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Zeaxanthin and ocular health, from bench to bedside

Zeaxanthin and ocular health, from bench to bedside

Manikandan, Ramar, Thiagarajan, Raman, Goutham, Ganesh, Arumugam, Munusamy, Beulaja, Manikandan, Rastrelli, Luca, Skalicka-Woźniak, Krystyna, Habtemariam, Solomon, Orhan, Ilkay Erdogan, Nabavi, Seyed Fazel and Nabavi, Seyed Mohammad (2015) Zeaxanthin and ocular health, from bench to bedside. Fitoterapia, 109. pp. 58-66. ISSN 1873-6971 (doi:10.1016/j.fitote.2015.12.009)

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Abstract

Cataracts, glaucoma, and age-related macular degeneration are known as major ocular problems which cause blindness among the elderly population worldwide. Oxidative stress plays an important role in both the initiation and progression of ocular problems and with respect to this; dietary antioxidants can serve as a therapeutic strategy for the improvement of ocular health. Zeaxanthin is known as one of the most important and common xanthophyll carotenoids, possessing multiple therapeutic effects such as strong antioxidant and pro-oxidant behaviour as well as anti-inflammatory effects. A growing body of literature shows that zeaxanthin mitigates ocular problems and suppresses oxidative stress in the retinal tissues. This paper aims to critically review the available literature regarding the beneficial effects of zeaxanthin on ocular problems with emphasis on its chemistry, bioavailability, and sources.

Item Type: Article
Uncontrolled Keywords: Age-related macular degeneration; Cataract; Ocular problems; Oxidative stress; Zeaxanthin
Subjects: Q Science > QC Physics
Q Science > QD Chemistry
Faculty / Department / Research Group: Faculty of Engineering & Science
Faculty of Engineering & Science > Department of Pharmaceutical, Chemical & Environmental Sciences
Last Modified: 26 Oct 2017 15:36
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
URI: http://gala.gre.ac.uk/id/eprint/17606

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