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Adam, Till J ORCID: https://orcid.org/0009-0004-6609-3462, Thompson, Trevor ORCID: https://orcid.org/0000-0001-9880-782X, Peroz, Fabiola H ORCID: https://orcid.org/0000-0003-2798-580X, Heisig, Jan P ORCID: https://orcid.org/0000-0001-8228-1907, Gellert, Paul ORCID: https://orcid.org/0000-0001-7492-7210, Alonso-Perez, Enrique ORCID: https://orcid.org/0000-0002-0228-5084, Bister, Lara ORCID: https://orcid.org/0000-0001-5915-757X, Thygesen, Lau Caspar ORCID: https://orcid.org/0000-0001-8375-5211, Conus, Philippe ORCID: https://orcid.org/0000-0002-5832-1910, von Känel, Roland ORCID: https://orcid.org/0000-0002-8929-5129, Seedat, Soraya ORCID: https://orcid.org/0000-0002-5118-786X, Manková, Denisa ORCID: https://orcid.org/0000-0002-9705-9361, Guinart, Daniel ORCID: https://orcid.org/0000-0001-5078-6716, Vieta, Eduard ORCID: https://orcid.org/0000-0002-0548-0053, Millan, Mark J, De Leo, Diego ORCID: https://orcid.org/0000-0001-8255-6480, Berk, Michael ORCID: https://orcid.org/0000-0002-5554-6946, Fiedorowicz, Jess ORCID: https://orcid.org/0000-0003-2057-4071, Yang, Lin ORCID: https://orcid.org/0000-0002-1698-6666, Tiihonen, Jari ORCID: https://orcid.org/0000-0002-0400-6798, Aschauer, Harald ORCID: https://orcid.org/0000-0002-4449-372X, Schlögelhofer, Monika ORCID: https://orcid.org/0000-0003-0434-5527, Hamilton, Jane E ORCID: https://orcid.org/0000-0003-2109-1506, Solmi, Marco ORCID: https://orcid.org/0000-0003-4877-7233 and Correll, Christoph U ORCID: https://orcid.org/0000-0002-7254-5646 (2026) Well-being differences and changes in people with somatic and psychiatric disorders or multimorbidities: modelling COVID-19 as a global natural experiment of stress vulnerability. BMJ Mental Health, 29 (1):e302777. pp. 1-13. ISSN 2755-9734 (Online) (doi:10.1136/bmjment-2026-302777)