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Enamael Remineralisation by Arginine-Calcium Carbonate Toothpaste

Enamael Remineralisation by Arginine-Calcium Carbonate Toothpaste

Hardy, Benjamin J., Coleman, Aimee A., Güçlü, Zeynep A. and Coleman, Nichola J. (2018) Enamael Remineralisation by Arginine-Calcium Carbonate Toothpaste. In: UKSB 2018 Annual Meeting, 28th & 29th June 2018, University of Bath, UK. (In Press)

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Abstract

White spot lesions (WSLs) are the first visual indication that the dynamic processes that maintain healthy tooth enamel have shifted in favour of demineralisation. It is possible to reverse this early stage of enamel caries with good oral hygiene and home-use products that enhance the bioavailability of salivary calcium, phosphate and fluoride species. Arginine (C6H14N4O2), a conditionally essential α-amino acid, is metabolised by oral bacteria to generate ammonia which protects enamel from acid-erosion. It also forms complexes with Ca2+ ions which increase the bioavailability of calcium and promote remineralisation. The present in vitro study investigates the potential of a commercial arginine- and calcium carbonate-bearing toothpaste (Colgate Sensitive Pro-Relief, Colgate-Palmolive (UK) Limited) to repair WSLs in human enamel under optimum and aggressive acid-challenge conditions.

Item Type: Conference or Conference Paper (Poster)
Uncontrolled Keywords: Remineralisation, toothpaste, enamel erosion, arginine
Subjects: Q Science > QD Chemistry
R Medicine > RK Dentistry
Faculty / Department / Research Group: Faculty of Engineering & Science
Faculty of Engineering & Science > Department of Pharmaceutical, Chemical & Environmental Sciences
Last Modified: 08 Dec 2018 23:07
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
Selected for GREAT 2019: None
URI: http://gala.gre.ac.uk/id/eprint/20410

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