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Development of stable polymeric lyophilised wafers for mucosal drug delivery using thermal annealing (DSC, freeze-drying)

Development of stable polymeric lyophilised wafers for mucosal drug delivery using thermal annealing (DSC, freeze-drying)

Kianfar, F., Chowdhry, B., Antonijevic, M. and Boateng, J. (2011) Development of stable polymeric lyophilised wafers for mucosal drug delivery using thermal annealing (DSC, freeze-drying). In: Published Meeting Abstracts [AAPS]. The AAPS Journal, 2011 . American Association of Pharmaceutical Scientists (AAPS), Arlington, VA, USA. ISSN 1550-7416

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Abstract

Purpose: The aim was to develop an optimum freeze-drying cycle incorporating annealing to produce wafers from gels comprising κ-carrageenan, poloxamer 407 and PEG 600 with ibuprofen as a model drug. The effects of the annealing process and ibuprofen concentration on water content and mechanical properties of the wafers were also investigated.

Item Type: Conference Proceedings
Title of Proceedings: Published Meeting Abstracts [AAPS]
Additional Information: [1] This poster was presented at AAPS 2011, i.e. the 2011 AAPS Annual Meeting and Exposition, held from October 23–27, 2011 in Washington Convention Center, Washington, D.C., USA. [2] Poster Number: W4274. [3] Online-only journal.
Uncontrolled Keywords: lyophilised wafers, mucosal drug delivery, carageenan, poloxamer, PEG600, ibuprofen
Subjects: Q Science > QD Chemistry
R Medicine > RS Pharmacy and materia medica
Faculty / Department / Research Group: Faculty of Engineering & Science > Department of Pharmaceutical, Chemical & Environmental Sciences
Related URLs:
Last Modified: 07 Dec 2016 11:55
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
URI: http://gala.gre.ac.uk/id/eprint/7194

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