KRAS, mutations, HCT116, cells, colorectal cancer, metabonomics, metabolomics, metabolic profiling, NMR

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy ORCID: 0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-021-01852-w)

KRAS, mutations, SW48, cells, colorectal cancer, metabonomics, metabolomics, metabolic profiling, NMR

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy ORCID: 0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-020-01674-2)

Metabonomics; Pharmacometabonomics; Metabolomics; Pharmacometabolomics; Prediction of PK; Metabolic profiling

Varshavi, Dorsa, Varshavi, Dorna and Everett, Jeremy ORCID: 0000-0003-1550-4482 (2016) The role of pharmacometabonomics in predicting drug pharmacokinetics. International Journal of Pharmacokinetics, 1 (1). pp. 5-8. ISSN 2053-0846 (Print), 2053-0854 (Online) (doi:https://doi.org/10.4155/ipk-2016-0010)

antibiotic; gut microbiome; metabolite; NMR (nuclear magnetic resonance) spectroscopy; stomach; urine

Veeravalli, Sunil, Varshavi, Dorsa, Scott, Flora H, Varshavi, Dorna, Pullen, Francis, Veselkov, Kirill, Phillips, Ian R, Everett, Jeremy ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth (2022) Treatment of wild-type mice with 2,3-butanediol, a urinary biomarker of Fmo5-/- mice, decreases plasma cholesterol and epididymal fat deposition. Frontiers in Physiology, 13:859681. pp. 1-13. ISSN 1664-042X (Online) (doi:https://doi.org/10.3389/fphys.2022.859681)