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Statistical physics of vaccination

Statistical physics of vaccination

Wang, Zhen, Bauch, Chris T., Bhattacharyya, Samit, d'Onofrio, Alberto, Manfredi, Piero, Perc, Matjaž, Perra, Nicola, Salathé, Marcel and Zhao, Dawei (2016) Statistical physics of vaccination. Physics Reports, 664. pp. 1-113. ISSN 0370-1573 (doi:https://doi.org/10.1016/j.physrep.2016.10.006)

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Abstract

Historically, infectious diseases caused considerable damage to human societies, and they continue to do so today. To help reduce their impact, mathematical models of disease transmission have been studied to help understand disease dynamics and inform prevention strategies. Vaccination–one of the most important preventive measures of modern times–is of great interest both theoretically and empirically. And in contrast to traditional approaches, recent research increasingly explores the pivotal implications of individual behavior and heterogeneous contact patterns in populations. Our report reviews the developmental arc of theoretical epidemiology with emphasis on vaccination, as it led from classical models assuming homogeneously mixing (mean-field) populations and ignoring human behavior, to recent models that account for behavioral feedback and/or population spatial/social structure. Many of the methods used originated in statistical physics, such as lattice and network models, and their associated analytical frameworks. Similarly, the feedback loop between vaccinating behavior and disease propagation forms a coupled nonlinear system with analogs in physics. We also review the new paradigm of digital epidemiology, wherein sources of digital data such as online social media are mined for high-resolution information on epidemiologically relevant individual behavior. Armed with the tools and concepts of statistical physics, and further assisted by new sources of digital data, models that capture nonlinear interactions between behavior and disease dynamics offer a novel way of modeling real-world phenomena, and can help improve health outcomes. We conclude the review by discussing open problems in the field and promising directions for future research.

Item Type: Article
Additional Information: Statistical physics of vaccination
Uncontrolled Keywords: Epidemiology; Vaccination; Human behavior; Complex networks; Data
Subjects: R Medicine > RA Public aspects of medicine > RA0421 Public health. Hygiene. Preventive Medicine
Faculty / Department / Research Group: Faculty of Business
Faculty of Business > Centre for Business Network Analysis (CBNA)
Faculty of Business > Networks and Urban Systems Centre (NUSC) > Centre for Business Network Analysis (CBNA)
Faculty of Business > Department of International Business & Economics
Last Modified: 16 Apr 2019 15:54
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: GREAT e
Selected for GREAT 2019: GREAT 2
URI: http://gala.gre.ac.uk/id/eprint/16165

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