Skip navigation

Bone healing following different types of osteotomy: Scanning electron microscopy (SEM) and three-dimensional SEM analyses

Bone healing following different types of osteotomy: Scanning electron microscopy (SEM) and three-dimensional SEM analyses

Blaskovic, Marko, Gabrić, Dragana, Coleman, Nichola, Slipper, Ian J., Mladenov, Mitko and Gjorgievska, Elizabeta (2016) Bone healing following different types of osteotomy: Scanning electron microscopy (SEM) and three-dimensional SEM analyses. Microscopy and Microanalysis, 22 (6). pp. 1170-1178. ISSN 1431-9276 (Print), 1435-8115 (Online) (doi:10.1017/S1431927616011971)

[img]
Preview
PDF (Author Accepted Manuscript)
16207 COLEMAN_Bone_Healing_Osteotomy_2016.pdf - Accepted Version

Download (1MB) | Preview

Abstract

The aim of the present study was to compare dynamics of the bone healing process after different types of osteotomies. In total, 24 Wistar rats were subjected to different types of osteotomy performed with standard steel bur, piezosurgery, contact, and non-contact Erbium:yttrium-aluminum-garnet (Er:YAG) laser ablation. The animals were randomly divided into four groups, to be euthanized immediately after the procedure, or at 1, 2, or 3 weeks after surgery. The obtained bone samples were analyzed by scanning electron microscopy (SEM). Immediately after surgery, there were significant differences in the appearance of the bone defects, with presence of bone fragments and debris after standard steel bur preparation, compared with the clean smooth walls and relatively sharp edges in all other groups. The initial bone formation in defects prepared by piezosurgery was observed to be the most rapid. After 3 weeks, all bone defects were completely restored; although, differences in the healing pattern were noted, with a modest initial delay in healing after laser preparation. The first stage of the bone healing process was delayed when contact and non-contact Er:YAG laser modes were used and accelerated by piezosurgery; however, the results after 3 weeks demonstrated similar restitution of defects in all tested groups.

Item Type: Article
Uncontrolled Keywords: Animal models; Laser; Piezoelectric surgery; Bone healing
Faculty / Department / Research Group: Faculty of Engineering & Science
Faculty of Engineering & Science > Department of Pharmaceutical, Chemical & Environmental Sciences
Last Modified: 15 Aug 2017 12:01
Selected for GREAT 2016: None
Selected for GREAT 2017: GREAT c
Selected for GREAT 2018: None
URI: http://gala.gre.ac.uk/id/eprint/16207

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year

View more statistics