Items where Faculty / School / Research Centre / Research Groups is "Medway School of Pharmacy"

University Structure (87)
- Faculty of Engineering & Science (87)
  - Medway School of Pharmacy (87)

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Number of items at this level: 473.

(TWIK-related acid-sensitive K+ channel 3)

Veale, Emma L., Hassan, Mustafa, Walsh, Yvonne, Al-Moubarak, Ehab and Mathie, Alistair (2014) Recovery of current through mutated TASK3 potassium channels underlying Birk Barel syndrome. Molecular Pharmacology, 85 (3). pp. 397-407. ISSN 0026-895X (Print), 1521-0111 (Online) (doi:https://doi.org/10.1124/mol.113.090530)

2008

Oha, Sawyin, Selleck, Paul, Temperton, Nigel J. ORCID: 0000-0002-7978-3815 , Chan, Paul K.S., Capecchi, Barbara, Manavis, Jim, Higgins, Geoff, Burrell, Christopher J. and Kok, Tuckweng (2009) Neutralizing monoclonal antibodies to different clades of Influenza A H5N1 viruses. Journal of Virological Methods, 57 (2). pp. 161-167. ISSN 0166-0934 (doi:https://doi.org/10.1016/j.jviromet.2008.12.016)

3D construct

Zhang, Bin, Chung, Se Hun, Barker, Susan, Craig, Duncan, Narayan, Roger J and Huang, Jie (2020) Direct ink writing of polycaprolactone / polyethylene oxide based 3D constructs. Progress in Natural Science: Materials International, 31. pp. 180-191. ISSN 1002-0071 (doi:https://doi.org/10.1016/j.pnsc.2020.10.001)

3D printing

Ghanizadeh Tabriz, Atabak, Gonot-Munck, Quentin, Baudoux, Arnaud, Garg, Vivek ORCID: 0000-0002-8515-4759 , Farnish, Richard, L.Katsamenis, Orestis, Hui, Ho-Wah, Boersen, Nathan, Roberts, Sandra, Jones, John and Douroumis, Dionysios ORCID: 0000-0002-3782-0091 (2023) 3D printing of personalised Carvedilol tablets using selective laser sintering. Pharmaceutics, 15 (9):2230. pp. 1-19. ISSN 1999-4923 (Online) (doi:https://doi.org/10.3390/pharmaceutics15092230)

4-substituted methylidene oxindoles

Tizzard, Graham J., Coles, Simon J., Edwards, Mark, Onyeabo, Romanus Oforbike, Allen, Mark and Spencer, John (2013) Synthesis and solid-state characterisation of 4-substituted methylidene oxindoles. Chemistry Central Journal, 7 (1):182. ISSN 1752-153X (doi:https://doi.org/10.1186/1752-153X-7-182)

5-HT

Kelley, Stephen P., Walsh, Jacqueline M., Kelly, Mark C., Muhdar, Simerjyot, Adel-Aziz, Mohammed, Barrett, Iain D. and Wildman, Scott S. (2014) Inhibition of native 5-HT3 receptor-evoked contractions in Guinea pig and mouse ileum by antimalarial drugs. European Journal of Pharmacology, 738. pp. 186-191. ISSN 0014-2999 (doi:https://doi.org/10.1016/j.ejphar.2014.05.043)

[1] These data were presented at the 3rd ESWI conference

adenovirus

Hingorani, Mohan, White, Christine L., Merron, Andrew, Peerlinck, Inge, Gore, Martin E., Slade, Andrew, Scott, Simon D., Nutting, Christopher M., Pandha, Hardev S., Melcher, Alan A., Vile, Richard G., Vassaux, Georges and Harrington, Kevin J. (2008) Inhibition of repair of radiation-induced DNA damage enhances gene expression from replication-defective adenoviral vectors. Cancer Research, 68. pp. 9771-9778. ISSN 0008-5472 (Print), 1538-7445 (Online) (doi:https://doi.org/10.1158/0008-5472.CAN-08-1911)

Muthana, Munitta, Giannoudis, Athina, Scott, Simon D., Fang, Hsin-Yu, Coffelt, Seth B., Morrow, Fiona J., Murdoch, Craig, Burton, Julian, Cross, Neil, Burke, Bernard, Mistry, Roshna, Hamdy, Freddie, Brown, Nicola J., Georgopoulos, Lindsay, Hoskin, Peter, Essand, Magnus, Lewis, Claire E. and Maitland, Norman J. (2011) Use of macrophages to target therapeutic adenovirus to human prostate tumors. Cancer Research, 71 (5). pp. 1805-1815. ISSN 0008-5472 (Print), 1538-7445 (Online) (doi:https://doi.org/10.1158/0008-5472.CAN-10-2349)

adjuvant

Temperton, Nigel J. ORCID: 0000-0002-7978-3815 , Quenelle, Debra C., Lawson, Keirissa M., Zuckerman, Jane M., Kern, Earl R., Griffiths, Paul D. and Emery, Vincent C. (2003) Enhancement of humoral immune responses to a human cytomegalovirus DNA vaccine: adjuvant effects of aluminum phosphate and CpG oligodeoxynucleotides. Journal of Medical Virology, 70 (1). pp. 86-90. ISSN 1096-9071 (on-line) (doi:https://doi.org/10.1002/jmv.10357)

adriamycin

Greco, Olga, Powell, Tanya M., Marples, Brian, Joiner, Michael C. and Scott, Simon D. (2005) Gene therapy vectors containing CArG elements from the Egr1 gene are activated by neutron irradiation, cisplatin and doxorubicin. Cancer Gene Therapy, 12 (7). pp. 655-662. ISSN 0929-1903 (Print), 1476-5500 (Online) (doi:https://doi.org/10.1038/sj.cgt.7700834)

ADRs

Phueanpinit, Pacharaporn, Jarernsiripornkul, Narumol, Pongwecharak, Juraporn and Krska, Janet (2014) Hospital pharmacists’ roles and attitudes in providing information on the safety of non-steroidal anti-inflammatory drugs in Thailand. International Journal of Clinical Pharmacy, 36 (6). pp. 1205-1212. ISSN 2210-7703 (Print), 2210-7711 (Online) (doi:https://doi.org/10.1007/s11096-014-0018-7)

adverse drug reactions

Africa

Wright, Edward, Hayman, David T.S., Vaughan, Aisling, Temperton, Nigel J. ORCID: 0000-0002-7978-3815 , Wood, James L.N., Cunningham, Andrew A., Suu-Ire, Richard, Weiss, Robin A. and Fooks, Anthony R. (2010) Virus neutralising activity of African fruit bat (Eidolon helvum) sera against emerging lyssaviruses. Virology, 408 (2). pp. 183-189. ISSN 0042-6822 (doi:https://doi.org/10.1016/j.virol.2010.09.014)

Aging

Biello, Stephany M., Bonsall, David R., Atkinson, Lynsey A., Molyneux, Penny C., Harrington, Mary E. and Lall, Gurprit S. (2018) Alterations in glutamatergic signaling contribute to the decline of circadian photoentrainment in aged mice. Neurobiology of Aging, 66. pp. 75-84. ISSN 0197-4580 (Print), 1558-1497 (Online) (doi:https://doi.org/10.1016/j.neurobiolaging.2018.02.013)

amorphous solid dispersion

Marano, Stefania ORCID: 0000-0001-7686-2924 , Ghimire, Manish, Missaghi, Shahrzad, Rajabi-Siahboomi, Ali, Craig, Duncan Q. M. ORCID: 0000-0003-1294-8993 and Barker, Susan ORCID: 0000-0003-4880-0253 (2023) Development of robust tablet formulations with enhanced drug dissolution profiles from centrifugally-spun micro-fibrous solid dispersions of itraconazole, a BCS class II drug. Pharmaceutics, 15 (3):802. pp. 1-28. ISSN 1999-4923 (Online) (doi:https://doi.org/10.3390/pharmaceutics15030802)

Anopheles coluzzii

Shepherd-Gorringe, Monique, Pettit, Marie Wendy and Hawkes, Frances ORCID: 0000-0002-0964-3702 (2024) Lethal and sublethal impacts of membrane-fed ivermectin are concentration-dependant in Anopheles coluzzii. Parasites and Vectors. ISSN 1756-3305 (In Press)

anti-bacterial agents biosynthesis

Temperton, Nigel ORCID: 0000-0002-7978-3815 (2009) Society of general microbiology - 2009 spring meeting. Idrugs, 12 (5). pp. 294-296. ISSN 1369-7056 (Print), 2040-3410 (Online)

anti-bacterial agents chemistry

Temperton, Nigel ORCID: 0000-0002-7978-3815 (2009) Society of general microbiology - 2009 spring meeting. Idrugs, 12 (5). pp. 294-296. ISSN 1369-7056 (Print), 2040-3410 (Online)

anti-bacterial agents pharmacology

Temperton, Nigel ORCID: 0000-0002-7978-3815 (2009) Society of general microbiology - 2009 spring meeting. Idrugs, 12 (5). pp. 294-296. ISSN 1369-7056 (Print), 2040-3410 (Online)

antibodies

Corti, Davide, Suguitan Jr., Amorsolo L., Pinna, Debora, Silacci, Chiara, Fernandez-Rodriguez, Blanca M., Vanzetta, Fabrizia, Santos, Celia, Luke, Catherine J., Torres-Velez, Fernando J., Temperton, Nigel J. ORCID: 0000-0002-7978-3815 , Weiss, Robin A., Sallusto, Federica, Subbarao, Kanta and Lanzavecchia, Antonio (2010) Heterosubtypic neutralizing antibodies are produced by individuals immunized with a seasonal influenza vaccine. The Journal of Clinical Investigation, 120 (5). pp. 1663-1673. ISSN 0021-9738 (Print), 1558-8238 (Online) (doi:https://doi.org/10.1172/JCI41902)

antibody

Di Genova, Cecilia, Sampson, Alex, Scott, Simon, Cantoni, Diego, Mayora-Neto, Martin, Bentley, Emma, Mattiuzzo, Giada, Wright, Edward, Derveni, Mariliza, Auld, Bethany, Harrison, Dale, Ferrara, Bill T. ORCID: 0000-0002-2163-4032 , Said, Mohamed, Selim, Arwa ORCID: 0000-0001-5552-7561 , Thompson, Elinor ORCID: 0000-0002-6434-9290 , Thompson, Craig, Carnell, George and Temperton, Nigel ORCID: 0000-0002-7978-3815 (2021) Production, titration, neutralisation and storage of SARS-CoV-2 lentiviral pseudotypes. Bio-protocol, 11 (21). pp. 1-21. ISSN 2331-8325 (doi:https://doi.org/10.21769/BioProtoc.4236)

Temperton, Nigel J. ORCID: 0000-0002-7978-3815 (2001) DNA vaccines against cytomegalovirus: current progress. International Journal of Antimicrobial Agents, 19 (3). pp. 169-172. ISSN 0924-8579 (doi:https://doi.org/10.1016/S0924-8579(01)00492-7)

antibody fragments

Hultberg, Anna, Temperton, Nigel J. ORCID: 0000-0002-7978-3815 , Rosseels, Valerie, Koenders, Mireille, Gonzalez-Pajuelo, Maria, Schepens, Bert, Ibanez, Lorena Itatı, Vanlandschoot, Peter, Schillemans, Joris, Saunders, Michael, Weiss, Robin A., Saelens, Xavier, Melero, Jose A., Verrips, C. Theo, Van Gucht, Steven and de Haard, Hans J. (2011) Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules. PLoS ONE, 6 (4). pp. 1-12. ISSN 1932-6203 (on-line) (doi:https://doi.org/10.1371/journal.pone.0017665)

antibody response

Ferrara, Francesca, Molesti, Eleonora, Böttcher-Frieberthäuser, Eva, Cattoli, Giovanni, Corti, Davide, Scott, Simon D. and Temperton, Nigel J. ORCID: 0000-0002-7978-3815 (2013) The human Transmembrane Protease Serine 2 is necessary for the production of Group 2 influenza A virus pseudotypes. Journal of Molecular and Genetic Medicine, 7 (1):55. pp. 309-314. ISSN 1747-0862 (doi:https://doi.org/10.4172/1747-0862.1000055)

antigenic drift

Cattoli, Giovanni, Milani, Adelaide, Temperton, Nigel ORCID: 0000-0002-7978-3815 , Zecchin, Bianca, Buratin, Alessandra, Molesti, Eleonora, Meherez Aly, Mona, Arafa, Abdel and Capua, Ilaria (2011) Antigenic drift in H5N1 avian influenza virus in poultry is driven by mutations in major antigenic sites of the hemagglutinin molecule analogous to those for human influenza virus. Journal of Virology, 85 (17). pp. 8718-8724. ISSN 0022-538X (Print), 1098-5514 (Online) (doi:https://doi.org/10.1128/JVI.02403-10)

antimicrobial

Zhu, Zhiqiang, Yang, Chenjie, Keyhani, Nemat O., Liu, Sen, Pu, Huili, Jia, Peisong, Wu, Dongmei, Stevenson, Philip C. ORCID: 0000-0002-0736-3619 , Fernandez-Grandon, G. Mandela ORCID: 0000-0002-2993-390X , Pan, Jieming, Chen, Yuxi, Guan, Xiayu and Qiu, Junzhi (2023) Characterization of Terpenoids from the Ambrosia Beetle Symbiont and Laurel Wilt Pathogen Harringtonia lauricola. Journal of Fungi, 9 (12):1175. ISSN 2309-608X (Online) (doi:https://doi.org/10.3390/jof9121175)

antiproliferative

antiviral

Su, Ching-Yao, Wang, Shi-Yun, Shie, Jiun-Jie, Jeng, King-Song, Temperton, Nigel J. ORCID: 0000-0002-7978-3815 , Fang, Jim-Min, Wong, Chi-Huey and Cheng, Yih-Shyun E. (2008) In vitro evaluation of neuraminidase inhibitors using the neuraminidase-dependent release assay of hemagglutinin-pseudotyped viruses. Antiviral Research, 79 (3). pp. 199-205. ISSN 0166-3542 (doi:https://doi.org/10.1016/j.antiviral.2008.03.002)

aromatic oligoamides

Hjelmgaard, Thomas, Faure, Sophie, De Santis, Emiliana, Staerk, Dan, Alexander, Bruce D., Edwards, Alison A., Taillefumier, Claude and Nielsen, John (2011) Improved solid-phase synthesis and study of arylopeptoids with conformation-directing side chains. Tetrahedron, 68 (23). pp. 4444-4454. ISSN 0040-4020 (doi:https://doi.org/10.1016/j.tet.2011.12.049)

Artificial Intelligence

Barakat, Basel ORCID: 0000-0001-9126-7613 , Steponenaite, Aiste, Lall, Gurprit S., Arshad, Kamran, Wassell, Ian J. and Keates, Simeon ORCID: 0000-0002-2826-672X (2020) Assistive technology for the visually impaired: Optimizing frame rate (freshness) to improve the performance of real-time objects detection application. In: Antona, Margherita and Stephanidis, Constantine, (eds.) Universal Access in Human-Computer Interaction. Applications and Practice. Lecture Notes in Computer Science (LNCS) (12189). Springer Nature, Switzerland, pp. 479-492. ISBN 978-3030491079 (doi:https://doi.org/10.1007/978-3-030-49108-6_34)

Assistive Technologies

asthma

Manfrin, Andrea, Thomas, Trudy and Krska, Janet (2015) Randomised evaluation of the Italian medicines use review provided by community pharmacists using asthma as a model (RE I-MUR). BMC Health Services Research, 15:171. ISSN 1472-6963 (doi:https://doi.org/10.1186/s12913-015-0791-6)

asthma patients

Manfrin, A. and Krska, J. (2014) Evaluation of feedback on medicines use reviews provided in Italy from patients with asthma. Research in Social and Administrative Pharmacy, 10 (5). e22. ISSN 1551-7411 (doi:https://doi.org/10.1016/j.sapharm.2014.07.062)

autoimmune disease

Moyes, David L., Martin, Alex, Sawcer, Stephen, Temperton, Nigel ORCID: 0000-0002-7978-3815 , Worthington, Jane, Griffiths, David J. and Venables, Patrick J. (2005) The distribution of the endogenous retroviruses HERV-K113 and HERV-K115 in health and disease. Genomics, 86 (3). pp. 337-341. ISSN 0888-7543 (doi:https://doi.org/10.1016/j.ygeno.2005.06.004)

avian H5N1 virus

Mahallawi, Waleed H., Kasbekar, Anand V., McCormick, Maxwell S., Hoschler, Katja, Temperton, Nigel ORCID: 0000-0002-7978-3815 , Leong, Samuel C., Beer, Helen, Ferrara, Francesca, McNamara, Paul S. and Zhang, Qibo (2013) Infection with 2009 H1N1 influenza virus primes for immunological memory in human nose-associated lymphoid tissue, offering cross-reactive immunity to H1N1 and avian H5N1 viruses. Journal of Virology, 87 (10). pp. 5331-5339. ISSN 0022-538X (Print), 1098-5514 (Online) (doi:https://doi.org/10.1128/JVI.03547-12)

avian influenza

Ascione, Alessandro, Capecchi, Barbara, Campitelli, Laura, Imperiale, Valentina, Flegoa, Michela, Zamboni, Silvia, Gellini, Mara, Alberini, Isabella, Pittiglio, Eliana, Donatelli, Isabella, Temperton, Nigel J. ORCID: 0000-0002-7978-3815 and Cianfriglia, Maurizio (2009) Human monoclonal antibodies in single chain fragment variable format with potent neutralization activity against influenza virus H5N1. Antiviral Research, 83 (3). pp. 238-244. ISSN 0166-3542 (doi:https://doi.org/10.1016/j.antiviral.2009.05.005)

avian influenza virus

Alberini, Isabella, Del Tordello, Elena, Fasolo, Alba, Temperton, Nigel J. ORCID: 0000-0002-7978-3815 , Galli, Grazia, Gentile, Chiara, Montomoli, Emanuele, Hilbert, Anne K., Banzhoff, Angelika, Del Giudice, Giuseppe, Donnelly, John J., Rappuoli, Rino and Capecchi, Barbara (2009) Pseudoparticle neutralization is a reliable assay to measure immunity and cross-reactivity to H5N1 influenza viruses. Vaccine, 27 (43). pp. 5998-6003. ISSN 0264-410X (doi:https://doi.org/10.1016/j.vaccine.2009.07.079)

bat

bioactive compounds

Lawrence, A.J., Afifia, R., Ahmed, M., Khalifa, S. and Paget, T. (2009) Bioactivity as an options value of sea cucumbers in the Egyptian Red Sea. Conservation Biology, 24 (1). pp. 217-225. ISSN 0888-8892 (Print), 1523-1739 (Online) (doi:https://doi.org/10.1111/j.1523-1739.2009.01294.x)

bioreductive drugs

Greco, Olga and Scott, Simon (2007) Tumor hypoxia and targeted gene therapy. International Review of Cytology, 257. pp. 181-212. ISSN 0074-7696 (doi:https://doi.org/10.1016/S0074-7696(07)57005-1)

bipolar

Walsh, Jacqueline M., Atkinson, Lynsey A., Corlett, Sarah A. and Lall, Gurprit S. (2014) An insight into light as a chronobiological therapy in affective disorders. ChronoPhysiology and Therapy, 4. pp. 79-85. ISSN 2230-2026 (doi:https://doi.org/10.2147/CPT.S56589)

bipolar charge

Hussain, Tariq, Kaialy, Waseem, Deng, Tong ORCID: 0000-0003-4117-4317 , Bradley, Mike S.A., Nokhodchi, Ali and Armour-Chélu, David (2012) A novel sensing technique for measurement of magnitude and polarity of electrostatic charge distribution across individual particles. International Journal of Pharmaceutics, 441 (1-2). pp. 781-789. ISSN 0378-5173 (doi:https://doi.org/10.1016/j.ijpharm.2012.10.002)

birds

Temperton, N. ORCID: 0000-0002-7978-3815 (2009) BirdFlu2009: Avian Influenza and Human Health. 9-10 September 2009, Oxford, UK. IDrugs, 12 (11). pp. 686-688. ISSN 1369-7056 (Print), 2040-3410 (Online)

blood mononuclear cells

Pinto, E. and Harbige, L.S. (2006) Effects of ω-6 fatty acids on human monocyte and T-cell adhesion molecule expression. In: 7th Congress of the ISSFAL, International Society for the Study of Fatty Acids & Lipids (ISSFAL 2006), 23–28 Jul 2006, Cairns, Queensland, Australia. (Unpublished)

breast cancer

Greco, O., Joiner, M.C., Doleh, A., Powell, A.D., Hillman, G. and Scott, S.D. (2006) Hypoxia- and radiation-activated Cre/loxP 'molecular switch' vectors for gene therapy of cancer. Gene Therapy, 13 (3). pp. 206-215. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3302640)

breast cancer xenografts

Lipnik, Karoline, Greco, Olga, Scott, Simon, Knapp, Elzbieta, Mayrhofer, Elisabeth, Rosenfellner, Doris, Günzburg, Walter H., Salmons, Brian and Hohenadl, Christine (2006) Hypoxia- and radiation-inducible, breast cell-specific targeting of retroviral vectors. Virology, 349 (1). pp. 121-133. ISSN 0042-6822 (doi:https://doi.org/10.1016/j.virol.2005.12.038)

breast cell-specific expression targeting

bystander effect

Greco, O., Joiner, M.C., Doleh, A. and Scott, S.D. (2005) VP22-mediated intercellular transport for suicide gene therapy under oxic and hypoxic conditions. Gene Therapy, 12 (12). pp. 974-979. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3302482)

cancer

Greco, O., Scott, S.D., Marples, B. and Dachs, D.U. (2002) Cancer gene therapy: 'delivery, delivery, delivery'. Frontiers in Bioscience, 7. d1516-d1524. ISSN 1093-9946 (Print), 1093-4715 (Online) (doi:https://doi.org/10.2741/greco)

Greco, Olga, Marples, Brian, Joiner, Michael C. and Scott, Simon D. (2003) How to overcome (and exploit) tumor hypoxia for targeted gene therapy. Journal of Cellular Physiology, 197 (3). pp. 312-325. ISSN 0021-9541 (Print), 1097-4652 (Online) (doi:https://doi.org/10.1002/jcp.10374)

Scott, S.D. and Marples, B. (2000) Comment on the use of the cre/loxP recombinase system for gene therapy vectors. Gene Therapy, 7 (19). p. 1706. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301305)

cancer gene therapy

Worthington, J., Robson, T., Scott, S. and Hirst, D. (2005) Evaluation of a synthetic CArG promoter for nitric oxide synthase gene therapy of cancer. Gene Therapy, 12 (19). pp. 1417-1423. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3302552)

cardiovascular

Saramunee, K., Krska, J., Mackridge, A., Richards, J., Suttajit, S. and Phillips-Howard, P. (2015) General public's views on pharmacy public health services: current situation and opportunities in the future. Public Health, 129 (6). pp. 705-715. ISSN 0033-3506 (doi:https://doi.org/10.1016/j.puhe.2015.04.002)

CArG

CArG element

Greco, O., Marples, B., Dachs, G.U., Williams, K.J., Patterson, A.V. and Scott, S.D. (2002) Novel chimeric gene promoters responsive to hypoxia and ionizing radiation. Gene Therapy, 9 (20). pp. 1403-1411. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301823)

CArG elements

Greco, Olga and Scott, Simon (2007) Tumor hypoxia and targeted gene therapy. International Review of Cytology, 257. pp. 181-212. ISSN 0074-7696 (doi:https://doi.org/10.1016/S0074-7696(07)57005-1)

Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2002) Molecular approaches to chemo-radiotherapy. European Journal of Cancer, 38 (2). pp. 231-239. ISSN 0959-8049 (doi:https://doi.org/10.1016/S0959-8049(01)00367-7)

Marples, B., Greco, O., Joiner, M.C. and Scott, S.D. (2003) Radiogenetic therapy: strategies to overcome tumor resistance. Current Pharmaceutical Design, 9 (26). pp. 2105-2112. ISSN 1381-6128 (Print), 1873-4286 (Online) (doi:https://doi.org/10.2174/1381612033454090)

Marples, B., Scott, S.D., Hendry, J.H., Embleton, M.J., Lashford, L.S. and Margison, G.P. (2000) Development of synthetic promoters for radiationmediated gene therapy. Gene Therapy, 7 (6). pp. 511-517. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301116)

Scott, S.D., Joiner, M.C. and Marples, B (2002) Optimizing radiation-responsive gene promoters for radiogenetic cancer therapy. Gene Therapy, 9 (20). pp. 1396-1402. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/sj.gt.3301822)

carvedilol

case studies

cell line

cell proliferation

Löschmann, Nadine, Michaelis, Martin, Rothweiler, Florian, Zehner, Richard, Cinatl, Jaroslav, Voges, Yvonne, Sharifi, Mohsen, Riecken, Kristoffer, Meyer, Jochen, von Deimling, Andreas, Fichtner, Iduna, Ghafourian, Taravat, Frank Westermann, Frank Westermann and Cinatl, Jindrich (2013) Testing of SNS-032 in a panel of human neuroblastoma cell lines with acquired resistance to a broad range of drugs. Translational Oncology, 6 (6). pp. 685-696. ISSN 1936-5233 (doi:https://doi.org/10.1593/tlo.13544)

cell viability

cell-based

Muthana, M., Scott, S.D., Farrow, N., Morrow, F., Murdoch, C., Grubb, S., Brown, N., Dobson, J. and Lewis, C.E. (2008) A novel magnetic approach to enhance the efficacy of cell-based gene therapies. Gene Therapy, 15 (12). pp. 902-910. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/gt.2008.57)

cellular receptor

Dye, Charlotte, Temperton, Nigel ORCID: 0000-0002-7978-3815 and Siddell, Stuart G. (2007) Type I feline coronavirus spike glycoprotein fails to recognize aminopeptidase N as a functional receptor on feline cell lines. Journal of General Virology, 88 (6). pp. 1753-1760. ISSN 0022-1317 (Print), 1465-2099 (Online) (doi:https://doi.org/10.1099/vir.0.82666-0)

centrifugal spinning

chemokine

chemotherapy

Greco, Olga and Scott, Simon (2007) Tumor hypoxia and targeted gene therapy. International Review of Cytology, 257. pp. 181-212. ISSN 0074-7696 (doi:https://doi.org/10.1016/S0074-7696(07)57005-1)

chloroquine

circadian

Lall, G.S., Atkinson, L.A., Corlett, S.A., Broadbridge, P.J. and Bonsall, D.R. (2012) Circadian entrainment and its role in depression: a mechanistic review. Journal of Neural Transmission, 119 (10). pp. 1085-1096. ISSN 0300-9564 (Print), 1435-1463 (Online) (doi:https://doi.org/10.1007/s00702-012-0858-z)

Circadian rhythm

circular dichroism

Edwards, Alison A., Alexander, Bruce D., Fleet, George W.J. and Tranter, George E. (2008) Spectroscopic studies of oligomers containing 2,5-trans furanoid sugar amino acids. Chirality, 20 (9). pp. 969-972. ISSN 0899-0042 (Print), 1520-636X (Online) (doi:https://doi.org/10.1002/chir.20538)

cluster randomised controlled trial (RCT)

CMV promoter

Collagen

Barrientos, Ivan J. Hall, Paladino, Eleonora, Szabó, Peter, Brozio, Sarah, Hall, Peter J., Oseghale, Charles I., Passarelli, Melissa K., Moug, Susan J., Black, Richard A., Wilson, Clive G., Zelkó, Romana and Lamprou, Dimitrios A. (2017) Electrospun collagen-based nanofibres: A sustainable material for improved antibiotic utilisation in tissue engineering applications. International Journal of Pharmaceutics, 531 (1). pp. 67-79. ISSN 0378-5173 (Print), 1873-3476 (Online) (doi:https://doi.org/10.1016/j.ijpharm.2017.08.071)

commissioning

Dewsbury, Catherine, Rodgers, Ruth and Krska, Janet (2015) Views of English pharmacists on providing public health services. Pharmacy, 3 (4). pp. 154-168. ISSN 2226-4787 (Online) (doi:https://doi.org/10.3390/pharmacy3040154)

community pharmacy

compounds

Samaras, Eleftherios G. (2012) Effect of formulation factors on the skin penetration of drugs. MPhil thesis, Universities of Kent and Greenwich.

compuestos bioactivos

conformation

conformational analysis

contractions

controlled study

coronaviru

Li, Chris Ka-fai, Wu, Hao, Yan, Huiping, Ma, Shiwu, Wang, Lili, Zhang, Mingxia, Tang, Xiaoping, Temperton, Nigel J. ORCID: 0000-0002-7978-3815 , Weiss, Robin A., Brenchley, Jason M., Douek, Daniel C., Mongkolsapaya, Juthathip, Tran, Bac-Hai, Lin, Chen-lung Steve, Screaton, Gavin R., Hou, Jin-lin, McMichael, Andrew J. and Xu, Xiao-Ning (2008) T Cell responses to whole SARS Coronavirus in humans. The Journal of Immunology, 181 (8). pp. 5490-5500. ISSN 0022-1767 (Print), 1550-6606 (Online) (doi:https://doi.org/10.4049/jimmunol.181.8.5490)

CoV

Covid-19

CpG ODN

craniofacial abnormalities

CRE recombinase

Scott, S.D., Marples, B., Hendry, J.H., Lashford, L.S., Embleton, M.J., Hunter, R.D., Howell, A. and Margison, G.P. (2000) A radiation-controlled molecular switch for use in gene therapy of cancer. Gene Therapy, 7 (13). pp. 1121-1125. (doi:https://doi.org/10.1038/sj.gt.3301223)

Cre/lox recombination

Scott, Simon D. and Greco, Olga (2004) Radiation and hypoxia inducible gene therapy systems. Cancer and Metastasis Reviews, 23 (3-4). pp. 269-276. ISSN 0167-7659 (Print), 1573-7233 (Online) (doi:https://doi.org/10.1023/B:CANC.0000031766.58614.f1)

Cre/loxP

Greco, Olga and Scott, Simon (2007) Tumor hypoxia and targeted gene therapy. International Review of Cytology, 257. pp. 181-212. ISSN 0074-7696 (doi:https://doi.org/10.1016/S0074-7696(07)57005-1)

cross-clade neutralization

cross-reactive immunity

CTL

cytomegalovirus

cytoplasmic peroxiredoxin

Wilkinson, Shane R., Temperton, Nigel J. ORCID: 0000-0002-7978-3815 , Mondragon, Angeles and Kelly, John M. (2000) Distinct mitochondrial and cytosolic enzymes mediate trypanothione-dependent peroxide metabolism in Trypanosoma cruzi. The Journal of Biological Chemistry, 275 (11). pp. 8220-8225. ISSN 0021-9258 (Print), 1083-351X (Online) (doi:https://doi.org/10.1074/jbc.275.11.8220)

d-Glucosamine HCl

Asare-Addo, Kofi, Šupuk, Enes, Al-Hamidi, Hiba, Owusu-Ware, Samuel, Nokhodchi, Ali and Conway, Barbara R. (2015) Triboelectrification and dissolution property enhancements of solid dispersions. International Journal of Pharmaceutics, 485 (1-2). pp. 306-316. ISSN 0378-5173 (doi:https://doi.org/10.1016/j.ijpharm.2015.03.013)

decision trees

Newby, Danielle, Freitas, Alex. A. and Ghafourian, Taravat (2015) Decision trees to characterise the roles of permeability and solubility on the prediction of oral absorption. European Journal of Medicinal Chemistry, 90. pp. 751-765. ISSN 0223-5234 (doi:https://doi.org/10.1016/j.ejmech.2014.12.006)

depression

dipeptide isosteres

direct ink writing

disease outbreaks

disintegration

Tawfik, Essam A, Scarpa, Mariagiovanna, Adbelhakim, Hend E, Bukhary, Haitham A, Craig, Duncan Q M, Barker, Susan A and Orlu, Mine (2021) A Potential Alternative Orodispersible Formulation to Prednisolone Sodium Phosphate Orally Disintegrating Tablets. Pharmaceutics, 13:120. ISSN 1999-4923 (doi:https://doi.org/10.3390/pharmaceutics13010120)

disordered

dissolution

dissolution enhancement

distibución

distribution

DNA

DNA repair

DNA vaccine

DNA vaccines

double-strand breaks

drug design

Temperton, Nigel ORCID: 0000-0002-7978-3815 (2009) Society of general microbiology - 2009 spring meeting. Idrugs, 12 (5). pp. 294-296. ISSN 1369-7056 (Print), 2040-3410 (Online)

drug information

Drug Release

drug resistance

drug safety

e-tongue

Egr1

Electrospinning

electrospun nanofibers

electrostatic charge

electrostatics

endectocides

endogenous retrovirus

enhancer

Chadderton, Naomi, Cowen, Rachel L., Sheppard, Freda C.D, Robinson, Suzanne, Greco, Olga, Scott, Simon D., Stratford, Ian J., Patterson, Adam V. and Williams, Kaye J. (2005) Dual responsive promoters to target therapeutic gene expression to radiation-resistant hypoxic tumour cells. International Journal of Radiation Oncology*Biology*Physics, 62 (1). pp. 213-222. ISSN 0360-3016 (doi:https://doi.org/10.1016/j.ijrobp.2005.01.031)

entrainment

enzyme activity

evaluation

extended

fatty acids

fecundity

feline aminopeptidase N

flow cytometry

foldamers

free radical scavenging

fusion proteins

Gallic acid

Civenni, G., Iodice, M. G., Nabavi, S. F., Habtemariam, S., Nabavi, S. M., Catapano, C. V. and Daglia, M. (2015) Gallic acid and methyl-3-O-methyl gallate: a comparative study on their effects on prostate cancer stem cells. RSC Advances, 5 (78). pp. 63800-63806. ISSN 2046-2069 (Online) (doi:https://doi.org/10.1039/C5RA07988H)

ganciclovir

gastrointestinal

GCV

GDEPT

gene expression

gene therapy

Coulter, J.A., McCarthy, H.O., Worthington, J., Robson, T., Scott, S. and Hirst, D.G. (2008) The radiation-inducible pE9 promoter driving inducible nitric oxide synthase radiosensitizes hypoxic tumour cells to radiation. Gene Therapy, 15 (7). pp. 495-503. ISSN 0969-7128 (Print), 1476-5462 (Online) (doi:https://doi.org/10.1038/gt.2008.7)

Greco, O., Marples, B., Wilson, G.D., Joiner, M.C. and Scott, S.D. (2005) Radiation-induced gene therapy. Radiation Research, 163 (6). pp. 707-708. ISSN 0033-7587 (Print), 1938-5404 (Online) (doi:https://doi.org/10.1667/RR3300)

Scott, Simon D. and Marples, Brian (2004) Radiation-activated antitumor vectors. In: Springer, Caroline J., (ed.) Suicide Gene Therapy: methods and reviews. Methods in Molecular Medicine (90). Humana Press Inc., New Jersey, USA, pp. 389-402. ISBN 978-0-89603-971-1 (Print), 978-1-59259-429-0 (Online) ISSN 1543-1894 (doi:https://doi.org/10.1385/1-59259-429-8:389)

gene vector

Collis, S.J., Tighe, A., Scott, S.D., Roberts, S.A., Hendry, J.H. and Margison, G.P. (2001) Ribozyme minigene-mediated RAD51 down-regulation increases radiosensitivity of human prostate cancer cells. Nucleic Acids Research, 29 (7). pp. 1534-1538. ISSN 0305-1048 (Print), 1362-4962 (Online) (doi:https://doi.org/10.1093/nar/29.7.1534)

gene-to-vaccine

Loureiro, Silvia, Ren, Junyuan, Phapugrangkul, Pongsathon, Colaco, Camilo A., Bailey, Christopher R., Shelton, Holly, Molesti, Eleonora, Temperton, Nigel J. ORCID: 0000-0002-7978-3815 , Barclay, Wendy S. and Jones, Ian M. (2010) Adjuvant-free immunization with hemagglutinin-Fc fusion proteins as an approach to influenza vaccines. Journal of Virology, 85 (6). pp. 3010-3014. ISSN 0022-538X (Print), 1098-5514 (Online) (doi:https://doi.org/10.1128/JVI.01241-10)

general public

genetic radiotherapy

GFP

Ghana

glioma

Glutamate

GPs

Krska, Janet and Manfrin, A. (2014) Pharmacist and GP views on a medicine use review pilot project conducted in Italy. Research in Social and Administrative Pharmacy, 10 (5). e38. ISSN 1551-7411 (doi:https://doi.org/10.1016/j.sapharm.2014.07.100)

group 1

Corti, Davide, Voss, Jarrod, Gamblin, Steven J., Codoni, Giosiana, Macagno, Annalisa, Jarrossay, David, Vachieri, Sebastien G., Pinna, Debora, Minola, Andrea, Vanzetta, Fabrizia, Silacci, Chiara, Fernandez-Rodriguez, Blanca M., Agatic, Gloria, Bianchi, Siro, Giacchetto-Sasselli, Isabella, Calder, Lesley, Sallusto, Federica, Collins, Patrick, Haire, Lesley F., Temperton, Nigel ORCID: 0000-0002-7978-3815 , Langedijk, Johannes P.M., Skehel, John J. and Lanzavecchia, Antonio (2011) A neutralizing antibody selected from plasma cells that binds to group 1 and group 2 influenza A hemagglutinins. Science, 333 (6044). pp. 850-856. ISSN 0036-8075 (Print), 1095-9203 (Online) (doi:https://doi.org/10.1126/science.1205669)

group 2

H1N1 infection

H3N8

Scott, Simon, Molesti, Eleonora, Temperton, Nigel ORCID: 0000-0002-7978-3815 , Ferrara, Francesca, Böttcher-Friebertshäuser, Eva and Daly, Janet (2012) The use of equine influenza pseudotypes for serological screening. Journal of Molecular and Genetic Medicine, 6. pp. 304-308. ISSN 1747-0862

H5N1

Ibanez, Lorena Itati, De Filette, Marina, Hultberg, Anna, Verrips, Theo, Temperton, Nigel ORCID: 0000-0002-7978-3815 , Weiss, Robin A., Vandevelde, Wesley, Schepens, Bert, Vanlandschoot, Peter and Saelens, Xavier (2011) Nanobodies with in vitro neutralizing activity protect mice against H5N1 influenza virus infection. The Journal of Infectious Diseases, 203 (8). pp. 1063-1072. ISSN 0022-1899 (Print), 1537-6613 (Online) (doi:https://doi.org/10.1093/infdis/jiq168)

Temperton, Nigel J. ORCID: 0000-0002-7978-3815 , Hoschler, Katja, Major, Diane, Nicolson, Carolyn, Manvell, Ruth, Hien, Vo Minh, Ha, Do Quang, de Jong, Menno, Zambon, Maria, Takeuchi, Yasuhiro and Weiss, Robin A. (2007) A sensitive retroviral pseudotype assay for influenza H5N1-neutralizing antibodies. Influenza and other respiratory viruses, 1 (3). pp. 105-112. ISSN 1750-2659 (online) (doi:https://doi.org/10.1111/j.1750-2659.2007.00016.x)

H5N1 Influenza

H5N1 virus

H7 lentiviral pseudotype

Molesti, Eleonora, Cattoli, Giovanni, Ferrara, Francesca, Böttcher-Frieberthäuser, Eva, Terregino, Calogero and Temperton, Nigel ORCID: 0000-0002-7978-3815 (2013) The production and development of H7 Influenza virus pseudotypes for the study of humoral responses against avian viruses. Journal of Molecular and Genetic Medicine, 7. pp. 315-320. ISSN 1747-0862

haemagglutinin

Harringtonia lauricola

HEK293 cells

hemagglutinin

Shelton, Holly, Roberts, Kim L., Molesti, Eleonora, Temperton, Nigel ORCID: 0000-0002-7978-3815 and Barclay, Wendy S. (2013) Mutations in hemagglutinin that affect receptor binding and pH stability increase replication of a PR8 influenza virus with H5 HA in the upper respiratory tract of ferrets and may contribute to transmissibility. Journal of General Virology, 94 (6). pp. 1220-1229. ISSN 0022-1317 (Print), 1465-2099 (Online) (doi:https://doi.org/10.1099/vir.0.050526-0)

hemagglutinins

HERV

HIF

Greco, Olga and Scott, Simon (2007) Tumor hypoxia and targeted gene therapy. International Review of Cytology, 257. pp. 181-212. ISSN 0074-7696 (doi:https://doi.org/10.1016/S0074-7696(07)57005-1)

hospital pharmacists

HPAI

HRE

Greco, Olga and Scott, Simon (2007) Tumor hypoxia and targeted gene therapy. International Review of Cytology, 257. pp. 181-212. ISSN 0074-7696 (doi:https://doi.org/10.1016/S0074-7696(07)57005-1)

HRP/IAA

HSVtk

HSVtk/GCV

human

human cell

human influenza virus

human prostate tumors

hypoxia

hypoxia responsive element

ICS

Imaging

immunity

Temperton, Nigel J. ORCID: 0000-0002-7978-3815 , Chan, Paul K., Simmons, Graham, Zambon, Maria C., Tedder, Richard S., Takeuchi, Yasuhiro and Weiss, Robin A. (2005) Longitudinally profiling neutralizing antibody response to SARS coronavirus with pseudotypes. Emerging Infectious Diseases, 11 (3). pp. 411-416. ISSN 1080-6059 (doi:https://doi.org/10.3201/eid1103.040906)

Wright, Edward, Temperton, Nigel J. ORCID: 0000-0002-7978-3815 , Marston, Denise A., McElhinney, Lorraine M., Fooks, Anthiny R. and Weiss, Robin A. (2008) Investigating antibody neutralization of lyssaviruses using lentiviral pseudotypes: a cross-species comparison. Journal of General Virology, 89 (9). pp. 2204-2213. ISSN 0022-1317 (Print), 1465-2099 (Online) (doi:https://doi.org/10.1099/vir.0.2008/000349-0)

immunization

immunological memory

immunoprophylaxis

indomethacin

inducible nitric oxide synthase

inductive sensor

infection

Influenza

Ferrara, Francesca, Molesti, Eleonora, Scott, Simon, Cattoli, Giovanni and Temperton, Nigel ORCID: 0000-0002-7978-3815 (2017) The use of hyperimmune chicken reference sera is not appropriate for the validation of influenza pseudotype neutralization assays. Pathogens, 6 (4). ISSN 2076-0817 (Print), 2076-0817 (Online) (doi:https://doi.org/10.3390/pathogens6040045)

influenza A virus

influenza vaccination

influenza vaccine

influenza virus

Information Freshness

ink rheology

iNOS

intellectual disability

intestinal absorption

intracellular cytokine staining

Iron superoxide dismutase

Temperton, Nigel ORCID: 0000-0002-7978-3815 , Wilkinson, Shane R. and Kelly, John M. (1996) Cloning of an Fe-superoxide dismutase gene homologue from Trypanosoma cruzi. Molecular and Biochemical Parasitology, 76 (1-2). pp. 339-343. ISSN 0166-6851 (doi:https://doi.org/10.1016/0166-6851(95)02553-7)

Italy

itraconazole

Ivermectin

Knoevenagel condensation

lagos bat virus

laurel wilt

live SARS virus

Llama

LPAI

lyssavirus

lyssaviruses

Machine Learning

macrophages

magnetic

MAP kinase

material characterisation

medicine use review (MUR)

medicines

medicines use review

mefloquine

membrane potentials

methyl-3-O-methyl gallate

micro-neutralization

microassay

microfibre

mitochondrial membrane potential

mitochondrial peroxiredoxin

mixed-methods

molecular switch

mouse model

multiple sclerosis

muscarinic M3

muscle hypotonia

mutation

mutations

Nab

nanobodies

neuraminidase inhibitor

neuroblastoma

neutralisation

Neutralization

neutralizing Ab

neutralizing antibody

neutralizing mAbs

neutralizing titers

NMDA

non-photic SAD

nonseasonal

nonsteroidal anti-inflammatory drugs

NR2B

NSAIDs

oncology

Ophiostomales

options value

oral

oral formulation

ordered

orodispersible films (ODFs)

overexpression

Temperton, Nigel J. ORCID: 0000-0002-7978-3815 , Wilkinson, Shane R., Meyer, David J. and Kelly, John M. (1998) Overexpression of superoxide dismutase in Trypanosoma cruzi results in increased sensitivity to the trypanocidal agents gentian violet and benznidazole. Molecular and Biochemical Parasitology, 96 (1-2). pp. 167-176. ISSN 0166-6851 (doi:https://doi.org/10.1016/S0166-6851(98)00127-3)

Oxidative stress

pandemic potential

pandemic vaccine

particulate material

PBMC

pE9

pepino de mar

peptidomimetics

peptoids

peripheral blood mononuclear cell

permeability

peroxide-mediated damage

personalised medicines

pH stability

pharmacist opinions

pharmacists

pharmacy public health services

photic

Physicochemical Characterisation

plasma cells

polycaprolactone

polyethylene oxide

polymorphism

poorly water-soluble drug

Portugal in September

potassium channels

powder blending

PR8 influenza virus

prednisolone

prevention & control

primary care

product development

Zhu, Valentine, Giddaluru, Muni, El Souri, Mohammed ORCID: 0000-0002-9651-7770 and Gao, Xiaoyu ORCID: 0000-0001-5625-3654 (2022) An approach to determining the need for integrating quality management into industrial PLM implementation. Procedia CIRP, 109. pp. 490-495. ISSN 2212-8271 (doi:https://doi.org/10.1016/j.procir.2022.05.283)

product lifecycle management

product quality

promoter conversion

promoters

prostate

prostate cancer

protease cleavage

protection

protein expression

protein phosphorylation

protein structure

proteins

pseudoparticle neutralization assay

pseudotype

pseudotype assay

pseudotype serology

pseudotype virus

Pseudotypes

public health

QSAR

QSAR analysis

Samaras, Eleftherios G. (2012) Effect of formulation factors on the skin penetration of drugs. MPhil thesis, Universities of Kent and Greenwich.

quality systems

quantitative structure-activity relationship

Samaras, Eleftherios G. (2012) Effect of formulation factors on the skin penetration of drugs. MPhil thesis, Universities of Kent and Greenwich.

quinine

rabies

rabies vaccines

rabies virus

RAD51

radiation

Greco, Olga and Scott, Simon (2007) Tumor hypoxia and targeted gene therapy. International Review of Cytology, 257. pp. 181-212. ISSN 0074-7696 (doi:https://doi.org/10.1016/S0074-7696(07)57005-1)

radiation-responsive elements

radiotherapy

Real-time Objects Detection

receptor

receptor binding

respiratory syncytial virus

retroviral pseudotypes

retroviral vector

reviews

RNA interference

RNA synthesis

SAD

SARS

SARS-CoV-2

scFv

sea cucumber

secondary metabolite

selective laser sintering

serological methods

Serology

severe acute respiratory syndrome

SFC

Sjogren’s syndrome

skin permeation

Samaras, Eleftherios G. (2012) Effect of formulation factors on the skin penetration of drugs. MPhil thesis, Universities of Kent and Greenwich.

solid dispersions

solid state x-ray crystallography

solid-phase synthesis

solubility

solvent-casting

spot forming cell

SRF

SRH

Standards

stem cells

storage

sucrose

sugar amino acids

suicide gene

suicide gene therapy

Greco, Olga and Scott, Simon (2007) Tumor hypoxia and targeted gene therapy. International Review of Cytology, 257. pp. 181-212. ISSN 0074-7696 (doi:https://doi.org/10.1016/S0074-7696(07)57005-1)

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