Items where Author is "Hartley, John A."

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3-Methylidene-Oxindoles agents antitumor-activity complexes design drugs inhibitors inverted CCAAT box kinase inhibitor metallocene nticancer agents nuclear factor Y organometallic chemistry palladium precatalysts pyrrolobenzodiazepine (PBD)-conjugate topoisomerase IIa

Number of items: 17.

3-Methylidene-Oxindoles

Spencer, John, Amin, Jahangir, Coxhead, Peter, McGeehan, John, Richards, Christopher J., Tizzard, Graham J., Coles, Simon J., Bingham, John P., Hartley, John A., Feng, Li, Meggers, Eric and Guille, Matthew (2011) Size does matter. Sterically demanding metallocene-substituted 3-methylidene-oxindoles exhibit poor kinase inhibitory action. Organometallics, 30 (11). pp. 3177-3181. ISSN 0276-7333 (Print), 1520-6041 (Online) (doi:10.1021/om200278j)

agents

Spencer, John, Rathnam, Rajendra P., Montukuri, Mahesh, Kotha, Arun K., Richardson, Simon C.W. ORCID: https://orcid.org/0000-0002-7927-0649, Hazrati, Ali, Hartley, John A., Male, Louise and Hursthouse, Michael B. (2009) Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity. Dalton Transactions (22). pp. 4299-4303. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:10.1039/b819061e)

antitumor-activity

Spencer, John, Rathnam, Rajendra P., Montukuri, Mahesh, Kotha, Arun K., Richardson, Simon C.W. ORCID: https://orcid.org/0000-0002-7927-0649, Hazrati, Ali, Hartley, John A., Male, Louise and Hursthouse, Michael B. (2009) Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity. Dalton Transactions (22). pp. 4299-4303. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:10.1039/b819061e)

complexes

Spencer, John, Rathnam, Rajendra P., Montukuri, Mahesh, Kotha, Arun K., Richardson, Simon C.W. ORCID: https://orcid.org/0000-0002-7927-0649, Hazrati, Ali, Hartley, John A., Male, Louise and Hursthouse, Michael B. (2009) Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity. Dalton Transactions (22). pp. 4299-4303. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:10.1039/b819061e)

design

Spencer, John, Rathnam, Rajendra P., Montukuri, Mahesh, Kotha, Arun K., Richardson, Simon C.W. ORCID: https://orcid.org/0000-0002-7927-0649, Hazrati, Ali, Hartley, John A., Male, Louise and Hursthouse, Michael B. (2009) Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity. Dalton Transactions (22). pp. 4299-4303. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:10.1039/b819061e)

drugs

Spencer, John, Rathnam, Rajendra P., Montukuri, Mahesh, Kotha, Arun K., Richardson, Simon C.W. ORCID: https://orcid.org/0000-0002-7927-0649, Hazrati, Ali, Hartley, John A., Male, Louise and Hursthouse, Michael B. (2009) Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity. Dalton Transactions (22). pp. 4299-4303. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:10.1039/b819061e)

inhibitors

Spencer, John, Rathnam, Rajendra P., Montukuri, Mahesh, Kotha, Arun K., Richardson, Simon C.W. ORCID: https://orcid.org/0000-0002-7927-0649, Hazrati, Ali, Hartley, John A., Male, Louise and Hursthouse, Michael B. (2009) Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity. Dalton Transactions (22). pp. 4299-4303. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:10.1039/b819061e)

inverted CCAAT box

Brucoli, Federico, Hawkins, Rachel M., James, Colin H., Wells, Geoff, Jenkins, Terrence C., Ellis, Tom, Hartley, John A., Howard, Philip W. and Thurston, David E. (2011) Novel C8-linked pyrrolobenzodiazepine (PBD)-heterocycle conjugates that recognize DNA sequences containing an inverted CCAAT box. Bioorganic & Medicinal Chemistry Letters, 21. pp. 3780-3783. ISSN 0960-894X (online) (doi:10.1016/j.bmcl.2011.04.054)

kinase inhibitor

Spencer, John, Amin, Jahangir, Coxhead, Peter, McGeehan, John, Richards, Christopher J., Tizzard, Graham J., Coles, Simon J., Bingham, John P., Hartley, John A., Feng, Li, Meggers, Eric and Guille, Matthew (2011) Size does matter. Sterically demanding metallocene-substituted 3-methylidene-oxindoles exhibit poor kinase inhibitory action. Organometallics, 30 (11). pp. 3177-3181. ISSN 0276-7333 (Print), 1520-6041 (Online) (doi:10.1021/om200278j)

metallocene

Spencer, John, Amin, Jahangir, Coxhead, Peter, McGeehan, John, Richards, Christopher J., Tizzard, Graham J., Coles, Simon J., Bingham, John P., Hartley, John A., Feng, Li, Meggers, Eric and Guille, Matthew (2011) Size does matter. Sterically demanding metallocene-substituted 3-methylidene-oxindoles exhibit poor kinase inhibitory action. Organometallics, 30 (11). pp. 3177-3181. ISSN 0276-7333 (Print), 1520-6041 (Online) (doi:10.1021/om200278j)

nticancer agents

Brucoli, Federico, Hawkins, Rachel M., James, Colin H., Wells, Geoff, Jenkins, Terrence C., Ellis, Tom, Hartley, John A., Howard, Philip W. and Thurston, David E. (2011) Novel C8-linked pyrrolobenzodiazepine (PBD)-heterocycle conjugates that recognize DNA sequences containing an inverted CCAAT box. Bioorganic & Medicinal Chemistry Letters, 21. pp. 3780-3783. ISSN 0960-894X (online) (doi:10.1016/j.bmcl.2011.04.054)

nuclear factor Y

Brucoli, Federico, Hawkins, Rachel M., James, Colin H., Wells, Geoff, Jenkins, Terrence C., Ellis, Tom, Hartley, John A., Howard, Philip W. and Thurston, David E. (2011) Novel C8-linked pyrrolobenzodiazepine (PBD)-heterocycle conjugates that recognize DNA sequences containing an inverted CCAAT box. Bioorganic & Medicinal Chemistry Letters, 21. pp. 3780-3783. ISSN 0960-894X (online) (doi:10.1016/j.bmcl.2011.04.054)

organometallic chemistry

Spencer, John, Rathnam, Rajendra P., Montukuri, Mahesh, Kotha, Arun K., Richardson, Simon C.W. ORCID: https://orcid.org/0000-0002-7927-0649, Hazrati, Ali, Hartley, John A., Male, Louise and Hursthouse, Michael B. (2009) Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity. Dalton Transactions (22). pp. 4299-4303. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:10.1039/b819061e)

palladium

Spencer, John, Rathnam, Rajendra P., Montukuri, Mahesh, Kotha, Arun K., Richardson, Simon C.W. ORCID: https://orcid.org/0000-0002-7927-0649, Hazrati, Ali, Hartley, John A., Male, Louise and Hursthouse, Michael B. (2009) Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity. Dalton Transactions (22). pp. 4299-4303. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:10.1039/b819061e)

precatalysts

Spencer, John, Rathnam, Rajendra P., Montukuri, Mahesh, Kotha, Arun K., Richardson, Simon C.W. ORCID: https://orcid.org/0000-0002-7927-0649, Hazrati, Ali, Hartley, John A., Male, Louise and Hursthouse, Michael B. (2009) Synthesis of a 1,4-benzodiazepine containing palladacycle with in vitro anticancer and cathepsin B activity. Dalton Transactions (22). pp. 4299-4303. ISSN 1477-9226 (Print), 1477-9234 (Online) (doi:10.1039/b819061e)

pyrrolobenzodiazepine (PBD)-conjugate

Brucoli, Federico, Hawkins, Rachel M., James, Colin H., Wells, Geoff, Jenkins, Terrence C., Ellis, Tom, Hartley, John A., Howard, Philip W. and Thurston, David E. (2011) Novel C8-linked pyrrolobenzodiazepine (PBD)-heterocycle conjugates that recognize DNA sequences containing an inverted CCAAT box. Bioorganic & Medicinal Chemistry Letters, 21. pp. 3780-3783. ISSN 0960-894X (online) (doi:10.1016/j.bmcl.2011.04.054)

topoisomerase IIa

Brucoli, Federico, Hawkins, Rachel M., James, Colin H., Wells, Geoff, Jenkins, Terrence C., Ellis, Tom, Hartley, John A., Howard, Philip W. and Thurston, David E. (2011) Novel C8-linked pyrrolobenzodiazepine (PBD)-heterocycle conjugates that recognize DNA sequences containing an inverted CCAAT box. Bioorganic & Medicinal Chemistry Letters, 21. pp. 3780-3783. ISSN 0960-894X (online) (doi:10.1016/j.bmcl.2011.04.054)

This list was generated on Sun Dec 22 13:41:27 2024 UTC.