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Multifunctional small molecular weight compounds from Peltiphyllum Peltatum: From antioxicant to neuroprotection and antidiabetic effects

Multifunctional small molecular weight compounds from Peltiphyllum Peltatum: From antioxicant to neuroprotection and antidiabetic effects

Habtemariam, S. (2012) Multifunctional small molecular weight compounds from Peltiphyllum Peltatum: From antioxicant to neuroprotection and antidiabetic effects. Planta Medica, 11 (78):PD4. ISSN 0032-0943 (Print), 1439-0221 (Online) (doi:https://doi.org/10.1055/s-0032-1320362)

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Abstract

An imbalance between the production of reactive oxygen species (ROS) and antioxidant defences is considered to be an important pathogenic factor for the development of a variety of disease conditions including cancer, neurodegenerative diseases, aging, diabetes and inflammation [1]. While antioxidant compounds offer some benefit in these disease conditions, multifunctional compounds acting at multiple targets of these diseases have tremendous therapeutic potential. In this communication, a case study on one ornamental and edible plant native the USA, Peltiphyllum peltatum, is presented. The leaves [2,3] and rhizomes of this plant are source of various antioxidant flavonoids (aglycones and glycosides) and gallic acid derivatives. The differenzial activity of these isolated compounds in cellular and cell free antioxidant assays together with potential neuroprotection and antidiabetic effects are discussed.

Item Type: Article
Uncontrolled Keywords: molecular weight, Peltiphyllum Peltatum, antioxicant, neuroprotection, antidiabetic
Subjects: Q Science > QK Botany
R Medicine > RV Botanic, Thomsonian, and eclectic medicine
Faculty / Department / Research Group: Faculty of Engineering & Science
Faculty of Engineering & Science > Department of Pharmaceutical, Chemical & Environmental Sciences
Related URLs:
Last Modified: 17 Oct 2016 09:13
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
Selected for GREAT 2019: None
URI: http://gala.gre.ac.uk/id/eprint/13453

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