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Evaluation studies of a sensing technique for electrostatic charge polarity of pharmaceutical particulates

Evaluation studies of a sensing technique for electrostatic charge polarity of pharmaceutical particulates

Hussain, Tariq, Deng, Tong ORCID: 0000-0003-4117-4317, Bradley, Michael Samuel, Armour-Chélu, David, Gorman, Terry and Kaialy, Waseem (2016) Evaluation studies of a sensing technique for electrostatic charge polarity of pharmaceutical particulates. IET Science Measurement and Technology, 10 (5). pp. 442-448. ISSN 1751-8822 (Print), 1751-8830 (Online) (doi:https://doi.org/10.1049/iet-smt.2015.0194)

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Abstract

Electrostatic charge due to inter-particle and particle-wall contacts may generate significant hazards during the processing of particulates within the pharmaceutical industry. Although charge behaviour of particulates is erratic and not easy to predict, it would be desirable to characterise the tendency of tribocharging prior to manufacturing. The work reported in this paper concentrates on a new and novel techniques for the detection of the active ingredient and excipient in a bipolar material. Three different case studies are presented for demonstration of the applicability of the method in different practical situations. Work confirmed through an experimental rig set-up indicates that materials that accumulate opposite charge via contact and rubbing can be detected from their charge sign as well as their relative magnitude. The results reported clearly demonstrated that the developed method for charge characterisation is a useful tool to understand how the charges are distributed in a population of particles showing a number of advantages over conventional methods.

Item Type: Article
Additional Information: This paper is a postprint of a paper submitted to and accepted for publication in IET Science Measurement and Technology and is subject to Institution of Engineering and Technology Copyright. The copy of record is available at IET Digital Library.
Uncontrolled Keywords: Charge measurement; Electrostatic charging
Subjects: T Technology > TA Engineering (General). Civil engineering (General)
Faculty / School / Research Centre / Research Group: Faculty of Engineering & Science
Faculty of Engineering & Science > School of Engineering (ENG)
Last Modified: 13 Aug 2020 17:35
URI: http://gala.gre.ac.uk/id/eprint/14724

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