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Items where Author is "Everett, Jeremy R."

Items where Author is "Everett, Jeremy R."

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(HTS) 10th Anniversary IDDST Conference 2012 6-hydroxy-6-methyl-heptan-3-one Academic acetaminophen ageing allyl formate bacteria biofluids bioRxiv preprint server biosynthesis C57BL/6J cells chemometrics chemotherapy China classification colorectal cancer diagnosis disease diversity Drug development Drug discovery drug metabolism Drug Metabolism and Disposition ethionine FMO5 KO galactosamine genomics glucuronide HCT116 High throughput screening High Throughput Screening (HTS) HTS humans hypertyrosinemia hypotaurine isoniazid KRAS Lead discovery efficiency liver Magic Angle Spinning medicine meeting highlights metabolic entropy metabolic profiling Metabolite identification metabolite identification carbon efficiency (MICE) metabolite identification efficiency (MIE) metabolites metabolomics metabonomics Metabonomics etabolomics metabotypes Molecular probes Molecular redundancy molecular spectroscopic information Molecular structure MRI MRS mutations Nanjing NMR NMR spectroscopy Nuclear Magnetic Resonance Nuclear magnetic resonance (NMR) spectroscopy Nuclear magnetic resonance spectroscopy Orthogonal-Partial Least Squares p-cresol Pan-assay interference compounds (PAINS) Partial Least Squares pattern recognition personalised health care personalised healthcare personalised medicine Personalised or precision medicine personalized medicine pharmacogenomics pharmacometabolomics pharmacometabonomics plasma plate based precision medicine prediction prognosis rat rule of 40 (Ro40) screening file subset sulfate surgery SW48 systems medicine taurine thioacetamide toxicity tyrosine aminotransferase urine
Number of items: 155.

(HTS)

Bell, Andrew S., Bradley, Joseph, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Knight, Michelle, Loesel, Jens, Mathias, John, McLoughlin, David, Mills, James, Sharp, Robert E., Williams, Christine and Wood, Terence P. (2013) Plate-based diversity subset screening: an efficient paradigm for high throughput screening of a large screening file. Molecular Diversity, 17 (2). pp. 319-335. ISSN 1381-1991 (Print), 1573-501X (Online) (doi:https://doi.org/10.1007/s11030-013-9438-x)

10th Anniversary IDDST Conference

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2013) Report on the 10th Anniversary of International Drug Discovery Science and Technology Conference, 8-10 November 2012, Nanjing, China. Expert Opinion on Drug Discovery, 8 (3). pp. 357-361. ISSN 1746-0441 (Print), 1746-045X (Online) (doi:https://doi.org/10.1517/17460441.2013.762353)

2012

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2013) Report on the 10th Anniversary of International Drug Discovery Science and Technology Conference, 8-10 November 2012, Nanjing, China. Expert Opinion on Drug Discovery, 8 (3). pp. 357-361. ISSN 1746-0441 (Print), 1746-045X (Online) (doi:https://doi.org/10.1517/17460441.2013.762353)

6-hydroxy-6-methyl-heptan-3-one

Scott, Flora H., Varshavi, Dorsa, Veeravalli, Sunil, Phillips, Ian R., Veselkov, Kirill, Strittmatter, Nicole, Takats, Zoltan, Shephard, Elizabeth A. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2018) Metabolic biomarkers of ageing in C57BL/6J wild-type and flavin-containing monooxygenase 5 (FMO5)-knockout mice. Frontiers in Molecular Biosciences, 5:28. ISSN 2296-889X (Online) (doi:https://doi.org/10.3389/fmolb.2018.00028)

Academic

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Academic drug discovery: Current status and prospects. Expert Opinion on Drug Discovery, 10 (9). pp. 937-944. ISSN 1746-0441 (Print), 1746-045X (Online) (doi:https://doi.org/10.1517/17460441.2015.1059816)

acetaminophen

Clayton, T. Andrew, Baker, David, Lindon, John C., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2009) Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 106 (34). pp. 14728-14733. ISSN 0027-8424 (Print), 1091-6490 (Online) (doi:https://doi.org/10.1073/pnas.0904489106)

ageing

Scott, Flora H., Varshavi, Dorsa, Veeravalli, Sunil, Phillips, Ian R., Veselkov, Kirill, Strittmatter, Nicole, Takats, Zoltan, Shephard, Elizabeth A. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2018) Metabolic biomarkers of ageing in C57BL/6J wild-type and flavin-containing monooxygenase 5 (FMO5)-knockout mice. Frontiers in Molecular Biosciences, 5:28. ISSN 2296-889X (Online) (doi:https://doi.org/10.3389/fmolb.2018.00028)

allyl formate

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

bacteria

Clayton, T. Andrew, Baker, David, Lindon, John C., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2009) Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 106 (34). pp. 14728-14733. ISSN 0027-8424 (Print), 1091-6490 (Online) (doi:https://doi.org/10.1073/pnas.0904489106)

biofluids

Lindon, John C., Nicholson, Jeremy K., Holmes, Elaine and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2000) Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids. Concepts in Magnetic Resonance, 12 (5). pp. 289-320. ISSN 1552-5023 (online) (doi:https://doi.org/10.1002/1099-0534(2000)12:5<289::AID-CMR3>3.0.CO;2-W)

bioRxiv preprint server

Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth A. (2020) Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine. Drug Metabolism and Disposition, 48 (4). ISSN 0090-9556 (Print), 1521-009X (Online) (doi:https://doi.org/10.1124/dmd.119.089995)

biosynthesis

Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth A. (2020) Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine. Drug Metabolism and Disposition, 48 (4). ISSN 0090-9556 (Print), 1521-009X (Online) (doi:https://doi.org/10.1124/dmd.119.089995)

C57BL/6J

Scott, Flora H., Varshavi, Dorsa, Veeravalli, Sunil, Phillips, Ian R., Veselkov, Kirill, Strittmatter, Nicole, Takats, Zoltan, Shephard, Elizabeth A. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2018) Metabolic biomarkers of ageing in C57BL/6J wild-type and flavin-containing monooxygenase 5 (FMO5)-knockout mice. Frontiers in Molecular Biosciences, 5:28. ISSN 2296-889X (Online) (doi:https://doi.org/10.3389/fmolb.2018.00028)

cells

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-021-01852-w)

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-020-01674-2)

chemometrics

Lindon, John C., Nicholson, Jeremy K., Holmes, Elaine and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2000) Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids. Concepts in Magnetic Resonance, 12 (5). pp. 289-320. ISSN 1552-5023 (online) (doi:https://doi.org/10.1002/1099-0534(2000)12:5<289::AID-CMR3>3.0.CO;2-W)

chemotherapy

Nicholson, Jeremy K., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Lindon, John C. (2012) Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy. Expert Opinion on Drug Metabolism & Toxicology, 8 (2). pp. 135-139. ISSN 1742-5255 (doi:https://doi.org/10.1517/17425255.2012.646987)

China

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2013) Report on the 10th Anniversary of International Drug Discovery Science and Technology Conference, 8-10 November 2012, Nanjing, China. Expert Opinion on Drug Discovery, 8 (3). pp. 357-361. ISSN 1746-0441 (Print), 1746-045X (Online) (doi:https://doi.org/10.1517/17460441.2013.762353)

classification

Lindon, John C., Nicholson, Jeremy K., Holmes, Elaine and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2000) Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids. Concepts in Magnetic Resonance, 12 (5). pp. 289-320. ISSN 1552-5023 (online) (doi:https://doi.org/10.1002/1099-0534(2000)12:5<289::AID-CMR3>3.0.CO;2-W)

colorectal cancer

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-021-01852-w)

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-020-01674-2)

diagnosis

Nicholson, Jeremy K., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Lindon, John C. (2012) Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy. Expert Opinion on Drug Metabolism & Toxicology, 8 (2). pp. 135-139. ISSN 1742-5255 (doi:https://doi.org/10.1517/17425255.2012.646987)

disease

Lindon, John C., Nicholson, Jeremy K., Holmes, Elaine and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2000) Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids. Concepts in Magnetic Resonance, 12 (5). pp. 289-320. ISSN 1552-5023 (online) (doi:https://doi.org/10.1002/1099-0534(2000)12:5<289::AID-CMR3>3.0.CO;2-W)

diversity

Bell, Andrew S., Bradley, Joseph, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Knight, Michelle, Loesel, Jens, Mathias, John, McLoughlin, David, Mills, James, Sharp, Robert E., Williams, Christine and Wood, Terence P. (2013) Plate-based diversity subset screening: an efficient paradigm for high throughput screening of a large screening file. Molecular Diversity, 17 (2). pp. 319-335. ISSN 1381-1991 (Print), 1573-501X (Online) (doi:https://doi.org/10.1007/s11030-013-9438-x)

Drug development

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Drug discovery and development: the role of NMR. eMagRes. John Wiley & Sons, Ltd., London, UK, pp. 137-150. ISBN 9780470034590 (doi:https://doi.org/10.1002/9780470034590.emrstm1389)

Drug discovery

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Academic drug discovery: Current status and prospects. Expert Opinion on Drug Discovery, 10 (9). pp. 937-944. ISSN 1746-0441 (Print), 1746-045X (Online) (doi:https://doi.org/10.1517/17460441.2015.1059816)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Drug discovery and development: the role of NMR. eMagRes. John Wiley & Sons, Ltd., London, UK, pp. 137-150. ISBN 9780470034590 (doi:https://doi.org/10.1002/9780470034590.emrstm1389)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2013) Report on the 10th Anniversary of International Drug Discovery Science and Technology Conference, 8-10 November 2012, Nanjing, China. Expert Opinion on Drug Discovery, 8 (3). pp. 357-361. ISSN 1746-0441 (Print), 1746-045X (Online) (doi:https://doi.org/10.1517/17460441.2013.762353)

drug metabolism

Nicholson, Jeremy K., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Lindon, John C. (2012) Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy. Expert Opinion on Drug Metabolism & Toxicology, 8 (2). pp. 135-139. ISSN 1742-5255 (doi:https://doi.org/10.1517/17425255.2012.646987)

Drug Metabolism and Disposition

Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth A. (2020) Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine. Drug Metabolism and Disposition, 48 (4). ISSN 0090-9556 (Print), 1521-009X (Online) (doi:https://doi.org/10.1124/dmd.119.089995)

ethionine

Clayton, T. Andrew, Lindon, John C., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Charuel, Claude, Hanton, Gilles, Le Net, Jean-Loic, Provost, Jean-Pierre and Nicholson, Jeremy K. (2006) Hepatotoxin-induced hypertyrosinemia and its toxicological significance. Archives of Toxicology, 81 (3). pp. 201-210. ISSN 0340-5761 (Print), 1432-0738 (Online) (doi:https://doi.org/10.1007/s00204-006-0136-7)

FMO5 KO

Scott, Flora H., Varshavi, Dorsa, Veeravalli, Sunil, Phillips, Ian R., Veselkov, Kirill, Strittmatter, Nicole, Takats, Zoltan, Shephard, Elizabeth A. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2018) Metabolic biomarkers of ageing in C57BL/6J wild-type and flavin-containing monooxygenase 5 (FMO5)-knockout mice. Frontiers in Molecular Biosciences, 5:28. ISSN 2296-889X (Online) (doi:https://doi.org/10.3389/fmolb.2018.00028)

galactosamine

Clayton, T. Andrew, Lindon, John C., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Charuel, Claude, Hanton, Gilles, Le Net, Jean-Loic, Provost, Jean-Pierre and Nicholson, Jeremy K. (2006) Hepatotoxin-induced hypertyrosinemia and its toxicological significance. Archives of Toxicology, 81 (3). pp. 201-210. ISSN 0340-5761 (Print), 1432-0738 (Online) (doi:https://doi.org/10.1007/s00204-006-0136-7)

genomics

Nicholson, Jeremy K., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Lindon, John C. (2012) Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy. Expert Opinion on Drug Metabolism & Toxicology, 8 (2). pp. 135-139. ISSN 1742-5255 (doi:https://doi.org/10.1517/17425255.2012.646987)

glucuronide

Clayton, T. Andrew, Baker, David, Lindon, John C., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2009) Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 106 (34). pp. 14728-14733. ISSN 0027-8424 (Print), 1091-6490 (Online) (doi:https://doi.org/10.1073/pnas.0904489106)

HCT116

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-021-01852-w)

High throughput screening

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Academic drug discovery: Current status and prospects. Expert Opinion on Drug Discovery, 10 (9). pp. 937-944. ISSN 1746-0441 (Print), 1746-045X (Online) (doi:https://doi.org/10.1517/17460441.2015.1059816)

Bell, Andrew S., Bradley, Joseph, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Knight, Michelle, Loesel, Jens, Mathias, John, McLoughlin, David, Mills, James, Sharp, Robert E., Williams, Christine and Wood, Terence P. (2013) Plate-based diversity subset screening: an efficient paradigm for high throughput screening of a large screening file. Molecular Diversity, 17 (2). pp. 319-335. ISSN 1381-1991 (Print), 1573-501X (Online) (doi:https://doi.org/10.1007/s11030-013-9438-x)

High Throughput Screening (HTS)

Bakken, Gregory A., Bell, Andrew S., Boehm, Markus, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Gonzales, Rosalia, Hepworth, David, Klug-McLeod, Jacquelyn L., Lanfear, Jeremy, Loesel, Jens, Mathias, John and Wood, Terence P. (2012) Shaping a screening file for maximal lead discovery efficiency and effectiveness: elimination of molecular redundancy. Journal of Chemical Information and Modeling, 52 (11). pp. 2937-2949. ISSN 1549-9596 (Print), 1549-960X (Online) (doi:https://doi.org/10.1021/ci300372a)

HTS

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Academic drug discovery: Current status and prospects. Expert Opinion on Drug Discovery, 10 (9). pp. 937-944. ISSN 1746-0441 (Print), 1746-045X (Online) (doi:https://doi.org/10.1517/17460441.2015.1059816)

humans

Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth A. (2020) Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine. Drug Metabolism and Disposition, 48 (4). ISSN 0090-9556 (Print), 1521-009X (Online) (doi:https://doi.org/10.1124/dmd.119.089995)

hypertyrosinemia

Clayton, T. Andrew, Lindon, John C., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Charuel, Claude, Hanton, Gilles, Le Net, Jean-Loic, Provost, Jean-Pierre and Nicholson, Jeremy K. (2006) Hepatotoxin-induced hypertyrosinemia and its toxicological significance. Archives of Toxicology, 81 (3). pp. 201-210. ISSN 0340-5761 (Print), 1432-0738 (Online) (doi:https://doi.org/10.1007/s00204-006-0136-7)

hypotaurine

Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth A. (2020) Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine. Drug Metabolism and Disposition, 48 (4). ISSN 0090-9556 (Print), 1521-009X (Online) (doi:https://doi.org/10.1124/dmd.119.089995)

isoniazid

Clayton, T. Andrew, Lindon, John C., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Charuel, Claude, Hanton, Gilles, Le Net, Jean-Loic, Provost, Jean-Pierre and Nicholson, Jeremy K. (2006) Hepatotoxin-induced hypertyrosinemia and its toxicological significance. Archives of Toxicology, 81 (3). pp. 201-210. ISSN 0340-5761 (Print), 1432-0738 (Online) (doi:https://doi.org/10.1007/s00204-006-0136-7)

KRAS

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-021-01852-w)

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-020-01674-2)

Lead discovery efficiency

Bakken, Gregory A., Bell, Andrew S., Boehm, Markus, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Gonzales, Rosalia, Hepworth, David, Klug-McLeod, Jacquelyn L., Lanfear, Jeremy, Loesel, Jens, Mathias, John and Wood, Terence P. (2012) Shaping a screening file for maximal lead discovery efficiency and effectiveness: elimination of molecular redundancy. Journal of Chemical Information and Modeling, 52 (11). pp. 2937-2949. ISSN 1549-9596 (Print), 1549-960X (Online) (doi:https://doi.org/10.1021/ci300372a)

liver

Clayton, T. Andrew, Lindon, John C., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Charuel, Claude, Hanton, Gilles, Le Net, Jean-Loic, Provost, Jean-Pierre and Nicholson, Jeremy K. (2006) Hepatotoxin-induced hypertyrosinemia and its toxicological significance. Archives of Toxicology, 81 (3). pp. 201-210. ISSN 0340-5761 (Print), 1432-0738 (Online) (doi:https://doi.org/10.1007/s00204-006-0136-7)

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

Magic Angle Spinning

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

medicine

Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth A. (2020) Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine. Drug Metabolism and Disposition, 48 (4). ISSN 0090-9556 (Print), 1521-009X (Online) (doi:https://doi.org/10.1124/dmd.119.089995)

meeting highlights

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2013) Report on the 10th Anniversary of International Drug Discovery Science and Technology Conference, 8-10 November 2012, Nanjing, China. Expert Opinion on Drug Discovery, 8 (3). pp. 357-361. ISSN 1746-0441 (Print), 1746-045X (Online) (doi:https://doi.org/10.1517/17460441.2013.762353)

metabolic entropy

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Holmes, Elaine, Veselkov, Kirill A., Lindon, John C. and Nicholson, Jeremy K. (2019) A unified conceptual framework for metabolic phenotyping in diagnosis and prognosis. Trends in Pharmacological Sciences, 40 (10). pp. 763-773. ISSN 0165-6147 (Print), 1873-3735 (Online) (doi:https://doi.org/10.1016/j.tips.2019.08.004)

metabolic profiling

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-021-01852-w)

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-020-01674-2)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2017) NMR-based pharmacometabonomics: A new paradigm for personalised or precision medicine. Progress in Nuclear Magnetic Resonance Spectroscopy, 102-3. pp. 1-14. ISSN 0079-6565 (Print), 1873-3301 (Online) (doi:https://doi.org/10.1016/j.pnmrs.2017.04.003)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2016) From metabonomics to pharmacometabonomics: The role of metabolic profiling in personalized medicine. Frontiers in Pharmacology, 7:297. ISSN 1663-9812 (doi:https://doi.org/10.3389/fphar.2016.00297)

Metabolite identification

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Dona, Anthony C., Kyriakides, Michael, Scott, Flora, Shephard, Elizabeth A., Varshavi, Dorsa and Veselkov, Kirill (2016) A guide to the identification of metabolites in NMR-based metabonomics/metabolomics experiments. Computational and Structural Biotechnology Journal, 14. pp. 135-153. ISSN 2001-0370 (Print), 2001-0370 (Online) (doi:https://doi.org/10.1016/j.csbj.2016.02.005)

metabolite identification carbon efficiency (MICE)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) A new paradigm for known metabolite identification in metabonomics/metabolomics: Metabolite identification efficiency. Computational and Structural Biotechnology Journal, 13. pp. 131-144. ISSN 2001-0370 (doi:https://doi.org/10.1016/j.csbj.2015.01.002)

metabolite identification efficiency (MIE)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) A new paradigm for known metabolite identification in metabonomics/metabolomics: Metabolite identification efficiency. Computational and Structural Biotechnology Journal, 13. pp. 131-144. ISSN 2001-0370 (doi:https://doi.org/10.1016/j.csbj.2015.01.002)

metabolites

Lindon, John C., Nicholson, Jeremy K., Holmes, Elaine and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2000) Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids. Concepts in Magnetic Resonance, 12 (5). pp. 289-320. ISSN 1552-5023 (online) (doi:https://doi.org/10.1002/1099-0534(2000)12:5<289::AID-CMR3>3.0.CO;2-W)

metabolomics

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-021-01852-w)

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-020-01674-2)

Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth A. (2020) Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine. Drug Metabolism and Disposition, 48 (4). ISSN 0090-9556 (Print), 1521-009X (Online) (doi:https://doi.org/10.1124/dmd.119.089995)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Holmes, Elaine, Veselkov, Kirill A., Lindon, John C. and Nicholson, Jeremy K. (2019) A unified conceptual framework for metabolic phenotyping in diagnosis and prognosis. Trends in Pharmacological Sciences, 40 (10). pp. 763-773. ISSN 0165-6147 (Print), 1873-3735 (Online) (doi:https://doi.org/10.1016/j.tips.2019.08.004)

Scott, Flora H., Varshavi, Dorsa, Veeravalli, Sunil, Phillips, Ian R., Veselkov, Kirill, Strittmatter, Nicole, Takats, Zoltan, Shephard, Elizabeth A. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2018) Metabolic biomarkers of ageing in C57BL/6J wild-type and flavin-containing monooxygenase 5 (FMO5)-knockout mice. Frontiers in Molecular Biosciences, 5:28. ISSN 2296-889X (Online) (doi:https://doi.org/10.3389/fmolb.2018.00028)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2016) From metabonomics to pharmacometabonomics: The role of metabolic profiling in personalized medicine. Frontiers in Pharmacology, 7:297. ISSN 1663-9812 (doi:https://doi.org/10.3389/fphar.2016.00297)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Pharmacometabonomics in humans: a new tool for personalized medicine. Pharmacogenomics, 16 (7). pp. 737-754. ISSN 1462-2416 (doi:https://doi.org/10.2217/PGS.15.20)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) A new paradigm for known metabolite identification in metabonomics/metabolomics: Metabolite identification efficiency. Computational and Structural Biotechnology Journal, 13. pp. 131-144. ISSN 2001-0370 (doi:https://doi.org/10.1016/j.csbj.2015.01.002)

Nicholson, Jeremy K., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Lindon, John C. (2012) Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy. Expert Opinion on Drug Metabolism & Toxicology, 8 (2). pp. 135-139. ISSN 1742-5255 (doi:https://doi.org/10.1517/17425255.2012.646987)

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

metabonomics

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-021-01852-w)

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-020-01674-2)

Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth A. (2020) Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine. Drug Metabolism and Disposition, 48 (4). ISSN 0090-9556 (Print), 1521-009X (Online) (doi:https://doi.org/10.1124/dmd.119.089995)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Holmes, Elaine, Veselkov, Kirill A., Lindon, John C. and Nicholson, Jeremy K. (2019) A unified conceptual framework for metabolic phenotyping in diagnosis and prognosis. Trends in Pharmacological Sciences, 40 (10). pp. 763-773. ISSN 0165-6147 (Print), 1873-3735 (Online) (doi:https://doi.org/10.1016/j.tips.2019.08.004)

Scott, Flora H., Varshavi, Dorsa, Veeravalli, Sunil, Phillips, Ian R., Veselkov, Kirill, Strittmatter, Nicole, Takats, Zoltan, Shephard, Elizabeth A. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2018) Metabolic biomarkers of ageing in C57BL/6J wild-type and flavin-containing monooxygenase 5 (FMO5)-knockout mice. Frontiers in Molecular Biosciences, 5:28. ISSN 2296-889X (Online) (doi:https://doi.org/10.3389/fmolb.2018.00028)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2017) NMR-based pharmacometabonomics: A new paradigm for personalised or precision medicine. Progress in Nuclear Magnetic Resonance Spectroscopy, 102-3. pp. 1-14. ISSN 0079-6565 (Print), 1873-3301 (Online) (doi:https://doi.org/10.1016/j.pnmrs.2017.04.003)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2016) From metabonomics to pharmacometabonomics: The role of metabolic profiling in personalized medicine. Frontiers in Pharmacology, 7:297. ISSN 1663-9812 (doi:https://doi.org/10.3389/fphar.2016.00297)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Pharmacometabonomics in humans: a new tool for personalized medicine. Pharmacogenomics, 16 (7). pp. 737-754. ISSN 1462-2416 (doi:https://doi.org/10.2217/PGS.15.20)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Drug discovery and development: the role of NMR. eMagRes. John Wiley & Sons, Ltd., London, UK, pp. 137-150. ISBN 9780470034590 (doi:https://doi.org/10.1002/9780470034590.emrstm1389)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) A new paradigm for known metabolite identification in metabonomics/metabolomics: Metabolite identification efficiency. Computational and Structural Biotechnology Journal, 13. pp. 131-144. ISSN 2001-0370 (doi:https://doi.org/10.1016/j.csbj.2015.01.002)

Cunningham, Katharine, Claus, Sandrine P., Lindon, John C., Holmes, Elaine, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Nicholson, Jeremy K. and Coen, Muireann (2012) Pharmacometabonomic characterization of xenobiotic and endogenous metabolic phenotypes that account for inter-individual variation in isoniazid-induced toxicological response. Journal of Proteome Research, 11 (9). pp. 4630-4642. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr300430u)

Nicholson, Jeremy K., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Lindon, John C. (2012) Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy. Expert Opinion on Drug Metabolism & Toxicology, 8 (2). pp. 135-139. ISSN 1742-5255 (doi:https://doi.org/10.1517/17425255.2012.646987)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2006) Metabolic applications in clinical pharmaceutical R&D. In: Lindon, John C., Nicholson, Jeremy K. and Holmes, Elaine, (eds.) The Handbook of Metabonomics and Metabolomics. Elsevier, Amsterdam, The Netherlands, pp. 279-287. ISBN 9780444528414

Clayton, T. Andrew, Lindon, John C., Cloarec, Olivier, Antti, Henrik, Charuel, Claude, Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loïc, Baker, David, Walley, Rosalind J., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2006) Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature, 440 (7087). pp. 1073-1077. ISSN 0028-0836 (Print), 1476-4687 (Online) (doi:https://doi.org/10.1038/nature04648)

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

Lindon, John C., Nicholson, Jeremy K., Holmes, Elaine and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2000) Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids. Concepts in Magnetic Resonance, 12 (5). pp. 289-320. ISSN 1552-5023 (online) (doi:https://doi.org/10.1002/1099-0534(2000)12:5<289::AID-CMR3>3.0.CO;2-W)

Metabonomics etabolomics

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Dona, Anthony C., Kyriakides, Michael, Scott, Flora, Shephard, Elizabeth A., Varshavi, Dorsa and Veselkov, Kirill (2016) A guide to the identification of metabolites in NMR-based metabonomics/metabolomics experiments. Computational and Structural Biotechnology Journal, 14. pp. 135-153. ISSN 2001-0370 (Print), 2001-0370 (Online) (doi:https://doi.org/10.1016/j.csbj.2016.02.005)

metabotypes

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Holmes, Elaine, Veselkov, Kirill A., Lindon, John C. and Nicholson, Jeremy K. (2019) A unified conceptual framework for metabolic phenotyping in diagnosis and prognosis. Trends in Pharmacological Sciences, 40 (10). pp. 763-773. ISSN 0165-6147 (Print), 1873-3735 (Online) (doi:https://doi.org/10.1016/j.tips.2019.08.004)

Molecular probes

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Academic drug discovery: Current status and prospects. Expert Opinion on Drug Discovery, 10 (9). pp. 937-944. ISSN 1746-0441 (Print), 1746-045X (Online) (doi:https://doi.org/10.1517/17460441.2015.1059816)

Molecular redundancy

Bakken, Gregory A., Bell, Andrew S., Boehm, Markus, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Gonzales, Rosalia, Hepworth, David, Klug-McLeod, Jacquelyn L., Lanfear, Jeremy, Loesel, Jens, Mathias, John and Wood, Terence P. (2012) Shaping a screening file for maximal lead discovery efficiency and effectiveness: elimination of molecular redundancy. Journal of Chemical Information and Modeling, 52 (11). pp. 2937-2949. ISSN 1549-9596 (Print), 1549-960X (Online) (doi:https://doi.org/10.1021/ci300372a)

molecular spectroscopic information

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) A new paradigm for known metabolite identification in metabonomics/metabolomics: Metabolite identification efficiency. Computational and Structural Biotechnology Journal, 13. pp. 131-144. ISSN 2001-0370 (doi:https://doi.org/10.1016/j.csbj.2015.01.002)

Molecular structure

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Dona, Anthony C., Kyriakides, Michael, Scott, Flora, Shephard, Elizabeth A., Varshavi, Dorsa and Veselkov, Kirill (2016) A guide to the identification of metabolites in NMR-based metabonomics/metabolomics experiments. Computational and Structural Biotechnology Journal, 14. pp. 135-153. ISSN 2001-0370 (Print), 2001-0370 (Online) (doi:https://doi.org/10.1016/j.csbj.2016.02.005)

MRI

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Drug discovery and development: the role of NMR. eMagRes. John Wiley & Sons, Ltd., London, UK, pp. 137-150. ISBN 9780470034590 (doi:https://doi.org/10.1002/9780470034590.emrstm1389)

MRS

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Drug discovery and development: the role of NMR. eMagRes. John Wiley & Sons, Ltd., London, UK, pp. 137-150. ISBN 9780470034590 (doi:https://doi.org/10.1002/9780470034590.emrstm1389)

mutations

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-021-01852-w)

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-020-01674-2)

Nanjing

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2013) Report on the 10th Anniversary of International Drug Discovery Science and Technology Conference, 8-10 November 2012, Nanjing, China. Expert Opinion on Drug Discovery, 8 (3). pp. 357-361. ISSN 1746-0441 (Print), 1746-045X (Online) (doi:https://doi.org/10.1517/17460441.2013.762353)

NMR

Varshavi, Dorna, Varshavi, Dorsa, McCarthy, Nicola, Veselkov, Kirill, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2021) Metabonomics study of the effects of single copy mutant KRAS in the presence or absence of WT allele using human HCT116 isogenic cell lines. Metabolomics, 17 (12):104. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-021-01852-w)

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-020-01674-2)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Drug discovery and development: the role of NMR. eMagRes. John Wiley & Sons, Ltd., London, UK, pp. 137-150. ISBN 9780470034590 (doi:https://doi.org/10.1002/9780470034590.emrstm1389)

NMR spectroscopy

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2017) NMR-based pharmacometabonomics: A new paradigm for personalised or precision medicine. Progress in Nuclear Magnetic Resonance Spectroscopy, 102-3. pp. 1-14. ISSN 0079-6565 (Print), 1873-3301 (Online) (doi:https://doi.org/10.1016/j.pnmrs.2017.04.003)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Pharmacometabonomics in humans: a new tool for personalized medicine. Pharmacogenomics, 16 (7). pp. 737-754. ISSN 1462-2416 (doi:https://doi.org/10.2217/PGS.15.20)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) A new paradigm for known metabolite identification in metabonomics/metabolomics: Metabolite identification efficiency. Computational and Structural Biotechnology Journal, 13. pp. 131-144. ISSN 2001-0370 (doi:https://doi.org/10.1016/j.csbj.2015.01.002)

Cunningham, Katharine, Claus, Sandrine P., Lindon, John C., Holmes, Elaine, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Nicholson, Jeremy K. and Coen, Muireann (2012) Pharmacometabonomic characterization of xenobiotic and endogenous metabolic phenotypes that account for inter-individual variation in isoniazid-induced toxicological response. Journal of Proteome Research, 11 (9). pp. 4630-4642. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr300430u)

Clayton, T. Andrew, Lindon, John C., Cloarec, Olivier, Antti, Henrik, Charuel, Claude, Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loïc, Baker, David, Walley, Rosalind J., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2006) Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature, 440 (7087). pp. 1073-1077. ISSN 0028-0836 (Print), 1476-4687 (Online) (doi:https://doi.org/10.1038/nature04648)

Lindon, John C., Nicholson, Jeremy K., Holmes, Elaine and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2000) Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids. Concepts in Magnetic Resonance, 12 (5). pp. 289-320. ISSN 1552-5023 (online) (doi:https://doi.org/10.1002/1099-0534(2000)12:5<289::AID-CMR3>3.0.CO;2-W)

Nuclear Magnetic Resonance

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

Nuclear magnetic resonance (NMR) spectroscopy

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Dona, Anthony C., Kyriakides, Michael, Scott, Flora, Shephard, Elizabeth A., Varshavi, Dorsa and Veselkov, Kirill (2016) A guide to the identification of metabolites in NMR-based metabonomics/metabolomics experiments. Computational and Structural Biotechnology Journal, 14. pp. 135-153. ISSN 2001-0370 (Print), 2001-0370 (Online) (doi:https://doi.org/10.1016/j.csbj.2016.02.005)

Nuclear magnetic resonance spectroscopy

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Drug discovery and development: the role of NMR. eMagRes. John Wiley & Sons, Ltd., London, UK, pp. 137-150. ISBN 9780470034590 (doi:https://doi.org/10.1002/9780470034590.emrstm1389)

Orthogonal-Partial Least Squares

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

p-cresol

Clayton, T. Andrew, Baker, David, Lindon, John C., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2009) Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 106 (34). pp. 14728-14733. ISSN 0027-8424 (Print), 1091-6490 (Online) (doi:https://doi.org/10.1073/pnas.0904489106)

Pan-assay interference compounds (PAINS)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Academic drug discovery: Current status and prospects. Expert Opinion on Drug Discovery, 10 (9). pp. 937-944. ISSN 1746-0441 (Print), 1746-045X (Online) (doi:https://doi.org/10.1517/17460441.2015.1059816)

Partial Least Squares

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

pattern recognition

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

Lindon, John C., Nicholson, Jeremy K., Holmes, Elaine and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2000) Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids. Concepts in Magnetic Resonance, 12 (5). pp. 289-320. ISSN 1552-5023 (online) (doi:https://doi.org/10.1002/1099-0534(2000)12:5<289::AID-CMR3>3.0.CO;2-W)

personalised health care

Nicholson, Jeremy K., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Lindon, John C. (2012) Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy. Expert Opinion on Drug Metabolism & Toxicology, 8 (2). pp. 135-139. ISSN 1742-5255 (doi:https://doi.org/10.1517/17425255.2012.646987)

personalised healthcare

Clayton, T. Andrew, Lindon, John C., Cloarec, Olivier, Antti, Henrik, Charuel, Claude, Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loïc, Baker, David, Walley, Rosalind J., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2006) Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature, 440 (7087). pp. 1073-1077. ISSN 0028-0836 (Print), 1476-4687 (Online) (doi:https://doi.org/10.1038/nature04648)

personalised medicine

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Holmes, Elaine, Veselkov, Kirill A., Lindon, John C. and Nicholson, Jeremy K. (2019) A unified conceptual framework for metabolic phenotyping in diagnosis and prognosis. Trends in Pharmacological Sciences, 40 (10). pp. 763-773. ISSN 0165-6147 (Print), 1873-3735 (Online) (doi:https://doi.org/10.1016/j.tips.2019.08.004)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2016) From metabonomics to pharmacometabonomics: The role of metabolic profiling in personalized medicine. Frontiers in Pharmacology, 7:297. ISSN 1663-9812 (doi:https://doi.org/10.3389/fphar.2016.00297)

Personalised or precision medicine

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2017) NMR-based pharmacometabonomics: A new paradigm for personalised or precision medicine. Progress in Nuclear Magnetic Resonance Spectroscopy, 102-3. pp. 1-14. ISSN 0079-6565 (Print), 1873-3301 (Online) (doi:https://doi.org/10.1016/j.pnmrs.2017.04.003)

personalized medicine

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Pharmacometabonomics in humans: a new tool for personalized medicine. Pharmacogenomics, 16 (7). pp. 737-754. ISSN 1462-2416 (doi:https://doi.org/10.2217/PGS.15.20)

pharmacogenomics

Nicholson, Jeremy K., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Lindon, John C. (2012) Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy. Expert Opinion on Drug Metabolism & Toxicology, 8 (2). pp. 135-139. ISSN 1742-5255 (doi:https://doi.org/10.1517/17425255.2012.646987)

pharmacometabolomics

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2016) From metabonomics to pharmacometabonomics: The role of metabolic profiling in personalized medicine. Frontiers in Pharmacology, 7:297. ISSN 1663-9812 (doi:https://doi.org/10.3389/fphar.2016.00297)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Pharmacometabonomics in humans: a new tool for personalized medicine. Pharmacogenomics, 16 (7). pp. 737-754. ISSN 1462-2416 (doi:https://doi.org/10.2217/PGS.15.20)

pharmacometabonomics

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Holmes, Elaine, Veselkov, Kirill A., Lindon, John C. and Nicholson, Jeremy K. (2019) A unified conceptual framework for metabolic phenotyping in diagnosis and prognosis. Trends in Pharmacological Sciences, 40 (10). pp. 763-773. ISSN 0165-6147 (Print), 1873-3735 (Online) (doi:https://doi.org/10.1016/j.tips.2019.08.004)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2017) NMR-based pharmacometabonomics: A new paradigm for personalised or precision medicine. Progress in Nuclear Magnetic Resonance Spectroscopy, 102-3. pp. 1-14. ISSN 0079-6565 (Print), 1873-3301 (Online) (doi:https://doi.org/10.1016/j.pnmrs.2017.04.003)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2016) From metabonomics to pharmacometabonomics: The role of metabolic profiling in personalized medicine. Frontiers in Pharmacology, 7:297. ISSN 1663-9812 (doi:https://doi.org/10.3389/fphar.2016.00297)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Pharmacometabonomics in humans: a new tool for personalized medicine. Pharmacogenomics, 16 (7). pp. 737-754. ISSN 1462-2416 (doi:https://doi.org/10.2217/PGS.15.20)

Cunningham, Katharine, Claus, Sandrine P., Lindon, John C., Holmes, Elaine, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Nicholson, Jeremy K. and Coen, Muireann (2012) Pharmacometabonomic characterization of xenobiotic and endogenous metabolic phenotypes that account for inter-individual variation in isoniazid-induced toxicological response. Journal of Proteome Research, 11 (9). pp. 4630-4642. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr300430u)

Nicholson, Jeremy K., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Lindon, John C. (2012) Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy. Expert Opinion on Drug Metabolism & Toxicology, 8 (2). pp. 135-139. ISSN 1742-5255 (doi:https://doi.org/10.1517/17425255.2012.646987)

Clayton, T. Andrew, Lindon, John C., Cloarec, Olivier, Antti, Henrik, Charuel, Claude, Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loïc, Baker, David, Walley, Rosalind J., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2006) Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature, 440 (7087). pp. 1073-1077. ISSN 0028-0836 (Print), 1476-4687 (Online) (doi:https://doi.org/10.1038/nature04648)

plasma

Scott, Flora H., Varshavi, Dorsa, Veeravalli, Sunil, Phillips, Ian R., Veselkov, Kirill, Strittmatter, Nicole, Takats, Zoltan, Shephard, Elizabeth A. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2018) Metabolic biomarkers of ageing in C57BL/6J wild-type and flavin-containing monooxygenase 5 (FMO5)-knockout mice. Frontiers in Molecular Biosciences, 5:28. ISSN 2296-889X (Online) (doi:https://doi.org/10.3389/fmolb.2018.00028)

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

plate based

Bell, Andrew S., Bradley, Joseph, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Knight, Michelle, Loesel, Jens, Mathias, John, McLoughlin, David, Mills, James, Sharp, Robert E., Williams, Christine and Wood, Terence P. (2013) Plate-based diversity subset screening: an efficient paradigm for high throughput screening of a large screening file. Molecular Diversity, 17 (2). pp. 319-335. ISSN 1381-1991 (Print), 1573-501X (Online) (doi:https://doi.org/10.1007/s11030-013-9438-x)

precision medicine

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Holmes, Elaine, Veselkov, Kirill A., Lindon, John C. and Nicholson, Jeremy K. (2019) A unified conceptual framework for metabolic phenotyping in diagnosis and prognosis. Trends in Pharmacological Sciences, 40 (10). pp. 763-773. ISSN 0165-6147 (Print), 1873-3735 (Online) (doi:https://doi.org/10.1016/j.tips.2019.08.004)

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2015) Pharmacometabonomics in humans: a new tool for personalized medicine. Pharmacogenomics, 16 (7). pp. 737-754. ISSN 1462-2416 (doi:https://doi.org/10.2217/PGS.15.20)

prediction

Clayton, T. Andrew, Lindon, John C., Cloarec, Olivier, Antti, Henrik, Charuel, Claude, Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loïc, Baker, David, Walley, Rosalind J., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2006) Pharmaco-metabonomic phenotyping and personalized drug treatment. Nature, 440 (7087). pp. 1073-1077. ISSN 0028-0836 (Print), 1476-4687 (Online) (doi:https://doi.org/10.1038/nature04648)

prognosis

Nicholson, Jeremy K., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Lindon, John C. (2012) Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy. Expert Opinion on Drug Metabolism & Toxicology, 8 (2). pp. 135-139. ISSN 1742-5255 (doi:https://doi.org/10.1517/17425255.2012.646987)

rat

Clayton, T. Andrew, Lindon, John C., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Charuel, Claude, Hanton, Gilles, Le Net, Jean-Loic, Provost, Jean-Pierre and Nicholson, Jeremy K. (2006) Hepatotoxin-induced hypertyrosinemia and its toxicological significance. Archives of Toxicology, 81 (3). pp. 201-210. ISSN 0340-5761 (Print), 1432-0738 (Online) (doi:https://doi.org/10.1007/s00204-006-0136-7)

rule of 40 (Ro40)

Bell, Andrew S., Bradley, Joseph, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Knight, Michelle, Loesel, Jens, Mathias, John, McLoughlin, David, Mills, James, Sharp, Robert E., Williams, Christine and Wood, Terence P. (2013) Plate-based diversity subset screening: an efficient paradigm for high throughput screening of a large screening file. Molecular Diversity, 17 (2). pp. 319-335. ISSN 1381-1991 (Print), 1573-501X (Online) (doi:https://doi.org/10.1007/s11030-013-9438-x)

screening file

Bell, Andrew S., Bradley, Joseph, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Knight, Michelle, Loesel, Jens, Mathias, John, McLoughlin, David, Mills, James, Sharp, Robert E., Williams, Christine and Wood, Terence P. (2013) Plate-based diversity subset screening: an efficient paradigm for high throughput screening of a large screening file. Molecular Diversity, 17 (2). pp. 319-335. ISSN 1381-1991 (Print), 1573-501X (Online) (doi:https://doi.org/10.1007/s11030-013-9438-x)

Bakken, Gregory A., Bell, Andrew S., Boehm, Markus, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Gonzales, Rosalia, Hepworth, David, Klug-McLeod, Jacquelyn L., Lanfear, Jeremy, Loesel, Jens, Mathias, John and Wood, Terence P. (2012) Shaping a screening file for maximal lead discovery efficiency and effectiveness: elimination of molecular redundancy. Journal of Chemical Information and Modeling, 52 (11). pp. 2937-2949. ISSN 1549-9596 (Print), 1549-960X (Online) (doi:https://doi.org/10.1021/ci300372a)

subset

Bell, Andrew S., Bradley, Joseph, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Knight, Michelle, Loesel, Jens, Mathias, John, McLoughlin, David, Mills, James, Sharp, Robert E., Williams, Christine and Wood, Terence P. (2013) Plate-based diversity subset screening: an efficient paradigm for high throughput screening of a large screening file. Molecular Diversity, 17 (2). pp. 319-335. ISSN 1381-1991 (Print), 1573-501X (Online) (doi:https://doi.org/10.1007/s11030-013-9438-x)

sulfate

Clayton, T. Andrew, Baker, David, Lindon, John C., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Nicholson, Jeremy K. (2009) Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism. Proceedings of the National Academy of Sciences of the United States of America (PNAS), 106 (34). pp. 14728-14733. ISSN 0027-8424 (Print), 1091-6490 (Online) (doi:https://doi.org/10.1073/pnas.0904489106)

surgery

Nicholson, Jeremy K., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Lindon, John C. (2012) Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy. Expert Opinion on Drug Metabolism & Toxicology, 8 (2). pp. 135-139. ISSN 1742-5255 (doi:https://doi.org/10.1517/17425255.2012.646987)

SW48

Varshavi, Dorna, Varshavi, Dorsa, Veselkov, Kirill, McCarthy, Nicola, Keun, Hector C. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2020) Metabolic characterization of colorectal cancer cells harbouring different KRAS mutations in codon 12, 13, 61 and 146 using human SW48 isogenic cell lines. Metabolomics, 16 (4):51. ISSN 1573-3882 (Print), 1573-3890 (Online) (doi:https://doi.org/10.1007/s11306-020-01674-2)

systems medicine

Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Holmes, Elaine, Veselkov, Kirill A., Lindon, John C. and Nicholson, Jeremy K. (2019) A unified conceptual framework for metabolic phenotyping in diagnosis and prognosis. Trends in Pharmacological Sciences, 40 (10). pp. 763-773. ISSN 0165-6147 (Print), 1873-3735 (Online) (doi:https://doi.org/10.1016/j.tips.2019.08.004)

taurine

Veeravalli, Sunil, Phillips, Ian R., Freire, Rafael T., Varshavi, Dorsa, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Shephard, Elizabeth A. (2020) Flavin-Containing Monooxygenase 1 (FMO1) catalyzes the production of taurine from hypotaurine. Drug Metabolism and Disposition, 48 (4). ISSN 0090-9556 (Print), 1521-009X (Online) (doi:https://doi.org/10.1124/dmd.119.089995)

thioacetamide

Clayton, T. Andrew, Lindon, John C., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Charuel, Claude, Hanton, Gilles, Le Net, Jean-Loic, Provost, Jean-Pierre and Nicholson, Jeremy K. (2006) Hepatotoxin-induced hypertyrosinemia and its toxicological significance. Archives of Toxicology, 81 (3). pp. 201-210. ISSN 0340-5761 (Print), 1432-0738 (Online) (doi:https://doi.org/10.1007/s00204-006-0136-7)

toxicity

Nicholson, Jeremy K., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 and Lindon, John C. (2012) Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy. Expert Opinion on Drug Metabolism & Toxicology, 8 (2). pp. 135-139. ISSN 1742-5255 (doi:https://doi.org/10.1517/17425255.2012.646987)

Lindon, John C., Nicholson, Jeremy K., Holmes, Elaine and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2000) Metabonomics: metabolic processes studied by NMR spectroscopy of biofluids. Concepts in Magnetic Resonance, 12 (5). pp. 289-320. ISSN 1552-5023 (online) (doi:https://doi.org/10.1002/1099-0534(2000)12:5<289::AID-CMR3>3.0.CO;2-W)

tyrosine aminotransferase

Clayton, T. Andrew, Lindon, John C., Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Charuel, Claude, Hanton, Gilles, Le Net, Jean-Loic, Provost, Jean-Pierre and Nicholson, Jeremy K. (2006) Hepatotoxin-induced hypertyrosinemia and its toxicological significance. Archives of Toxicology, 81 (3). pp. 201-210. ISSN 0340-5761 (Print), 1432-0738 (Online) (doi:https://doi.org/10.1007/s00204-006-0136-7)

urine

Scott, Flora H., Varshavi, Dorsa, Veeravalli, Sunil, Phillips, Ian R., Veselkov, Kirill, Strittmatter, Nicole, Takats, Zoltan, Shephard, Elizabeth A. and Everett, Jeremy R. ORCID: 0000-0003-1550-4482 (2018) Metabolic biomarkers of ageing in C57BL/6J wild-type and flavin-containing monooxygenase 5 (FMO5)-knockout mice. Frontiers in Molecular Biosciences, 5:28. ISSN 2296-889X (Online) (doi:https://doi.org/10.3389/fmolb.2018.00028)

Yap, Ivan K.S., Clayton, T. Andrew, Tang, Huiru, Everett, Jeremy R. ORCID: 0000-0003-1550-4482 , Hanton, Gilles, Provost, Jean-Pierre, Le Net, Jean-Loic, Charuel, Claude, Lindon, John C. and Nicholson, Jeremy K. (2006) An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate. Journal of Proteome Research, 5 (10). pp. 2675-2684. ISSN 1535-3893 (Print), 1535-3907 (Online) (doi:https://doi.org/10.1021/pr0601584)

This list was generated on Thu Mar 28 12:25:04 2024 UTC.