endocytosis, nanomedicine, endosome, lysosome, trafficking, lysosomotropic delivery, endosomotropic delivery

Duncan, Ruth and Richardson, Simon ORCID: 0000-0002-7927-0649 (2012) Endocytosis and intracellular trafficking as gateways for nanomedicine delivery: opportunities and challenges. Molecular Pharmaceutics, 9 (9). pp. 2380-2402. ISSN 1543-8384 (Print), 1543-8392 (Online) (doi:https://doi.org/10.1021/mp300293n)

endocytosis, polymer conjugates, nanomedicine, intracellular trafficking

Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Wallom, Kerri-Lee, Ferguson, Elaine L., Deacon, Samuel P.E., Davies, Matthew W., Powell, Alison J., Piper, Robert C. and Duncan, Ruth (2008) The use of fluorescence microscopy to define polymer localisation to the late endocytic compartments in cells that are targets for drug delivery. Journal of Controlled Release, 127 (1). pp. 1-11. ISSN 0168-3659 (doi:https://doi.org/10.1016/j.jconrel.2007.12.015)

endosomolytic polymer, poly(amidoamine), subcellular fractionation

Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 , Pattrick, Nicola G., Lavignac, Nathalie, Ferruti, Paolo and Duncan, Ruth (2009) Intracellular fate of bioresponsive poly(amidoamine)s in vitro and in vivo. Journal of Controlled Release, 142 (1). pp. 78-88. ISSN 0168-3659 (doi:https://doi.org/10.1016/j.jconrel.2009.09.025)

highly cited research articles, Journal of Controlled Release

Peppas, Nicholas A., Duncan, Ruth, Wnek, Gary E., Hoffman, Allan E., Gao, Guang Hui, Kim, Sung Wan, Lee, Doo Sung, Hadjiargyrou, Michael, Touitou, Elka, Ainbinder, Denize, Mumper, Russell, Rolland, Alain, Niidome, Takuro, Labhasetwar, Vinod, Liu, Shi, Zhou, Guangyuan, Huang, Yubin, Xie, Zhigang, Jing, Xiabin, Csaba, Noemi, Alonso, Maria Jose, Ali, Omar, Mooney, David J., Lönn, Peter, Dowdy, Steven F., Feng, Si-Shen, Gao, Jinming, Lee, Eun Seong, Na, Kun, Bae, You Han, Zentner, Gaylen M., Kim, Hyesung, Yoo, Hyuk Sang, Nakayama, Masamichi, Okano, Teruo, Liao, Zi-Xian, Chuang, Er-Yuan, Hsiao, Chun-Wen, Sung, Hsing-Wen, Cabral, Horacio, Kataoka, Kazunori, Nair, Praful R., Discher, Dennis and Mitragotri, Samir (2014) Highly cited research articles in Journal of Controlled Release: Commentaries and perspectives by authors. Journal of Controlled Release, 190. pp. 29-74. ISSN 0168-3659 (doi:https://doi.org/10.1016/j.jconrel.2014.07.012)

nanotechnology, nanomedicines, new therapies

Duncan, Ruth (2012) Decoding the hype and fear of nanomedicines. Pharmaceutical Technology Europe, 24 (2). ISSN 1753-7967 (Print), 0164-6826 (Online)

polymer therapeutics, cancer, PLA2, dextrin, anticancer conjugates, nanomedicines, PUMPT

Ferguson, Elaine L., Richardson, Simon C.W. ORCID: 0000-0002-7927-0649 and Duncan, Ruth (2010) Studies on the mechanism of action of dextrin−phospholipase A₂and its suitability for use in combination therapy. Molecular Pharmaceutics, 7 (2). pp. 510-521. ISSN 1543-8384 (Print), 1543-8392 (Online) (doi:https://doi.org/10.1021/mp900232a)

polymer therapeutics, critical quality attributes, PEGylated proteins, polymer–drug conjugates, block copolymer micelles

Duncan, Ruth (2014) Polymer therapeutics: Top 10 selling pharmaceuticals — What next? Journal of Controlled Release, 190. pp. 371-380. ISSN 0168-3659 (doi:https://doi.org/10.1016/j.jconrel.2014.05.001)