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Items where Author is "Clayton, T. Andrew"

Items where Author is "Clayton, T. Andrew"

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acetaminophen allyl formate bacteria ethionine galactosamine glucuronide hypertyrosinemia isoniazid liver Magic Angle Spinning metabolomics metabonomics NMR spectroscopy Nuclear Magnetic Resonance Orthogonal-Partial Least Squares p-cresol Partial Least Squares pattern recognition personalised healthcare pharmacometabonomics plasma prediction rat sulfate thioacetamide tyrosine aminotransferase urine
Number of items: 29.

acetaminophen

Clayton, T. Andrew, Baker, David, Lindon, John C., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2009) Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 106 (34). pp. 14728-14733. ISSN 0027-8424 (Print), 1091-6490 (Online) (doi:https://doi.org/10.1073/pnas.0904489106)

allyl formate

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

bacteria

Clayton, T. Andrew, Baker, David, Lindon, John C., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2009) Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 106 (34). pp. 14728-14733. ISSN 0027-8424 (Print), 1091-6490 (Online) (doi:https://doi.org/10.1073/pnas.0904489106)

ethionine

Clayton, T. Andrew, Lindon, John C., Everett, Jeremy ORCID: 0000-0003-1550-4482 , Charuel, Claude, Hanton, Gilles, Le Net, Jean-Loic, Provost, Jean-Pierre and Nicholson, Jeremy K. (2006) Hepatotoxin-induced hypertyrosinemia and its toxicological significance. Archives of Toxicology, 81 (3). pp. 201-210. ISSN 0340-5761 (Print), 1432-0738 (Online) (doi:https://doi.org/10.1007/s00204-006-0136-7)

galactosamine

Clayton, T. Andrew, Lindon, John C., Everett, Jeremy ORCID: 0000-0003-1550-4482 , Charuel, Claude, Hanton, Gilles, Le Net, Jean-Loic, Provost, Jean-Pierre and Nicholson, Jeremy K. (2006) Hepatotoxin-induced hypertyrosinemia and its toxicological significance. Archives of Toxicology, 81 (3). pp. 201-210. ISSN 0340-5761 (Print), 1432-0738 (Online) (doi:https://doi.org/10.1007/s00204-006-0136-7)

glucuronide

Clayton, T. Andrew, Baker, David, Lindon, John C., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2009) Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 106 (34). pp. 14728-14733. ISSN 0027-8424 (Print), 1091-6490 (Online) (doi:https://doi.org/10.1073/pnas.0904489106)

hypertyrosinemia

Clayton, T. Andrew, Lindon, John C., Everett, Jeremy ORCID: 0000-0003-1550-4482 , Charuel, Claude, Hanton, Gilles, Le Net, Jean-Loic, Provost, Jean-Pierre and Nicholson, Jeremy K. (2006) Hepatotoxin-induced hypertyrosinemia and its toxicological significance. Archives of Toxicology, 81 (3). pp. 201-210. ISSN 0340-5761 (Print), 1432-0738 (Online) (doi:https://doi.org/10.1007/s00204-006-0136-7)

isoniazid

Clayton, T. Andrew, Lindon, John C., Everett, Jeremy ORCID: 0000-0003-1550-4482 , Charuel, Claude, Hanton, Gilles, Le Net, Jean-Loic, Provost, Jean-Pierre and Nicholson, Jeremy K. (2006) Hepatotoxin-induced hypertyrosinemia and its toxicological significance. Archives of Toxicology, 81 (3). pp. 201-210. ISSN 0340-5761 (Print), 1432-0738 (Online) (doi:https://doi.org/10.1007/s00204-006-0136-7)

liver

Clayton, T. Andrew, Lindon, John C., Everett, Jeremy ORCID: 0000-0003-1550-4482 , Charuel, Claude, Hanton, Gilles, Le Net, Jean-Loic, Provost, Jean-Pierre and Nicholson, Jeremy K. (2006) Hepatotoxin-induced hypertyrosinemia and its toxicological significance. Archives of Toxicology, 81 (3). pp. 201-210. ISSN 0340-5761 (Print), 1432-0738 (Online) (doi:https://doi.org/10.1007/s00204-006-0136-7)

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

Magic Angle Spinning

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

metabolomics

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

metabonomics

Clayton, T. Andrew, Lindon, John C., Cloarec, Olivier, Antti, Henrik, Charuel, Claude, Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loïc, Baker, David, Walley, Rosalind J., Everett, Jeremy ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2006) Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature, 440 (7087). pp. 1073-1077. ISSN 0028-0836 (Print), 1476-4687 (Online) (doi:https://doi.org/10.1038/nature04648)

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

NMR spectroscopy

Clayton, T. Andrew, Lindon, John C., Cloarec, Olivier, Antti, Henrik, Charuel, Claude, Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loïc, Baker, David, Walley, Rosalind J., Everett, Jeremy ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2006) Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature, 440 (7087). pp. 1073-1077. ISSN 0028-0836 (Print), 1476-4687 (Online) (doi:https://doi.org/10.1038/nature04648)

Nuclear Magnetic Resonance

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

Orthogonal-Partial Least Squares

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

p-cresol

Clayton, T. Andrew, Baker, David, Lindon, John C., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2009) Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 106 (34). pp. 14728-14733. ISSN 0027-8424 (Print), 1091-6490 (Online) (doi:https://doi.org/10.1073/pnas.0904489106)

Partial Least Squares

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

pattern recognition

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

personalised healthcare

Clayton, T. Andrew, Lindon, John C., Cloarec, Olivier, Antti, Henrik, Charuel, Claude, Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loïc, Baker, David, Walley, Rosalind J., Everett, Jeremy ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2006) Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature, 440 (7087). pp. 1073-1077. ISSN 0028-0836 (Print), 1476-4687 (Online) (doi:https://doi.org/10.1038/nature04648)

pharmacometabonomics

Clayton, T. Andrew, Lindon, John C., Cloarec, Olivier, Antti, Henrik, Charuel, Claude, Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loïc, Baker, David, Walley, Rosalind J., Everett, Jeremy ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2006) Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature, 440 (7087). pp. 1073-1077. ISSN 0028-0836 (Print), 1476-4687 (Online) (doi:https://doi.org/10.1038/nature04648)

plasma

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

prediction

Clayton, T. Andrew, Lindon, John C., Cloarec, Olivier, Antti, Henrik, Charuel, Claude, Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loïc, Baker, David, Walley, Rosalind J., Everett, Jeremy ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2006) Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature, 440 (7087). pp. 1073-1077. ISSN 0028-0836 (Print), 1476-4687 (Online) (doi:https://doi.org/10.1038/nature04648)

rat

Clayton, T. Andrew, Lindon, John C., Everett, Jeremy ORCID: 0000-0003-1550-4482 , Charuel, Claude, Hanton, Gilles, Le Net, Jean-Loic, Provost, Jean-Pierre and Nicholson, Jeremy K. (2006) Hepatotoxin-induced hypertyrosinemia and its toxicological significance. Archives of Toxicology, 81 (3). pp. 201-210. ISSN 0340-5761 (Print), 1432-0738 (Online) (doi:https://doi.org/10.1007/s00204-006-0136-7)

sulfate

Clayton, T. Andrew, Baker, David, Lindon, John C., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2009) Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 106 (34). pp. 14728-14733. ISSN 0027-8424 (Print), 1091-6490 (Online) (doi:https://doi.org/10.1073/pnas.0904489106)

thioacetamide

Clayton, T. Andrew, Lindon, John C., Everett, Jeremy ORCID: 0000-0003-1550-4482 , Charuel, Claude, Hanton, Gilles, Le Net, Jean-Loic, Provost, Jean-Pierre and Nicholson, Jeremy K. (2006) Hepatotoxin-induced hypertyrosinemia and its toxicological significance. Archives of Toxicology, 81 (3). pp. 201-210. ISSN 0340-5761 (Print), 1432-0738 (Online) (doi:https://doi.org/10.1007/s00204-006-0136-7)

tyrosine aminotransferase

Clayton, T. Andrew, Lindon, John C., Everett, Jeremy ORCID: 0000-0003-1550-4482 , Charuel, Claude, Hanton, Gilles, Le Net, Jean-Loic, Provost, Jean-Pierre and Nicholson, Jeremy K. (2006) Hepatotoxin-induced hypertyrosinemia and its toxicological significance. Archives of Toxicology, 81 (3). pp. 201-210. ISSN 0340-5761 (Print), 1432-0738 (Online) (doi:https://doi.org/10.1007/s00204-006-0136-7)

urine

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

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