Wet granulation; DoE; QbD; Dissolution rate; Specific surface area; Water sorption

Maniruzzaman, Mohammed, Ross, Steven A., Dey, Tumpa, Nair, Arun, Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Douroumis, Dennis ORCID: 0000-0002-3782-0091 (2017) A quality by design (QbD) twin–screw extrusion wet granulation approach for processing water insoluble drugs. International Journal of Pharmaceutics, 526 (1-2). pp. 496-505. ISSN 0378-5173 (doi:https://doi.org/10.1016/j.ijpharm.2017.05.020)