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Quantum dots synthesis and biological applications as imaging and drug delivery systems

Quantum dots synthesis and biological applications as imaging and drug delivery systems

Obonyo, Onyechi, Fisher, Emma, Edwards, Mark and Douroumis, Dennis (2010) Quantum dots synthesis and biological applications as imaging and drug delivery systems. Critical Reviews in Biotechnology, 30 (4). pp. 283-301. ISSN 0738-8551 (Print), 1549-7801 (Online) (doi:https://doi.org/10.3109/07388551.2010.487184)

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Abstract

Semiconductor quantum dots (QDs) synthesized by metal ions and colloid stabilizers have been explored as promising probes in advanced imaging techniques, tumor diagnostic agents, and drug delivery systems. The ability to modulate QDs surface chemistry through particle—shape control, surface coating, and surface functionalization—has rendered them a valuable tool in biological sciences. The tremendous advances in nanotechnology revealed the unique properties of QD crystals in both in vitro and in vivo conditions. In this review, we summarize the recent trends in QD synthesis, surface modification, and biological applications particularly for cancer targeting and treatment.

Item Type: Article
Uncontrolled Keywords: quantum dot, nanoparticles, bioconjugation, molecular imaging, targeting
Subjects: Q Science > Q Science (General)
T Technology > TK Electrical engineering. Electronics Nuclear engineering
Q Science > QD Chemistry
Q Science > QC Physics
Faculty / Department / Research Group: Faculty of Engineering & Science
Faculty of Engineering & Science > Department of Pharmaceutical, Chemical & Environmental Sciences
Related URLs:
Last Modified: 17 Oct 2016 09:10
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
Selected for GREAT 2019: None
URI: http://gala.gre.ac.uk/id/eprint/3627

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