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Enamael Protection by Hydroxyapatite Toothpaste

Enamael Protection by Hydroxyapatite Toothpaste

Coleman, Aimee A., Hardy, Benjamin J., Güçlü, Zeynep A. and Coleman, Nichola J. (2018) Enamael Protection by Hydroxyapatite Toothpaste. In: UKSB 2018 Annual Meeting, 28th & 29th June 2018, University of Bath, UK. (In Press)

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Abstract

Tooth enamel comprises ∼90% substituted hydroxyapatite (Ca10(PO4)6(OH)2), HAP, which is continually subjected to consecutive cycles of dissolution and recrystallisation. Initial dental caries is denoted by non-cavitated white spot lesions (WSLs) when net demineralisation occurs. Commercial products such as toothpastes, mouthwashes and chewing gums that release bioavailable calcium, phosphate and/or fluoride species have been shown to facilitate the remineralisation and repair of initial WSLs. In this respect, synthetic HAP particles can be incorporated into toothpastes to exploit both their abrasive and remineralising properties. The present study investigates the potential of a toothpaste containing micron-sized HAP particles (mirasensitive hap+®, Hager Werken, Germany) to repair WSLs in human enamel under optimum pH-neutral conditions and to protect the enamel exposed to an aggressive acid-challenge regime in vitro.

Item Type: Conference or Conference Paper (Poster)
Uncontrolled Keywords: Hydroxyapatite, toothpaste, remineralisation, enamel erosion
Subjects: R Medicine > RK Dentistry
Faculty / Department / Research Group: Faculty of Engineering & Science
Faculty of Engineering & Science > Department of Pharmaceutical, Chemical and Environmental Sciences
Last Modified: 27 Sep 2019 12:00
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
Selected for GREAT 2019: None
URI: http://gala.gre.ac.uk/id/eprint/20409

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