adriamycin

Greco, Olga, Powell, Tanya M., Marples, Brian, Joiner, Michael C. and Scott, Simon D. (2005) Gene therapy vectors containing CArG elements from the Egr1 gene are activated by neutron irradiation, cisplatin and doxorubicin. Cancer Gene Therapy, 12 (7). pp. 655-662. ISSN 0929-1903 (Print), 1476-5500 (Online) (doi:10.1038/sj.cgt.7700834)

bioreductive drugs

Greco, Olga and Scott, Simon (2007) Tumor hypoxia and targeted gene therapy. International Review of Cytology, 257. pp. 181-212. ISSN 0074-7696 (doi:10.1016/S0074-7696(07)57005-1)

breast cancer xenografts

Lipnik, Karoline, Greco, Olga, Scott, Simon, Knapp, Elzbieta, Mayrhofer, Elisabeth, Rosenfellner, Doris, Günzburg, Walter H., Salmons, Brian and Hohenadl, Christine (2006) Hypoxia- and radiation-inducible, breast cell-specific targeting of retroviral vectors. Virology, 349 (1). pp. 121-133. ISSN 0042-6822 (doi:10.1016/j.virol.2005.12.038)

breast cell-specific expression targeting

Lipnik, Karoline, Greco, Olga, Scott, Simon, Knapp, Elzbieta, Mayrhofer, Elisabeth, Rosenfellner, Doris, Günzburg, Walter H., Salmons, Brian and Hohenadl, Christine (2006) Hypoxia- and radiation-inducible, breast cell-specific targeting of retroviral vectors. Virology, 349 (1). pp. 121-133. ISSN 0042-6822 (doi:10.1016/j.virol.2005.12.038)

cancer

Greco, Olga, Marples, Brian, Joiner, Michael C. and Scott, Simon D. (2003) How to overcome (and exploit) tumor hypoxia for targeted gene therapy. Journal of Cellular Physiology, 197 (3). pp. 312-325. ISSN 0021-9541 (Print), 1097-4652 (Online) (doi:10.1002/jcp.10374)

CArG element

Lipnik, Karoline, Greco, Olga, Scott, Simon, Knapp, Elzbieta, Mayrhofer, Elisabeth, Rosenfellner, Doris, Günzburg, Walter H., Salmons, Brian and Hohenadl, Christine (2006) Hypoxia- and radiation-inducible, breast cell-specific targeting of retroviral vectors. Virology, 349 (1). pp. 121-133. ISSN 0042-6822 (doi:10.1016/j.virol.2005.12.038)

CArG elements

Greco, Olga and Scott, Simon (2007) Tumor hypoxia and targeted gene therapy. International Review of Cytology, 257. pp. 181-212. ISSN 0074-7696 (doi:10.1016/S0074-7696(07)57005-1)

chemotherapy

Greco, Olga and Scott, Simon (2007) Tumor hypoxia and targeted gene therapy. International Review of Cytology, 257. pp. 181-212. ISSN 0074-7696 (doi:10.1016/S0074-7696(07)57005-1)

Cre/lox recombination

Scott, Simon D. and Greco, Olga (2004) Radiation and hypoxia inducible gene therapy systems. Cancer and Metastasis Reviews, 23 (3-4). pp. 269-276. ISSN 0167-7659 (Print), 1573-7233 (Online) (doi:10.1023/B:CANC.0000031766.58614.f1)

Cre/loxP

Greco, Olga and Scott, Simon (2007) Tumor hypoxia and targeted gene therapy. International Review of Cytology, 257. pp. 181-212. ISSN 0074-7696 (doi:10.1016/S0074-7696(07)57005-1)

enhancer

Chadderton, Naomi, Cowen, Rachel L., Sheppard, Freda C.D, Robinson, Suzanne, Greco, Olga, Scott, Simon D., Stratford, Ian J., Patterson, Adam V. and Williams, Kaye J. (2005) Dual responsive promoters to target therapeutic gene expression to radiation-resistant hypoxic tumour cells. International Journal of Radiation Oncology*Biology*Physics, 62 (1). pp. 213-222. ISSN 0360-3016 (doi:10.1016/j.ijrobp.2005.01.031)

gene therapy

Greco, Olga, Marples, Brian, Joiner, Michael C. and Scott, Simon D. (2003) How to overcome (and exploit) tumor hypoxia for targeted gene therapy. Journal of Cellular Physiology, 197 (3). pp. 312-325. ISSN 0021-9541 (Print), 1097-4652 (Online) (doi:10.1002/jcp.10374)

genetic radiotherapy

Chadderton, Naomi, Cowen, Rachel L., Sheppard, Freda C.D, Robinson, Suzanne, Greco, Olga, Scott, Simon D., Stratford, Ian J., Patterson, Adam V. and Williams, Kaye J. (2005) Dual responsive promoters to target therapeutic gene expression to radiation-resistant hypoxic tumour cells. International Journal of Radiation Oncology*Biology*Physics, 62 (1). pp. 213-222. ISSN 0360-3016 (doi:10.1016/j.ijrobp.2005.01.031)

GFP

Greco, Olga, Powell, Tanya M., Marples, Brian, Joiner, Michael C. and Scott, Simon D. (2005) Gene therapy vectors containing CArG elements from the Egr1 gene are activated by neutron irradiation, cisplatin and doxorubicin. Cancer Gene Therapy, 12 (7). pp. 655-662. ISSN 0929-1903 (Print), 1476-5500 (Online) (doi:10.1038/sj.cgt.7700834)

HIF

Greco, Olga and Scott, Simon (2007) Tumor hypoxia and targeted gene therapy. International Review of Cytology, 257. pp. 181-212. ISSN 0074-7696 (doi:10.1016/S0074-7696(07)57005-1)

Chadderton, Naomi, Cowen, Rachel L., Sheppard, Freda C.D, Robinson, Suzanne, Greco, Olga, Scott, Simon D., Stratford, Ian J., Patterson, Adam V. and Williams, Kaye J. (2005) Dual responsive promoters to target therapeutic gene expression to radiation-resistant hypoxic tumour cells. International Journal of Radiation Oncology*Biology*Physics, 62 (1). pp. 213-222. ISSN 0360-3016 (doi:10.1016/j.ijrobp.2005.01.031)

HRE

Greco, Olga and Scott, Simon (2007) Tumor hypoxia and targeted gene therapy. International Review of Cytology, 257. pp. 181-212. ISSN 0074-7696 (doi:10.1016/S0074-7696(07)57005-1)

HSVtk/GCV

Greco, Olga, Powell, Tanya M., Marples, Brian, Joiner, Michael C. and Scott, Simon D. (2005) Gene therapy vectors containing CArG elements from the Egr1 gene are activated by neutron irradiation, cisplatin and doxorubicin. Cancer Gene Therapy, 12 (7). pp. 655-662. ISSN 0929-1903 (Print), 1476-5500 (Online) (doi:10.1038/sj.cgt.7700834)

hypoxia

Chadderton, Naomi, Cowen, Rachel L., Sheppard, Freda C.D, Robinson, Suzanne, Greco, Olga, Scott, Simon D., Stratford, Ian J., Patterson, Adam V. and Williams, Kaye J. (2005) Dual responsive promoters to target therapeutic gene expression to radiation-resistant hypoxic tumour cells. International Journal of Radiation Oncology*Biology*Physics, 62 (1). pp. 213-222. ISSN 0360-3016 (doi:10.1016/j.ijrobp.2005.01.031)

Scott, Simon D. and Greco, Olga (2004) Radiation and hypoxia inducible gene therapy systems. Cancer and Metastasis Reviews, 23 (3-4). pp. 269-276. ISSN 0167-7659 (Print), 1573-7233 (Online) (doi:10.1023/B:CANC.0000031766.58614.f1)

Greco, Olga, Marples, Brian, Joiner, Michael C. and Scott, Simon D. (2003) How to overcome (and exploit) tumor hypoxia for targeted gene therapy. Journal of Cellular Physiology, 197 (3). pp. 312-325. ISSN 0021-9541 (Print), 1097-4652 (Online) (doi:10.1002/jcp.10374)

hypoxia responsive element

Lipnik, Karoline, Greco, Olga, Scott, Simon, Knapp, Elzbieta, Mayrhofer, Elisabeth, Rosenfellner, Doris, Günzburg, Walter H., Salmons, Brian and Hohenadl, Christine (2006) Hypoxia- and radiation-inducible, breast cell-specific targeting of retroviral vectors. Virology, 349 (1). pp. 121-133. ISSN 0042-6822 (doi:10.1016/j.virol.2005.12.038)

mouse model

Lipnik, Karoline, Greco, Olga, Scott, Simon, Knapp, Elzbieta, Mayrhofer, Elisabeth, Rosenfellner, Doris, Günzburg, Walter H., Salmons, Brian and Hohenadl, Christine (2006) Hypoxia- and radiation-inducible, breast cell-specific targeting of retroviral vectors. Virology, 349 (1). pp. 121-133. ISSN 0042-6822 (doi:10.1016/j.virol.2005.12.038)

oncology

Greco, Olga, Marples, Brian, Joiner, Michael C. and Scott, Simon D. (2003) How to overcome (and exploit) tumor hypoxia for targeted gene therapy. Journal of Cellular Physiology, 197 (3). pp. 312-325. ISSN 0021-9541 (Print), 1097-4652 (Online) (doi:10.1002/jcp.10374)

promoter conversion

Lipnik, Karoline, Greco, Olga, Scott, Simon, Knapp, Elzbieta, Mayrhofer, Elisabeth, Rosenfellner, Doris, Günzburg, Walter H., Salmons, Brian and Hohenadl, Christine (2006) Hypoxia- and radiation-inducible, breast cell-specific targeting of retroviral vectors. Virology, 349 (1). pp. 121-133. ISSN 0042-6822 (doi:10.1016/j.virol.2005.12.038)

promoters

Scott, Simon D. and Greco, Olga (2004) Radiation and hypoxia inducible gene therapy systems. Cancer and Metastasis Reviews, 23 (3-4). pp. 269-276. ISSN 0167-7659 (Print), 1573-7233 (Online) (doi:10.1023/B:CANC.0000031766.58614.f1)

radiation

Greco, Olga and Scott, Simon (2007) Tumor hypoxia and targeted gene therapy. International Review of Cytology, 257. pp. 181-212. ISSN 0074-7696 (doi:10.1016/S0074-7696(07)57005-1)

Chadderton, Naomi, Cowen, Rachel L., Sheppard, Freda C.D, Robinson, Suzanne, Greco, Olga, Scott, Simon D., Stratford, Ian J., Patterson, Adam V. and Williams, Kaye J. (2005) Dual responsive promoters to target therapeutic gene expression to radiation-resistant hypoxic tumour cells. International Journal of Radiation Oncology*Biology*Physics, 62 (1). pp. 213-222. ISSN 0360-3016 (doi:10.1016/j.ijrobp.2005.01.031)

Greco, Olga, Powell, Tanya M., Marples, Brian, Joiner, Michael C. and Scott, Simon D. (2005) Gene therapy vectors containing CArG elements from the Egr1 gene are activated by neutron irradiation, cisplatin and doxorubicin. Cancer Gene Therapy, 12 (7). pp. 655-662. ISSN 0929-1903 (Print), 1476-5500 (Online) (doi:10.1038/sj.cgt.7700834)

Scott, Simon D. and Greco, Olga (2004) Radiation and hypoxia inducible gene therapy systems. Cancer and Metastasis Reviews, 23 (3-4). pp. 269-276. ISSN 0167-7659 (Print), 1573-7233 (Online) (doi:10.1023/B:CANC.0000031766.58614.f1)

retroviral vector

Lipnik, Karoline, Greco, Olga, Scott, Simon, Knapp, Elzbieta, Mayrhofer, Elisabeth, Rosenfellner, Doris, Günzburg, Walter H., Salmons, Brian and Hohenadl, Christine (2006) Hypoxia- and radiation-inducible, breast cell-specific targeting of retroviral vectors. Virology, 349 (1). pp. 121-133. ISSN 0042-6822 (doi:10.1016/j.virol.2005.12.038)

suicide gene

Scott, Simon D. and Greco, Olga (2004) Radiation and hypoxia inducible gene therapy systems. Cancer and Metastasis Reviews, 23 (3-4). pp. 269-276. ISSN 0167-7659 (Print), 1573-7233 (Online) (doi:10.1023/B:CANC.0000031766.58614.f1)

suicide gene therapy

Greco, Olga and Scott, Simon (2007) Tumor hypoxia and targeted gene therapy. International Review of Cytology, 257. pp. 181-212. ISSN 0074-7696 (doi:10.1016/S0074-7696(07)57005-1)

targeting

Scott, Simon D. and Greco, Olga (2004) Radiation and hypoxia inducible gene therapy systems. Cancer and Metastasis Reviews, 23 (3-4). pp. 269-276. ISSN 0167-7659 (Print), 1573-7233 (Online) (doi:10.1023/B:CANC.0000031766.58614.f1)

tumor

Greco, Olga, Marples, Brian, Joiner, Michael C. and Scott, Simon D. (2003) How to overcome (and exploit) tumor hypoxia for targeted gene therapy. Journal of Cellular Physiology, 197 (3). pp. 312-325. ISSN 0021-9541 (Print), 1097-4652 (Online) (doi:10.1002/jcp.10374)