Dobbs, Adrian P. ORCID: 0000-0002-7241-7118 and Dunn, Jonathan (2012) The synthesis and development of 2,5-disubstituted tetrahydrofurans as potential scaffolds for diversity-oriented synthesis. Tetrahedron Letters, 53 (19). pp. 2392-2395. ISSN 0040-4039 (doi:https://doi.org/10.1016/j.tetlet.2012.02.100)

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Abstract

The synthesis of 2,5-disubstituted tetrahydrofurans from donor silylmethylcyclopropanes (without bearing an acceptor function) is described. Their further elaboration via a wide range of synthetic transformations is presented to highlight the potential of this method and the resulting THFs as potential scaffolds for diversity-oriented synthesis.

Item Type:	Article
Uncontrolled Keywords:	silylmethylcyclopropane, donor cyclopropane, 2,5-Disubstituted tetrahydrofuran, Flemming oxidation
Subjects:	R Medicine > RS Pharmacy and materia medica
Faculty / School / Research Centre / Research Group:	Faculty of Engineering & Science > School of Science (SCI)
Related URLs:	Organisation
Last Modified:	21 Oct 2020 22:31
URI:	http://gala.gre.ac.uk/id/eprint/10571

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