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The impact of iodoform on the hydration, bioactivity and antimicrobial properties of White Portland Cement

The impact of iodoform on the hydration, bioactivity and antimicrobial properties of White Portland Cement

Coleman, Nichola Jayne and Li, Qiu (2017) The impact of iodoform on the hydration, bioactivity and antimicrobial properties of White Portland Cement. In: 2017 2nd International Conference on Materials Science and Nanotechnology (ICMSNT 2017). MATEC Web of Conferences, 109 (04002). MATEC Web of Conferences. (doi:10.1051/matecconf/201710904002)

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Abstract

Iodoform (CHI3) is a potential radiopacifying agent for use in Portland cement-based root-filling materials. During this study, the impact of 20 wt% iodoform on the hydration and setting of white Portland cement (WPC) was monitored by powder X-ray diffraction, 29Si magic angle spinning nuclear magnetic resonance spectroscopy and Vicat apparatus. The presence of 20 wt% iodoform reduced the initial and final setting times of WPC from 150 to 121 min and 200 to 165 min, respectively. Iodoform had little impact on the products and extent of hydration after 7 days of curing; although, it did cause a reduction in the mean silicate chain length of the C-S-H gel (from 4.11 to 3.47 units). Both iodoform-blended and unblended cement pastes exhibited similar in vitro bioactivity, with the formation of crystalline hydroxyapatite on their surfaces within 1 day of exposure to simulated body fluid. An inhibition zone assay confirmed that WPC possesses intrinsic antimicrobial activity against S. aureus, P. aeruginosa and E. coli, which is significantly enhanced in the presence of iodoform. This study indicates that iodoform may be a suitable radiopacifying agent for Portland cementbased dental restoratives; although, further work is required to determine its long-term stability within the cement matrix.

Item Type: Conference Proceedings
Title of Proceedings: 2017 2nd International Conference on Materials Science and Nanotechnology (ICMSNT 2017)
Additional Information: © The Authors, published by EDP Sciences, 2017. This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Uncontrolled Keywords: Bioactivity, Iodoform, White Portland Cement, Dental cement, Antimicrobial
Subjects: Q Science > QD Chemistry
Faculty / Department / Research Group: Faculty of Engineering & Science
Faculty of Engineering & Science > Department of Pharmaceutical, Chemical & Environmental Sciences
Last Modified: 22 Aug 2017 16:22
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
URI: http://gala.gre.ac.uk/id/eprint/17375

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