Amorphous; Continuous manufacturing; Energy dispersive X-ray; Oral strips; Surface analysis

Maniruzzaman, Mohammed, Farias, Smirna, Slipper, Ian J., Boateng, Joshua S. ORCID: 0000-0002-6310-729X , Chowdhry, Babur Z., Nair, Arun and Douroumis, Dennis ORCID: 0000-0002-3782-0091 (2016) Development and optimization of ketoconazole oral strips by means of continuous hot-melt extrusion processing. Journal of Pharmacy and Pharmacology, 68 (7). pp. 890-900. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1111/jphp.12569)

Extrusion; Solid dispersions; Excipients; Drug – excipient interactions dissolution.

Maniruzzaman, M., Ross, S.A., Islam, M.T, Scoutaris, N., Nair, A. and Douroumis, Dennis ORCID: 0000-0002-3782-0091 (2017) Increased dissolution rates of tranilast solid dispersions extruded with inorganic excipients. Drug Development and Industrial Pharmacy, 43 (6). pp. 947-957. ISSN 0363-9045 (Print), 1520-5762 (Online) (doi:https://doi.org/10.1080/03639045.2017.1287716)

Granulations; DoE; QbD; Dissolutions; Twin screw; Raman; DVS

Maniruzzaman, Mohammed, Nair, Arun, Renault, Maxcene, Nandi, Uttom ORCID: 0000-0003-1777-3862 , Scoutaris, Nicholaos, Farnish, Richard, Bradley, Mike, Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Douroumis, Dennis ORCID: 0000-0002-3782-0091 (2015) Continuous twin-screw granulation for enhancing the dissolution of poorly water soluble drug. International Journal of Pharmaceutics Special Issue on "Continuous Manufacturing and Process Analytical Tools”, 496 (1). ISSN 0378-5173 (Print), 1873-3476 (Online) (doi:https://doi.org/10.1016/j.ijpharm.2015.09.025)

Inorganic excipients; Solid dispersions; Continuous extrusion

Maniruzzaman, M., Nair, A., Scoutaris, N., Bradley, Michael S.A., Snowden, M.J. ORCID: 0000-0002-1087-2692 and Douroumis, D. ORCID: 0000-0002-3782-0091 (2015) One-step continuous extrusion process for the manufacturing of solid dispersions. International Journal of Pharmaceutics Special Issue on "Continuous Manufacturing and Process Analytical Tools”, 496 (1). pp. 42-51. ISSN 0378-5173 (Print), 1873-3476 (Online) (doi:https://doi.org/10.1016/j.ijpharm.2015.09.048)

Wet granulation; DoE; QbD; Dissolution rate; Specific surface area; Water sorption

Maniruzzaman, Mohammed, Ross, Steven A., Dey, Tumpa, Nair, Arun, Snowden, Martin J. ORCID: 0000-0002-1087-2692 and Douroumis, Dennis ORCID: 0000-0002-3782-0091 (2017) A quality by design (QbD) twin–screw extrusion wet granulation approach for processing water insoluble drugs. International Journal of Pharmaceutics, 526 (1-2). pp. 496-505. ISSN 0378-5173 (doi:https://doi.org/10.1016/j.ijpharm.2017.05.020)