Items where Author is "Mitchell, J.C."

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(ITC) 2D correlation spectroscopy 4-Vinylpyridine acquisition amorphous antimicrobial properties base catalysed hydrolysis of methyl paraben buccal delivery calorimetric data calorimetry catalysis catalysts cationic colloidal microgel chemical modification chirality chitosan co-polymer co-polymer microgels colloidal microgels column liquid chromatography compositional analysis correlation crosslinked pullulan crystalline Cyclodextrin complex Deformation dendrimers detector calibration dissolution DLS drug drug carriers dynamic nuclear polarization method edible film electrophoretic mobility ELSD enantiomeric excess enzymes ethylene oxide evaporative light-scattering detector films flow calorimetry fracture toughness freeze-dried materials freeze-dried wafers FT-Raman glycine Heckel equation humidity imidazolide coupling isothermal isothermal flow isothermal microcalorimetry isothermal titration calorimetry ITC LC-MS/MS assays Linear regression log P mechanical properties metolose micellar liquid chromatography micellar systems micelle size micelles Michaelis-Menten kinetics Michaelis-Menten parameters microgel swelling behavior microgels MLC monomer composition nanoindentation NMR spectroscopy NSAID oxide block copolymers paediatric particle size partitioning PDMS membrane permeability pH and temperature responsive swelling pharmaceutical -------------------------------------------------------------------------------- pharmaceutical crystals pharmaceutical products phthalate ester phthalate esters polyelectrolyte polysaccharide pullulan potentiometric titration powder flow behaviour propylene protonation PXRD QSPR Raman images relaxation salt formation saturation determination single crystals sodium dodecyl sulphate solid state Raman spectra sucrose surface energy surface-active agents thermodynamic thermodynamic considerations thermodynamics times triacetin True density volume study xylose Yield pressure

Number of items: 120.

(ITC)

Waters, Laura.J., Leharne, S.A. and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2005) Saturation determination of micellar systems using isothermal titration calorimetry. Journal of Thermal Analysis and Calorimetry, 80 (1). pp. 43-47. ISSN 1388-6150 (Print), 1572-8943 (Online) (doi:https://doi.org/10.1007/s10973-005-0611-z)

2D correlation spectroscopy

Sasic, S., Clark, D.A. and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2004) Analysing Raman images of pharmaceutical products by sample-sample 2D correlation spectroscopy. Journal of Pharmacy and Pharmacology, 56 (S1). p. 4. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489186)

4-Vinylpyridine

Seidel, J., Pinkrah, V.T., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Chowdhry, B.Z. and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Isothermal titration calorimetric studies of the acid-base properties of poly (N-isopropylacrylamide-co-4-vinylpyridine) cationic polyelectrolyte colloidal microgels. Thermochimica Acta, 414 (1). pp. 47-52. ISSN 0040-6031 (doi:https://doi.org/10.1016/j.tca.2003.11.012)

acquisition

Day, I.J., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Snowden, M.J. ORCID: 0000-0002-1087-2692 and Davis, A.L. (2008) Investigation of the potential of the dissolution dynamic nuclear polarization method for general sensitivity enhancement in small-molecule NMR spectroscopy. Applied Magnetic Resonance, 34 (3-4). pp. 453-460. ISSN 0937-9347 (Print), 1613-7507 (Online) (doi:https://doi.org/10.1007/s00723-008-0122-8)

amorphous

Major, P.J., Cornelius, V.J., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Murphy, J. (2007) The implementation of FT-Raman spectroscopy to study solid state moisture induced changes in the crystallographic nature of pharmaceutical excipients - a lesson in humidity. Journal of Pharmacy and Pharmacology, 59 (S1). A38-A38. ISSN 0022-3573 (doi:https://doi.org/10.1211/002235707781849999)

antimicrobial properties

Vine, G.J., Chowdhry, B.Z. and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2005) Antimicrobial properties of surface-active agents by flow calorimetry. Journal of Pharmacy and Pharmacology, 57 (S1). S107-S107. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248406)

base catalysed hydrolysis of methyl paraben

O'Neill, M.A.A., Beezer, A.E., Labetoulle, C., Nicolaides, L., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Orchard, J.A., Connor, J.A., Kemp, R.B. and Olomolaiye, D. (2003) The base catalysed hydrolysis of methyl paraben: a test reaction for flow microcalorimeters used for determination of both kinetic and thermodynamic parameters. Thermochimica Acta, 399 (1-2). pp. 63-71. ISSN 0040-6031 (doi:https://doi.org/10.1016/S0040-6031(02)00401-X)

buccal delivery

Ayensu, I., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Boateng, J.S. ORCID: 0000-0002-6310-729X (2010) Novel lyophilization cycle development of chitosan based formulation for buccal delivery using paracetamol as a model drug. The AAPS Journal, 12 (S2). ISSN 1550-7416

calorimetric data

O'Neill, M.A.A., Beezer, A.E., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Orchard, J. and Connor, J.A. (2004) Determination of Michaelis-Menten parameters obtained from isothermal flow calorimetric data. Thermochimica Acta, 417 (2). pp. 187-192. ISSN 0040-6031 (doi:https://doi.org/10.1016/j.tca.2003.07.019)

calorimetry

Mitchard, N.M., Beezer, A.E., Mitchell, J.C., Armstrong, J.K., Chowdhry, B.Z., Leharne, S. and Buckton, G. (1992) Thermodynamic analysis of scanning calorimetric transitions observed for dilute aqueous solutions of ABA block copolymers. Journal of Physical Chemistry, 96 (23). pp. 9507-9512. ISSN 0022-3654 (doi:https://doi.org/10.1021/j100202a079)

catalysis

Morao, I., Higginson, P.D., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) GRIND-based QSPR method to predict the enantiomeric excess in catalysis. Journal of Pharmacy and Pharmacology, 57 (S1). S31-S31. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248343)

catalysts

Dunn, P.J., Hoffmann, W., Kang, Y., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) A comparison of catalysts to promote imidazolide couplings including the identification of 2-hydroxy-5-nitropyridine as a new, safe and effective catalyst. Journal of Pharmacy and Pharmacology, 57 (S1). S32-S33. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248451)

cationic colloidal microgel

chemical modification

Gibson, G.H., Snowden, M.J. ORCID: 0000-0002-1087-2692 and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2004) Chemical modification of the edible film polysaccharide pullulan. Journal of Pharmacy and Pharmacology, 56 (S1). pp. 50-51. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489249)

chirality

Johnson, M.N., Feeder, N., Snowden, M.J. ORCID: 0000-0002-1087-2692 and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2004) Effects of chirality on the salt formation of histidine. Journal of Pharmacy and Pharmacology, 56 (S1). pp. 24-25. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489212)

chitosan

co-polymer

co-polymer microgels

Nur, H., Cornelius, V.J., Benée, L.S., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Day, I.J. and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2009) Semi-quantitative analysis of the monomer composition in co-polymer microgels using solid state Raman and NMR spectroscopy. Analyst, 134 (7). pp. 1366-1372. ISSN 0003-2654 (Print), 1364-5528 (Online) (doi:https://doi.org/10.1039/B816792C)

colloidal microgels

Gracia, L.H., Snowden, M.J. ORCID: 0000-0002-1087-2692 , Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Humphrey, M.J. (2005) The structural and compositional analysis of colloidal microgels and their development as controlled absorption/release devices. Journal of Pharmacy and Pharmacology, 57 (S1). S61-S62. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248460)

Pinkrah, V.T., Snowden, M.J. ORCID: 0000-0002-1087-2692 , Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Seidel, J., Chowdhry, B.Z. and Fern, G.R. (2003) Physicochemical properties of poly(N-isopropylacrylamide-co-4-vinylpyridine) cationic polyelectrolyte colloidal microgels. Langmuir, 19 (3). pp. 585-590. ISSN 0743-7463 (Print), 1520-5827 (Online) (doi:https://doi.org/10.1021/la026283l)

column liquid chromatography

Mathews, B.T., Higginson, P.D., Lyons, R., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Sach, N.W., Snowden, M.J. ORCID: 0000-0002-1087-2692 , Taylor, M.R. and Wright, A.G. (2004) Improving quantitative measurements for the evaporative light scattering detector. Chromatographia, 60 (11-12). pp. 625-633. ISSN 0009-5893 (Print), 1612-1112 (Online) (doi:https://doi.org/10.1365/s10337-004-0441-3)

compositional analysis

correlation

Lansdell-Smith, P.H., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Hyde, R.M. (2005) Correlation of permeability through skin and a model PDMS membrane by computational chemistry. Journal of Pharmacy and Pharmacology, 57 (S1). S97-S97. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248488)

crosslinked pullulan

Gibson, G.H., Auffret, A.D., Humphrey, M.J., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) Synthesis and characterisation of hydrophobically modified and crosslinked pullulan with enhanced viscosity characteristics. Journal of Pharmacy and Pharmacology, 57 (S1). S62-S62. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248460)

crystalline

Cyclodextrin complex

Waters, Laura J., Bedford, Susan, Parkes, Gareth M.B. and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2010) Influence of lipophilicity on drug-cyclodextrin interactions: A calorimetric study. Thermochimica Acta, 511 (1-2). pp. 102-106. ISSN 0040-6031 (doi:https://doi.org/10.1016/j.tca.2010.07.031)

Deformation

Hooper, D., Clarke, F.C., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2016) A modern approach to the Heckel Equation: The effect of compaction pressure on the yield pressure of ibuprofen and its sodium salt. Journal of Nanomedicine and Nanotechnology, 7 (381). p. 2. ISSN 2157-7439 (Online) (doi:https://doi.org/10.4172/2157-7439.1000381)

dendrimers

Beezer, A.E., King, A.S.H., Martin, I.K., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Twyman, L.J. and Wain, C.F. (2003) Dendrimers as potential drug carriers; encapsulation of acidic hydrophobes within water soluble PAMAM derivatives. Tetrahedron, 59 (22). pp. 3873-3880. ISSN 0040-4020 (Online)

detector calibration

dissolution

DLS

Nur, H., Pinkrah, V. T., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Benée, L.S. and Snowden, M. J. ORCID: 0000-0002-1087-2692 (2009) Synthesis and properties of polyelectrolyte microgel particles. Advances in Colloid and Interface Science, 158 (1-2). pp. 15-20. ISSN 0001-8686 (doi:https://doi.org/10.1016/j.cis.2009.07.008)

drug

drug carriers

dynamic nuclear polarization method

edible film

electrophoretic mobility

ELSD

enantiomeric excess

enzymes

ethylene oxide

evaporative light-scattering detector

films

Khan, S., Boateng, J.S. ORCID: 0000-0002-6310-729X , Okeke, O., Trivedi, V. ORCID: 0000-0001-9304-9214 and Mitchell, J.C. ORCID: 0000-0003-2945-3292 (2014) Physico-chemical characterization of oral thin film for paediatric buccal drug delivery. In: APS PharmSci 2014, 8-10 Sep 2014, University of Hertfordshire, Hatfield, UK.

flow calorimetry

fracture toughness

Taylor, L.J., Papadopoulos, D.G., Dunn, P.J., Bentham, A.C., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Mechanical characterisation of powders using nanoindentation. Powder Technology, 143-4. pp. 179-185. ISSN 0032-5910 (doi:https://doi.org/10.1016/j.powtec.2004.04.012)

freeze-dried materials

Fei, D., Auffrett, A.D., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) The study of the reaction between xylose and glycine in freeze-dried materials. Journal of Pharmacy and Pharmacology, 56 (S1). S24-S24. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489212)

freeze-dried wafers

FT-Raman

glycine

Heckel equation

humidity

imidazolide coupling

isothermal

isothermal flow

isothermal microcalorimetry

O'Neill, M.A.A., Beezer, A.E., Deal, R.M., Morris, A.C. ORCID: 0000-0003-2945-3292 , Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Orchard, J.A. and Connor, J.C. (2003) Survey of the effect of fill volume on the values for the enthalpy and rate constant derived from isothermal microcalorimetry: applications of a newly developed test reaction. Thermochimica Acta, 397 (1-2). pp. 163-169. ISSN 0040-6031 (doi:https://doi.org/10.1016/S0040-6031(02)00270-8)

isothermal titration calorimetry

ITC

LC-MS/MS assays

Alfazema, L.N., Richards, D.S., Gelebart, S., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) Achieving high accuracy and precision in LC-MS/MS assays for pharmaceutical analysis. Journal of Pharmacy and Pharmacology, 57 (S1). S47-S47. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248613)

Linear regression

log P

mechanical properties

Taylor, L.J., Papadopoulos, D.G., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Influence of particle size on mechanical properties of pharmaceutical crystals. Journal of Pharmacy and Pharmacology, 56 (S1). p. 37. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489302)

metolose

micellar liquid chromatography

Waters, Laura J., Leharne, S.A., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Hanrahan, J.P. (2007) Determination of micelle/water partition coefficients and associated thermodynamic data for dialkyl phthalate esters. Journal of Thermal Analysis and Calorimetry, 90 (1). pp. 283-288. ISSN 1388-6150 (Print), 1572-8943 (Online) (doi:https://doi.org/10.1007/s10973-006-7792-y)

micellar systems

micelle size

micelles

Michaelis-Menten kinetics

Michaelis-Menten parameters

microgel swelling behavior

Pinkrah, V.T., Beezer, A.E., Chowdry, B.Z., Gracia, L.H., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Thermodynamic considerations of microgel swelling behavior. Langmuir, 20 (20). pp. 8531-8536. ISSN 0743-7463 (Print), 1520-5827 (Online) (doi:https://doi.org/10.1021/la035765+)

microgels

MLC

monomer composition

nanoindentation

Taylor, L.J., Papadopoulos, D.G., Dunn, P.J., Bentham, A.C., Dawson, N.J., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2004) Predictive milling of pharmaceutical materials using nanoindentation of single crystals. Organic Process Research & Development, 8 (4). pp. 674-679. ISSN 1083-6160 (Print), 1520-586X (Online) (doi:https://doi.org/10.1021/op0300241)

NMR spectroscopy

NSAID

oxide block copolymers

paediatric

particle size

Narishetty, S., Humphrey, M.J., Mitchell, J.C. ORCID: 0000-0003-2945-3292 , Papadopoulos, D., Snowden, M.J. ORCID: 0000-0002-1087-2692 and Ticehurst, M.D. (2004) Influence of particle size on surface energy components of inhalation grade lactose. Journal of Pharmacy and Pharmacology, 56 (S1). p. 22. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235704777489212)

partitioning

PDMS membrane

permeability

pH and temperature responsive swelling

pharmaceutical --------------------------------------------------------------------------------

pharmaceutical crystals

pharmaceutical products

phthalate ester

phthalate esters

polyelectrolyte

polysaccharide pullulan

potentiometric titration

powder flow behaviour

Gururajan, B., Bentham, A.C., Mitchell, J.C. ORCID: 0000-0003-2945-3292 and Snowden, M.J. ORCID: 0000-0002-1087-2692 (2005) Mapping powder flow behaviour at different pharmaceutical processing stage. Journal of Pharmacy and Pharmacology, 57 (S1). S66-S66. ISSN 0022-3573 (Print), 2042-7158 (Online) (doi:https://doi.org/10.1211/002235705778248604)

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