Acetylcholinesterase

Roselli, Mariagrazia, Cavalluzzi, Maria Maddalena, Bruno, Claudio, Lovece, Angelo, Carocci, Alessia, Franchini, Carlo, Habtemariam, Solomon and Lentini, Giovanni (2016) Synthesis and evaluation of berberine derivatives and analogues as potential anti-acetylcholinesterase and antioxidant agents. Phytochemistry Letters, 18. pp. 150-156. ISSN 1874-3900 (Print), 1876-7486 (Online) (doi:10.1016/j.phytol.2016.10.005)

Alzheimer’s disease

Roselli, Mariagrazia, Cavalluzzi, Maria Maddalena, Bruno, Claudio, Lovece, Angelo, Carocci, Alessia, Franchini, Carlo, Habtemariam, Solomon and Lentini, Giovanni (2016) Synthesis and evaluation of berberine derivatives and analogues as potential anti-acetylcholinesterase and antioxidant agents. Phytochemistry Letters, 18. pp. 150-156. ISSN 1874-3900 (Print), 1876-7486 (Online) (doi:10.1016/j.phytol.2016.10.005)

Antiarrhythmics

Roselli, Mariagrazia, Carocci, Alessia, Budriesi, Roberta, Micucci, Matteo, Toma, Maddalena, Di Cesare Mannelli, Lorenzo, Lovece, Angelo, Catalano, Alessia, Cavalluzzi, Maria Maddalena, Bruno, Claudio, De Palma, Annalisa, Contino, Marialessandra, Perrone, Maria Grazia, Colabufo, Nicola Antonio, Chiarini, Alberto, Franchini, Carlo, Ghelardini, Carla, Habtemariam, Solomon and Lentini, Giovanni (2016) Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues. European Journal of Medicinal Chemistry, 121. pp. 300-307. ISSN 0223-5234 (doi:10.1016/j.ejmech.2016.05.046)

Antioxidants

Roselli, Mariagrazia, Cavalluzzi, Maria Maddalena, Bruno, Claudio, Lovece, Angelo, Carocci, Alessia, Franchini, Carlo, Habtemariam, Solomon and Lentini, Giovanni (2016) Synthesis and evaluation of berberine derivatives and analogues as potential anti-acetylcholinesterase and antioxidant agents. Phytochemistry Letters, 18. pp. 150-156. ISSN 1874-3900 (Print), 1876-7486 (Online) (doi:10.1016/j.phytol.2016.10.005)

azetidine

Degennaro, Leonardo, Zenzola, Marina, Laurino, Annunziatina, Cavalluzzi, Maria Maddalena, Franchini, Carlo, Habtemariam, Solomon, Matucci, Rosanna, Luisi, Renzo and Lentini, Giovanni (2017) 2-Arylazetidines as ligands for nicotinic acetylcholine receptors. Chemistry of Heterocyclic Compounds, 53 (3). pp. 329-334. ISSN 0009-3122 (Print), 1573-8353 (Online) (doi:10.1007/s10593-017-2061-5)

Berberine

Roselli, Mariagrazia, Cavalluzzi, Maria Maddalena, Bruno, Claudio, Lovece, Angelo, Carocci, Alessia, Franchini, Carlo, Habtemariam, Solomon and Lentini, Giovanni (2016) Synthesis and evaluation of berberine derivatives and analogues as potential anti-acetylcholinesterase and antioxidant agents. Phytochemistry Letters, 18. pp. 150-156. ISSN 1874-3900 (Print), 1876-7486 (Online) (doi:10.1016/j.phytol.2016.10.005)

Inotropism

Roselli, Mariagrazia, Carocci, Alessia, Budriesi, Roberta, Micucci, Matteo, Toma, Maddalena, Di Cesare Mannelli, Lorenzo, Lovece, Angelo, Catalano, Alessia, Cavalluzzi, Maria Maddalena, Bruno, Claudio, De Palma, Annalisa, Contino, Marialessandra, Perrone, Maria Grazia, Colabufo, Nicola Antonio, Chiarini, Alberto, Franchini, Carlo, Ghelardini, Carla, Habtemariam, Solomon and Lentini, Giovanni (2016) Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues. European Journal of Medicinal Chemistry, 121. pp. 300-307. ISSN 0223-5234 (doi:10.1016/j.ejmech.2016.05.046)

ligand efficiency metrics

Degennaro, Leonardo, Zenzola, Marina, Laurino, Annunziatina, Cavalluzzi, Maria Maddalena, Franchini, Carlo, Habtemariam, Solomon, Matucci, Rosanna, Luisi, Renzo and Lentini, Giovanni (2017) 2-Arylazetidines as ligands for nicotinic acetylcholine receptors. Chemistry of Heterocyclic Compounds, 53 (3). pp. 329-334. ISSN 0009-3122 (Print), 1573-8353 (Online) (doi:10.1007/s10593-017-2061-5)

lipophilicity

Degennaro, Leonardo, Zenzola, Marina, Laurino, Annunziatina, Cavalluzzi, Maria Maddalena, Franchini, Carlo, Habtemariam, Solomon, Matucci, Rosanna, Luisi, Renzo and Lentini, Giovanni (2017) 2-Arylazetidines as ligands for nicotinic acetylcholine receptors. Chemistry of Heterocyclic Compounds, 53 (3). pp. 329-334. ISSN 0009-3122 (Print), 1573-8353 (Online) (doi:10.1007/s10593-017-2061-5)

Mexiletine

Roselli, Mariagrazia, Carocci, Alessia, Budriesi, Roberta, Micucci, Matteo, Toma, Maddalena, Di Cesare Mannelli, Lorenzo, Lovece, Angelo, Catalano, Alessia, Cavalluzzi, Maria Maddalena, Bruno, Claudio, De Palma, Annalisa, Contino, Marialessandra, Perrone, Maria Grazia, Colabufo, Nicola Antonio, Chiarini, Alberto, Franchini, Carlo, Ghelardini, Carla, Habtemariam, Solomon and Lentini, Giovanni (2016) Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues. European Journal of Medicinal Chemistry, 121. pp. 300-307. ISSN 0223-5234 (doi:10.1016/j.ejmech.2016.05.046)

MW-assisted synthesis

Roselli, Mariagrazia, Carocci, Alessia, Budriesi, Roberta, Micucci, Matteo, Toma, Maddalena, Di Cesare Mannelli, Lorenzo, Lovece, Angelo, Catalano, Alessia, Cavalluzzi, Maria Maddalena, Bruno, Claudio, De Palma, Annalisa, Contino, Marialessandra, Perrone, Maria Grazia, Colabufo, Nicola Antonio, Chiarini, Alberto, Franchini, Carlo, Ghelardini, Carla, Habtemariam, Solomon and Lentini, Giovanni (2016) Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues. European Journal of Medicinal Chemistry, 121. pp. 300-307. ISSN 0223-5234 (doi:10.1016/j.ejmech.2016.05.046)

neurodegeneration

Degennaro, Leonardo, Zenzola, Marina, Laurino, Annunziatina, Cavalluzzi, Maria Maddalena, Franchini, Carlo, Habtemariam, Solomon, Matucci, Rosanna, Luisi, Renzo and Lentini, Giovanni (2017) 2-Arylazetidines as ligands for nicotinic acetylcholine receptors. Chemistry of Heterocyclic Compounds, 53 (3). pp. 329-334. ISSN 0009-3122 (Print), 1573-8353 (Online) (doi:10.1007/s10593-017-2061-5)

nicotinic acetylcholine receptors

Degennaro, Leonardo, Zenzola, Marina, Laurino, Annunziatina, Cavalluzzi, Maria Maddalena, Franchini, Carlo, Habtemariam, Solomon, Matucci, Rosanna, Luisi, Renzo and Lentini, Giovanni (2017) 2-Arylazetidines as ligands for nicotinic acetylcholine receptors. Chemistry of Heterocyclic Compounds, 53 (3). pp. 329-334. ISSN 0009-3122 (Print), 1573-8353 (Online) (doi:10.1007/s10593-017-2061-5)

P-glycoprotein

Roselli, Mariagrazia, Carocci, Alessia, Budriesi, Roberta, Micucci, Matteo, Toma, Maddalena, Di Cesare Mannelli, Lorenzo, Lovece, Angelo, Catalano, Alessia, Cavalluzzi, Maria Maddalena, Bruno, Claudio, De Palma, Annalisa, Contino, Marialessandra, Perrone, Maria Grazia, Colabufo, Nicola Antonio, Chiarini, Alberto, Franchini, Carlo, Ghelardini, Carla, Habtemariam, Solomon and Lentini, Giovanni (2016) Synthesis, antiarrhythmic activity, and toxicological evaluation of mexiletine analogues. European Journal of Medicinal Chemistry, 121. pp. 300-307. ISSN 0223-5234 (doi:10.1016/j.ejmech.2016.05.046)

pain

Degennaro, Leonardo, Zenzola, Marina, Laurino, Annunziatina, Cavalluzzi, Maria Maddalena, Franchini, Carlo, Habtemariam, Solomon, Matucci, Rosanna, Luisi, Renzo and Lentini, Giovanni (2017) 2-Arylazetidines as ligands for nicotinic acetylcholine receptors. Chemistry of Heterocyclic Compounds, 53 (3). pp. 329-334. ISSN 0009-3122 (Print), 1573-8353 (Online) (doi:10.1007/s10593-017-2061-5)

Phenethylamines

Roselli, Mariagrazia, Cavalluzzi, Maria Maddalena, Bruno, Claudio, Lovece, Angelo, Carocci, Alessia, Franchini, Carlo, Habtemariam, Solomon and Lentini, Giovanni (2016) Synthesis and evaluation of berberine derivatives and analogues as potential anti-acetylcholinesterase and antioxidant agents. Phytochemistry Letters, 18. pp. 150-156. ISSN 1874-3900 (Print), 1876-7486 (Online) (doi:10.1016/j.phytol.2016.10.005)

schizophrenia

Degennaro, Leonardo, Zenzola, Marina, Laurino, Annunziatina, Cavalluzzi, Maria Maddalena, Franchini, Carlo, Habtemariam, Solomon, Matucci, Rosanna, Luisi, Renzo and Lentini, Giovanni (2017) 2-Arylazetidines as ligands for nicotinic acetylcholine receptors. Chemistry of Heterocyclic Compounds, 53 (3). pp. 329-334. ISSN 0009-3122 (Print), 1573-8353 (Online) (doi:10.1007/s10593-017-2061-5)

smoking cessation

Degennaro, Leonardo, Zenzola, Marina, Laurino, Annunziatina, Cavalluzzi, Maria Maddalena, Franchini, Carlo, Habtemariam, Solomon, Matucci, Rosanna, Luisi, Renzo and Lentini, Giovanni (2017) 2-Arylazetidines as ligands for nicotinic acetylcholine receptors. Chemistry of Heterocyclic Compounds, 53 (3). pp. 329-334. ISSN 0009-3122 (Print), 1573-8353 (Online) (doi:10.1007/s10593-017-2061-5)