. Gene Therapy, 7 (13). pp. 1121-1125. (doi:https://doi.org/10.1038/sj.gt.3301223)
GCV
Greco, O., Joiner, M.C., Doleh, A. and Scott, S.D. (2005) VP22-mediated intercellular transport for suicide gene therapy under oxic and hypoxic conditions. Gene Therapy, 12 (12). pp. 974-979. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3302482)
gdept
Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2003) Radiogenetic therapy: strategies to overcome tumor resistance. Current Pharmaceutical Design, 9 (26). pp. 2105-2112. ISSN 1381-6128 (Print), 1873-4286 (Online) (doi:https://doi.org/10.2174/1381612033454090)
Greco, O., Marples, B., Dachs, G.U., Williams, K.J., Patterson, A.V. and Scott, S.D. (2002) Novel chimeric gene promoters responsive to hypoxia and ionizing radiation. Gene Therapy, 9 (20). pp. 1403-1411. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301823)
Scott, S.D., Joiner, M.C. and Marples, B (2002) Optimizing radiation-responsive gene promoters for radiogenetic cancer therapy. Gene Therapy, 9 (20). pp. 1396-1402. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301822)
Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2002) Molecular approaches to chemo-radiotherapy. European Journal of Cancer, 38 (2). pp. 231-239. ISSN 0959-8049 (doi:https://doi.org/10.1016/S0959-8049(01)00367-7)
Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2002) Molecular approaches to chemo-radiotherapy. European Journal of Cancer, 38 (2). pp. 231-239. ISSN 0959-8049 (doi:https://doi.org/10.1016/S0959-8049(01)00367-7)
gene therapy
Muthana, M., Scott, S.D., Farrow, N., Morrow, F., Murdoch, C., Grubb, S., Brown, N., Dobson, J. and Lewis, C.E. (2008) A novel magnetic approach to enhance the efficacy of cell-based gene therapies. Gene Therapy, 15 (12). pp. 902-910. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/gt.2008.57)
Greco, O., Marples, B., Wilson, G.D., Joiner, M.C. and Scott, S.D. (2005) Radiation-induced gene therapy. Radiation Research, 163 (6). pp. 707-708. ISSN 0033-7587 (Print), 1938-5404 (Online) (doi:https://doi.org/10.1667/RR3300)
Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2003) Radiogenetic therapy: strategies to overcome tumor resistance. Current Pharmaceutical Design, 9 (26). pp. 2105-2112. ISSN 1381-6128 (Print), 1873-4286 (Online) (doi:https://doi.org/10.2174/1381612033454090)
Greco, O., Scott, S.D., Marples, B. and Dachs, D.U. (2002) Cancer gene therapy: 'delivery, delivery, delivery'. Frontiers in Bioscience, 7. d1516-d1524. ISSN 1093-9946 (Print), 1093-4715 (Online) (doi:https://doi.org/10.2741/greco)
Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2002) Molecular approaches to chemo-radiotherapy. European Journal of Cancer, 38 (2). pp. 231-239. ISSN 0959-8049 (doi:https://doi.org/10.1016/S0959-8049(01)00367-7)
Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2002) Molecular approaches to chemo-radiotherapy. European Journal of Cancer, 38 (2). pp. 231-239. ISSN 0959-8049 (doi:https://doi.org/10.1016/S0959-8049(01)00367-7)
Scott, S.D. and Marples, B. (2000) Comment on the use of the cre/loxP recombinase system for gene therapy vectors. Gene Therapy, 7 (19). p. 1706. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301305)
Marples, B., Scott, S.D., Hendry, J.H., Embleton, M.J., Lashford, L.S. and Margison, G.P. (2000) Development of synthetic promoters for radiationmediated gene therapy. Gene Therapy, 7 (6). pp. 511-517. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301116)
gene vector
Collis, S.J., Tighe, A., Scott, S.D., Roberts, S.A., Hendry, J.H. and Margison, G.P. (2001) Ribozyme minigene-mediated RAD51 down-regulation increases radiosensitivity of human prostate cancer cells. Nucleic Acids Research, 29 (7). pp. 1534-1538. ISSN 0305-1048 (Print), 1362-4962 (Online) (doi:https://doi.org/10.1093/nar/29.7.1534)
GFP
Greco, O., Joiner, M.C., Doleh, A., Powell, A.D., Hillman, G. and Scott, S.D. (2006) Hypoxia- and radiation-activated Cre/loxP 'molecular switch' vectors for gene therapy of cancer. Gene Therapy, 13 (3). pp. 206-215. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3302640)
Greco, O., Joiner, M.C., Doleh, A. and Scott, S.D. (2005) VP22-mediated intercellular transport for suicide gene therapy under oxic and hypoxic conditions. Gene Therapy, 12 (12). pp. 974-979. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3302482)
Marples, B., Scott, S.D., Hendry, J.H., Embleton, M.J., Lashford, L.S. and Margison, G.P. (2000) Development of synthetic promoters for radiationmediated gene therapy. Gene Therapy, 7 (6). pp. 511-517. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301116)
glioma
Greco, O., Joiner, M.C., Doleh, A., Powell, A.D., Hillman, G. and Scott, S.D. (2006) Hypoxia- and radiation-activated Cre/loxP 'molecular switch' vectors for gene therapy of cancer. Gene Therapy, 13 (3). pp. 206-215. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3302640)
Greco, O., Joiner, M.C., Doleh, A. and Scott, S.D. (2005) VP22-mediated intercellular transport for suicide gene therapy under oxic and hypoxic conditions. Gene Therapy, 12 (12). pp. 974-979. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3302482)
HRE
Greco, O., Joiner, M.C., Doleh, A., Powell, A.D., Hillman, G. and Scott, S.D. (2006) Hypoxia- and radiation-activated Cre/loxP 'molecular switch' vectors for gene therapy of cancer. Gene Therapy, 13 (3). pp. 206-215. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3302640)
Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2003) Radiogenetic therapy: strategies to overcome tumor resistance. Current Pharmaceutical Design, 9 (26). pp. 2105-2112. ISSN 1381-6128 (Print), 1873-4286 (Online) (doi:https://doi.org/10.2174/1381612033454090)
Greco, O., Marples, B., Dachs, G.U., Williams, K.J., Patterson, A.V. and Scott, S.D. (2002) Novel chimeric gene promoters responsive to hypoxia and ionizing radiation. Gene Therapy, 9 (20). pp. 1403-1411. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301823)
HRP/IAA
Greco, O., Marples, B., Dachs, G.U., Williams, K.J., Patterson, A.V. and Scott, S.D. (2002) Novel chimeric gene promoters responsive to hypoxia and ionizing radiation. Gene Therapy, 9 (20). pp. 1403-1411. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301823)
HSVtk
Greco, O., Joiner, M.C., Doleh, A. and Scott, S.D. (2005) VP22-mediated intercellular transport for suicide gene therapy under oxic and hypoxic conditions. Gene Therapy, 12 (12). pp. 974-979. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3302482)
Scott, S.D., Marples, B., Hendry, J.H., Lashford, L.S., Embleton, M.J., Hunter, R.D., Howell, A. and Margison, G.P. (2000) A radiation-controlled molecular switch for use in gene therapy of cancer. Gene Therapy, 7 (13). pp. 1121-1125. (doi:https://doi.org/10.1038/sj.gt.3301223)
HSVtk/GCV
Greco, O., Joiner, M.C., Doleh, A., Powell, A.D., Hillman, G. and Scott, S.D. (2006) Hypoxia- and radiation-activated Cre/loxP 'molecular switch' vectors for gene therapy of cancer. Gene Therapy, 13 (3). pp. 206-215. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3302640)
hypoxia
Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2003) Radiogenetic therapy: strategies to overcome tumor resistance. Current Pharmaceutical Design, 9 (26). pp. 2105-2112. ISSN 1381-6128 (Print), 1873-4286 (Online) (doi:https://doi.org/10.2174/1381612033454090)
Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2002) Molecular approaches to chemo-radiotherapy. European Journal of Cancer, 38 (2). pp. 231-239. ISSN 0959-8049 (doi:https://doi.org/10.1016/S0959-8049(01)00367-7)
Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2002) Molecular approaches to chemo-radiotherapy. European Journal of Cancer, 38 (2). pp. 231-239. ISSN 0959-8049 (doi:https://doi.org/10.1016/S0959-8049(01)00367-7)
magnetic
Muthana, M., Scott, S.D., Farrow, N., Morrow, F., Murdoch, C., Grubb, S., Brown, N., Dobson, J. and Lewis, C.E. (2008) A novel magnetic approach to enhance the efficacy of cell-based gene therapies. Gene Therapy, 15 (12). pp. 902-910. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/gt.2008.57)
molecular switch
Scott, S.D. and Marples, B. (2000) Comment on the use of the cre/loxP recombinase system for gene therapy vectors. Gene Therapy, 7 (19). p. 1706. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301305)
Scott, S.D., Marples, B., Hendry, J.H., Lashford, L.S., Embleton, M.J., Hunter, R.D., Howell, A. and Margison, G.P. (2000) A radiation-controlled molecular switch for use in gene therapy of cancer. Gene Therapy, 7 (13). pp. 1121-1125. (doi:https://doi.org/10.1038/sj.gt.3301223)
promoters
Scott, S.D., Joiner, M.C. and Marples, B (2002) Optimizing radiation-responsive gene promoters for radiogenetic cancer therapy. Gene Therapy, 9 (20). pp. 1396-1402. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301822)
Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2002) Molecular approaches to chemo-radiotherapy. European Journal of Cancer, 38 (2). pp. 231-239. ISSN 0959-8049 (doi:https://doi.org/10.1016/S0959-8049(01)00367-7)
Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2002) Molecular approaches to chemo-radiotherapy. European Journal of Cancer, 38 (2). pp. 231-239. ISSN 0959-8049 (doi:https://doi.org/10.1016/S0959-8049(01)00367-7)
prostate
Collis, S.J., Tighe, A., Scott, S.D., Roberts, S.A., Hendry, J.H. and Margison, G.P. (2001) Ribozyme minigene-mediated RAD51 down-regulation increases radiosensitivity of human prostate cancer cells. Nucleic Acids Research, 29 (7). pp. 1534-1538. ISSN 0305-1048 (Print), 1362-4962 (Online) (doi:https://doi.org/10.1093/nar/29.7.1534)
RAD51
Collis, S.J., Tighe, A., Scott, S.D., Roberts, S.A., Hendry, J.H. and Margison, G.P. (2001) Ribozyme minigene-mediated RAD51 down-regulation increases radiosensitivity of human prostate cancer cells. Nucleic Acids Research, 29 (7). pp. 1534-1538. ISSN 0305-1048 (Print), 1362-4962 (Online) (doi:https://doi.org/10.1093/nar/29.7.1534)
radiation
Greco, O., Marples, B., Wilson, G.D., Joiner, M.C. and Scott, S.D. (2005) Radiation-induced gene therapy. Radiation Research, 163 (6). pp. 707-708. ISSN 0033-7587 (Print), 1938-5404 (Online) (doi:https://doi.org/10.1667/RR3300)
Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2003) Radiogenetic therapy: strategies to overcome tumor resistance. Current Pharmaceutical Design, 9 (26). pp. 2105-2112. ISSN 1381-6128 (Print), 1873-4286 (Online) (doi:https://doi.org/10.2174/1381612033454090)
Scott, S.D., Joiner, M.C. and Marples, B (2002) Optimizing radiation-responsive gene promoters for radiogenetic cancer therapy. Gene Therapy, 9 (20). pp. 1396-1402. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301822)
Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2002) Molecular approaches to chemo-radiotherapy. European Journal of Cancer, 38 (2). pp. 231-239. ISSN 0959-8049 (doi:https://doi.org/10.1016/S0959-8049(01)00367-7)
Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2002) Molecular approaches to chemo-radiotherapy. European Journal of Cancer, 38 (2). pp. 231-239. ISSN 0959-8049 (doi:https://doi.org/10.1016/S0959-8049(01)00367-7)
Collis, S.J., Tighe, A., Scott, S.D., Roberts, S.A., Hendry, J.H. and Margison, G.P. (2001) Ribozyme minigene-mediated RAD51 down-regulation increases radiosensitivity of human prostate cancer cells. Nucleic Acids Research, 29 (7). pp. 1534-1538. ISSN 0305-1048 (Print), 1362-4962 (Online) (doi:https://doi.org/10.1093/nar/29.7.1534)
radiation-responsive elements
Scott, S.D., Marples, B., Hendry, J.H., Lashford, L.S., Embleton, M.J., Hunter, R.D., Howell, A. and Margison, G.P. (2000) A radiation-controlled molecular switch for use in gene therapy of cancer. Gene Therapy, 7 (13). pp. 1121-1125. (doi:https://doi.org/10.1038/sj.gt.3301223)
radiotherapy
Greco, O., Marples, B., Dachs, G.U., Williams, K.J., Patterson, A.V. and Scott, S.D. (2002) Novel chimeric gene promoters responsive to hypoxia and ionizing radiation. Gene Therapy, 9 (20). pp. 1403-1411. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301823)
Scott, S.D., Marples, B., Hendry, J.H., Lashford, L.S., Embleton, M.J., Hunter, R.D., Howell, A. and Margison, G.P. (2000) A radiation-controlled molecular switch for use in gene therapy of cancer. Gene Therapy, 7 (13). pp. 1121-1125. (doi:https://doi.org/10.1038/sj.gt.3301223)
SRF
Scott, S.D., Joiner, M.C. and Marples, B (2002) Optimizing radiation-responsive gene promoters for radiogenetic cancer therapy. Gene Therapy, 9 (20). pp. 1396-1402. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301822)
tumour
Collis, S.J., Tighe, A., Scott, S.D., Roberts, S.A., Hendry, J.H. and Margison, G.P. (2001) Ribozyme minigene-mediated RAD51 down-regulation increases radiosensitivity of human prostate cancer cells. Nucleic Acids Research, 29 (7). pp. 1534-1538. ISSN 0305-1048 (Print), 1362-4962 (Online) (doi:https://doi.org/10.1093/nar/29.7.1534)