Items where Author is "Harbige, L.S."
14-prostaglandin J2
Xiang, M., Pinto, E., Rahman, M.A., Leach, M. ORCID: https://orcid.org/0000-0002-9859-1325 and Harbige, L.S. (2010) Decreased monocyte chemoattractant protein 1 and relationship with 15-deoxy-delta 12,14- prostaglandin J2 in gamma-linolenic acid supplemented healthy subjects. Proceedings of the Nutrition Society, 69 (OCE3). E325-E325. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S002966511000114X)
15-deoxy-12
Xiang, M., Pinto, E., Rahman, M.A., Leach, M. ORCID: https://orcid.org/0000-0002-9859-1325 and Harbige, L.S. (2010) Decreased monocyte chemoattractant protein 1 and relationship with 15-deoxy-delta 12,14- prostaglandin J2 in gamma-linolenic acid supplemented healthy subjects. Proceedings of the Nutrition Society, 69 (OCE3). E325-E325. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S002966511000114X)
adipokine
Xiao, H., Xiang, M., Harbige, L.S. and Ai, H. (2010) Relation between visfatin as a novel adipokine and AMP-activated protein kinase in obesity. Proceedings of the Nutrition Society, 69 (OCE3). E324-E324. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665110001138)
AMP-activated protein kinase
Xiao, H., Xiang, M., Harbige, L.S. and Ai, H. (2010) Relation between visfatin as a novel adipokine and AMP-activated protein kinase in obesity. Proceedings of the Nutrition Society, 69 (OCE3). E324-E324. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665110001138)
BGC20-884
Harbige, L.S., Pinto, E., Xiang, M., Leach, M. ORCID: https://orcid.org/0000-0002-9859-1325 and Sharief, M. K. (2008) PUFA in the pathogenesis and treatment of patients with multiple sclerosis. Proceedings of the Nutrition Society, 67 (OCE1). E21. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665108006307)
blood
Xiang, M., Al-Hassi, H.O., Harbige, L.S. and Knight, S.C. (2011) Gene expression of delta-6-desaturase in peripheral blood mononuclear cells, β7+ and β7 lymphocytes in healthy controls and patients with Crohn's disease. Proceedings of the Nutrition Society, 70 (OCE2). E44-E44. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665111000759)
blood mononuclear cells
Pinto, E., Xiang, M., Leach, M. ORCID: https://orcid.org/0000-0002-9859-1325 and Harbige, L.S. (2006) Effects of ω-6 fatty acid supplementation on chemokine production by peripheral blood mononuclear cells from healthy volunteers. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)
Pinto, E. and Harbige, L.S. (2006) Effects of ω-6 fatty acids on human monocyte and T-cell adhesion molecule expression. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)
borage
Xiang, M., Pinto, E., Rahman, M.A., Leach, M. ORCID: https://orcid.org/0000-0002-9859-1325 and Harbige, L.S. (2008) Borage (Borago officinalis) oil supplementation in relation to monocyte chemoattractant protein 1 expression in healthy subjects. Proceedings of the Nutrition Society, 67 (OCE1). E44-E44. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665108006538)
Harbige, L.S., Pinto, E., Xiang, M., Leach, M. ORCID: https://orcid.org/0000-0002-9859-1325 and Sharief, M. K. (2008) PUFA in the pathogenesis and treatment of patients with multiple sclerosis. Proceedings of the Nutrition Society, 67 (OCE1). E21. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665108006307)
case studies
Pinto, E., Xiang, M., Leach, M. ORCID: https://orcid.org/0000-0002-9859-1325 and Harbige, L.S. (2006) Effects of ω-6 fatty acid supplementation on chemokine production by peripheral blood mononuclear cells from healthy volunteers. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)
Pinto, E. and Harbige, L.S. (2006) Effects of ω-6 fatty acids on human monocyte and T-cell adhesion molecule expression. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)
chemokine
Pinto, E., Xiang, M., Leach, M. ORCID: https://orcid.org/0000-0002-9859-1325 and Harbige, L.S. (2006) Effects of ω-6 fatty acid supplementation on chemokine production by peripheral blood mononuclear cells from healthy volunteers. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)
Pinto, E. and Harbige, L.S. (2006) Effects of ω-6 fatty acids on human monocyte and T-cell adhesion molecule expression. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)
child growth
Xiang, M., Harbige, L.S. and Zetterström, R. (2006) Relationship between zinc and ω-6 polyunsaturated fatty acids in breast milk and infant growth. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)
chronic inflammatory disease
Xiang, M., Pinto, E., Rahman, M.A., Leach, M. ORCID: https://orcid.org/0000-0002-9859-1325 and Harbige, L.S. (2008) Borage (Borago officinalis) oil supplementation in relation to monocyte chemoattractant protein 1 expression in healthy subjects. Proceedings of the Nutrition Society, 67 (OCE1). E44-E44. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665108006538)
copper
Harbige, L.S., Pinto, E., Xiang, M. and Shareif, M.K. (2011) Circulating plasma cytokines, zinc, copper, vitamins A and E in multiple sclerosis patients and healthy controls. Proceedings of the Nutrition Society, 70 (OCE2). E36-E36. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S002966511100067X)
creatine
Li, X., Xiang, M., Harbige, L.S. and Ai, H. (2008) Effect of cessation of creatine supplementation on endogenous creatine synthesis. Proceedings of the Nutrition Society, 67 (OCE1). E49. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665108006587)
Xiang, M., Harbige, L.S., Li, X., Li, B. and Ai, H. (2008) Time-course study of high-dose creatine supplementation for endogenous creatine synthesis. Proceedings of the Nutrition Society, 67 (OCE1). E80. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665108006897)
Crohn's disease
Xiang, M., Al-Hassi, H.O., Harbige, L.S. and Knight, S.C. (2011) Gene expression of delta-6-desaturase in peripheral blood mononuclear cells, β7+ and β7 lymphocytes in healthy controls and patients with Crohn's disease. Proceedings of the Nutrition Society, 70 (OCE2). E44-E44. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665111000759)
delta-5
Xiang, Mingyan, Rahman, Mohammed, Ai, H., Li, X and Harbige, L.S. (2006) Relationship between dietary fat intake and gene expression of delta-6 and delta-5 desaturases. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)
delta-6
Xiang, Mingyan, Rahman, Mohammed, Ai, H., Li, X and Harbige, L.S. (2006) Relationship between dietary fat intake and gene expression of delta-6 and delta-5 desaturases. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)
delta-6-desaturase
Xiang, M., Al-Hassi, H.O., Harbige, L.S. and Knight, S.C. (2011) Gene expression of delta-6-desaturase in peripheral blood mononuclear cells, β7+ and β7 lymphocytes in healthy controls and patients with Crohn's disease. Proceedings of the Nutrition Society, 70 (OCE2). E44-E44. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665111000759)
desaturases
Xiang, Mingyan, Rahman, Mohammed, Ai, H., Li, X and Harbige, L.S. (2006) Relationship between dietary fat intake and gene expression of delta-6 and delta-5 desaturases. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)
dietary fat intake
Xiang, Mingyan, Rahman, Mohammed, Ai, H., Li, X and Harbige, L.S. (2006) Relationship between dietary fat intake and gene expression of delta-6 and delta-5 desaturases. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)
effect of exercise
Xiang, M., Liu, W., Harbige, L.S. and Ai, H. (2011) Ghrelin expression and effect of exercise in obesity. Proceedings of the Nutrition Society, 70 (OCE2). E45-E45. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665111000760)
endogenous creatine synthesis
Li, X., Xiang, M., Harbige, L.S., Meng, P.X. and Ai, H. (2010) Study of low-dose creatine supplementation for endogenous creatine synthesis during heavy-load exercise. Proceedings of the Nutrition Society, 69 (OCE3). E322-E322. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665110001114)
exercise
Li, X., Xiang, M., Harbige, L.S., Meng, P.X. and Ai, H. (2010) Study of low-dose creatine supplementation for endogenous creatine synthesis during heavy-load exercise. Proceedings of the Nutrition Society, 69 (OCE3). E322-E322. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665110001114)
fatty acids
Pinto, E., Xiang, M., Leach, M. ORCID: https://orcid.org/0000-0002-9859-1325 and Harbige, L.S. (2006) Effects of ω-6 fatty acid supplementation on chemokine production by peripheral blood mononuclear cells from healthy volunteers. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)
Pinto, E. and Harbige, L.S. (2006) Effects of ω-6 fatty acids on human monocyte and T-cell adhesion molecule expression. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)
gamma-linolenic acid
Xiang, M., Pinto, E., Rahman, M.A., Leach, M. ORCID: https://orcid.org/0000-0002-9859-1325 and Harbige, L.S. (2010) Decreased monocyte chemoattractant protein 1 and relationship with 15-deoxy-delta 12,14- prostaglandin J2 in gamma-linolenic acid supplemented healthy subjects. Proceedings of the Nutrition Society, 69 (OCE3). E325-E325. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S002966511000114X)
gamma-linolneic acid
Xiang, M., Pinto, E., Rahman, M.A., Leach, M. ORCID: https://orcid.org/0000-0002-9859-1325 and Harbige, L.S. (2008) Borage (Borago officinalis) oil supplementation in relation to monocyte chemoattractant protein 1 expression in healthy subjects. Proceedings of the Nutrition Society, 67 (OCE1). E44-E44. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665108006538)
gene expression
Xiang, M., Al-Hassi, H.O., Harbige, L.S. and Knight, S.C. (2011) Gene expression of delta-6-desaturase in peripheral blood mononuclear cells, β7+ and β7 lymphocytes in healthy controls and patients with Crohn's disease. Proceedings of the Nutrition Society, 70 (OCE2). E44-E44. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665111000759)
Xiang, Mingyan, Rahman, Mohammed, Ai, H., Li, X and Harbige, L.S. (2006) Relationship between dietary fat intake and gene expression of delta-6 and delta-5 desaturases. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)
Ghrelin expression
Xiang, M., Liu, W., Harbige, L.S. and Ai, H. (2011) Ghrelin expression and effect of exercise in obesity. Proceedings of the Nutrition Society, 70 (OCE2). E45-E45. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665111000760)
GLA
Xiang, M., Pinto, E., Rahman, M.A., Leach, M. ORCID: https://orcid.org/0000-0002-9859-1325 and Harbige, L.S. (2008) Borage (Borago officinalis) oil supplementation in relation to monocyte chemoattractant protein 1 expression in healthy subjects. Proceedings of the Nutrition Society, 67 (OCE1). E44-E44. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665108006538)
leptin
Chaidas, M. and Harbige, L.S. (2011) Relationship between circulating leptin and TNFα in obese and non-obese human subjects in the UK. Proceedings of the Nutrition Society, 70 (OCE2). E30-E30. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665111000619)
low-dose creatine supplementation
Li, X., Xiang, M., Harbige, L.S., Meng, P.X. and Ai, H. (2010) Study of low-dose creatine supplementation for endogenous creatine synthesis during heavy-load exercise. Proceedings of the Nutrition Society, 69 (OCE3). E322-E322. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665110001114)
maternal milk
Xiang, M., Harbige, L.S. and Zetterström, R. (2006) Relationship between zinc and ω-6 polyunsaturated fatty acids in breast milk and infant growth. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)
monocyte chemoattractant protein 1
Xiang, M., Pinto, E., Rahman, M.A., Leach, M. ORCID: https://orcid.org/0000-0002-9859-1325 and Harbige, L.S. (2010) Decreased monocyte chemoattractant protein 1 and relationship with 15-deoxy-delta 12,14- prostaglandin J2 in gamma-linolenic acid supplemented healthy subjects. Proceedings of the Nutrition Society, 69 (OCE3). E325-E325. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S002966511000114X)
Xiang, M., Pinto, E., Rahman, M.A., Leach, M. ORCID: https://orcid.org/0000-0002-9859-1325 and Harbige, L.S. (2008) Borage (Borago officinalis) oil supplementation in relation to monocyte chemoattractant protein 1 expression in healthy subjects. Proceedings of the Nutrition Society, 67 (OCE1). E44-E44. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665108006538)
MS
Harbige, L.S., Pinto, E., Xiang, M., Leach, M. ORCID: https://orcid.org/0000-0002-9859-1325 and Sharief, M. K. (2008) PUFA in the pathogenesis and treatment of patients with multiple sclerosis. Proceedings of the Nutrition Society, 67 (OCE1). E21. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665108006307)
multiple sclerosis
Harbige, L.S., Pinto, E., Xiang, M., Leach, M. ORCID: https://orcid.org/0000-0002-9859-1325 and Sharief, M. K. (2008) PUFA in the pathogenesis and treatment of patients with multiple sclerosis. Proceedings of the Nutrition Society, 67 (OCE1). E21. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665108006307)
multiple sclerosis patients
Harbige, L.S., Pinto, E., Xiang, M. and Shareif, M.K. (2011) Circulating plasma cytokines, zinc, copper, vitamins A and E in multiple sclerosis patients and healthy controls. Proceedings of the Nutrition Society, 70 (OCE2). E36-E36. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S002966511100067X)
non-obese
Chaidas, M. and Harbige, L.S. (2011) Relationship between circulating leptin and TNFα in obese and non-obese human subjects in the UK. Proceedings of the Nutrition Society, 70 (OCE2). E30-E30. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665111000619)
obese
Chaidas, M. and Harbige, L.S. (2011) Relationship between circulating leptin and TNFα in obese and non-obese human subjects in the UK. Proceedings of the Nutrition Society, 70 (OCE2). E30-E30. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665111000619)
obesity
Xiang, M., Liu, W., Harbige, L.S. and Ai, H. (2011) Ghrelin expression and effect of exercise in obesity. Proceedings of the Nutrition Society, 70 (OCE2). E45-E45. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665111000760)
Xiao, H., Xiang, M., Harbige, L.S. and Ai, H. (2011) Visfatin as a novel adipokine in relation to AMP-activated protein kinase in obesity and weight loss. Proceedings of the Nutrition Society, 70 (OCE2). E46-E46. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665111000772)
Xiao, H., Xiang, M., Harbige, L.S. and Ai, H. (2010) Relation between visfatin as a novel adipokine and AMP-activated protein kinase in obesity. Proceedings of the Nutrition Society, 69 (OCE3). E324-E324. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665110001138)
plasma cytokines
Harbige, L.S., Pinto, E., Xiang, M. and Shareif, M.K. (2011) Circulating plasma cytokines, zinc, copper, vitamins A and E in multiple sclerosis patients and healthy controls. Proceedings of the Nutrition Society, 70 (OCE2). E36-E36. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S002966511100067X)
TNFα
Chaidas, M. and Harbige, L.S. (2011) Relationship between circulating leptin and TNFα in obese and non-obese human subjects in the UK. Proceedings of the Nutrition Society, 70 (OCE2). E30-E30. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665111000619)
United Kingdom
Chaidas, M. and Harbige, L.S. (2011) Relationship between circulating leptin and TNFα in obese and non-obese human subjects in the UK. Proceedings of the Nutrition Society, 70 (OCE2). E30-E30. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665111000619)
Visfatin
Xiao, H., Xiang, M., Harbige, L.S. and Ai, H. (2011) Visfatin as a novel adipokine in relation to AMP-activated protein kinase in obesity and weight loss. Proceedings of the Nutrition Society, 70 (OCE2). E46-E46. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665111000772)
Xiao, H., Xiang, M., Harbige, L.S. and Ai, H. (2010) Relation between visfatin as a novel adipokine and AMP-activated protein kinase in obesity. Proceedings of the Nutrition Society, 69 (OCE3). E324-E324. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665110001138)
vitamin A
Harbige, L.S., Pinto, E., Xiang, M. and Shareif, M.K. (2011) Circulating plasma cytokines, zinc, copper, vitamins A and E in multiple sclerosis patients and healthy controls. Proceedings of the Nutrition Society, 70 (OCE2). E36-E36. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S002966511100067X)
vitamin E
Harbige, L.S., Pinto, E., Xiang, M. and Shareif, M.K. (2011) Circulating plasma cytokines, zinc, copper, vitamins A and E in multiple sclerosis patients and healthy controls. Proceedings of the Nutrition Society, 70 (OCE2). E36-E36. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S002966511100067X)
w-6 fatty acid
Pinto, E., Xiang, M., Leach, M. ORCID: https://orcid.org/0000-0002-9859-1325 and Harbige, L.S. (2006) Effects of ω-6 fatty acid supplementation on chemokine production by peripheral blood mononuclear cells from healthy volunteers. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)
Pinto, E. and Harbige, L.S. (2006) Effects of ω-6 fatty acids on human monocyte and T-cell adhesion molecule expression. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)
w-6 polyunsaturated fatty acids
Xiang, M., Harbige, L.S. and Zetterström, R. (2006) Relationship between zinc and ω-6 polyunsaturated fatty acids in breast milk and infant growth. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)
weight loss
Xiao, H., Xiang, M., Harbige, L.S. and Ai, H. (2011) Visfatin as a novel adipokine in relation to AMP-activated protein kinase in obesity and weight loss. Proceedings of the Nutrition Society, 70 (OCE2). E46-E46. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S0029665111000772)
zinc
Harbige, L.S., Pinto, E., Xiang, M. and Shareif, M.K. (2011) Circulating plasma cytokines, zinc, copper, vitamins A and E in multiple sclerosis patients and healthy controls. Proceedings of the Nutrition Society, 70 (OCE2). E36-E36. ISSN 0029-6651 (Print), 1475-2719 (Online) (doi:10.1017/S002966511100067X)
Xiang, M., Harbige, L.S. and Zetterström, R. (2006) Relationship between zinc and ω-6 polyunsaturated fatty acids in breast milk and infant growth. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)