Skip navigation

A multi-ingredient containing carbohydrate, proteins L-glutamine and L-carnitine attenuates fatigue perception with no effect on performance, muscle damage or immunity in soccer players

A multi-ingredient containing carbohydrate, proteins L-glutamine and L-carnitine attenuates fatigue perception with no effect on performance, muscle damage or immunity in soccer players

Naclerio, Fernando ORCID: 0000-0001-7405-4894, Larumbe-Zabala, Eneko, Cooper, Robert, Allgrove, Judith and Earnest, Conrad P. (2015) A multi-ingredient containing carbohydrate, proteins L-glutamine and L-carnitine attenuates fatigue perception with no effect on performance, muscle damage or immunity in soccer players. PLoS ONE, 10 (4):e0125188. pp. 1-17. ISSN 1932-6203 (Print), 1932-6203 (Online) (doi:10.1371/journal.pone.0125188)

[img]
Preview
PDF (Publisher's PDF - GOLD OA)
13635_NACLERIO_COOPER_PLOSONE_(Gold_OA_27April2015).pdf - Published Version
Available under License Creative Commons Attribution.

Download (598kB)
[img] PDF (Email of Acceptance)
13635_NACLERIO_COOPER_PLOSONE_(Gold_OA_acceptance_email_30March2015_held_for_compliance).pdf - Additional Metadata
Restricted to Repository staff only

Download (101kB)
[img] PDF (Author Accepted Manuscript)
13635_NACLERIO_COOPER_PLOSONE_(Gold_OA_AAM_accepted_March2015_and_held_for_compliance).pdf - Accepted Version
Restricted to Repository staff only

Download (400kB)

Abstract

We investigated the effects of ingesting a multi-ingredient (53g carbohydrate, 14.5g whey protein, 5g glutamine, 1.5g L-carnitine-L-tartrate) supplement, carbohydrate only, or placebo on intermittent performance, perception of fatigue, immunity, and functional and metabolic markers of recovery. Sixteen amateur soccer players ingested their respective treatments before, during and after performing a 90-min intermittent repeated sprint test. Primary outcomes included time for a 90-min intermittent repeated sprint test (IRS) followed by eleven 15 m sprints. Measurements included creatine kinase, myoglobin, interleukine-6, Neutrophil; Lymphocytes and Monocyte before (pre), immediately after (post), 1h and 24h after exercise testing period. Overall, time for the IRS and 15 m sprints was not different between treatments. However, the perception of fatigue was attenuated (P<0.001) for the multi-ingredient (15.9±1.4) vs. placebo (17.8±1.4) but not for the carbohydrate (17.0±1.9) condition. Several changes in immune/inflammatory indices were noted as creatine kinase peaked at 24h while Interleukin-6 and myoglobin increased both immediately after and at 1h compared with baseline (P<0.05) for all three conditions. However, Myoglobin (P<0.05) was lower 1h post-exercise for the multi-ingredient (241.8±142.6 ng·ml-1) and CHO (265.4±187.8 ng·ml-1) vs. placebo (518.6±255.2 ng·ml-1). Carbohydrate also elicited lower neutrophil concentrations vs. multi-ingredient (3.9±1.5 109/L vs. 4.9±1.8 109/L, P = 0.016) and a reduced (P<0.05) monocytes count (0.36±0.09 109/L) compared to both multi-ingredient (0.42±0.09 109/L) and placebo (0.42±0.12 109/L). In conclusion, multi-ingredient and carbohydrate supplements did not improve intermittent performance, inflammatory or immune function. However, both treatments did attenuate serum myoglobin, while only carbohydrate blunted post-exercise leukocytosis.

Item Type: Article
Additional Information: [1] Copyright: (c) 2015 Naclerio et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. [2] Dataset. Supporting information including all data collected during the study. doi:10.1371/journal.pone.0125188.s001 (XLSX). [3] Acknowledgement (funding): Maxinutrition GlaxoSmithKline provided joint funding for the development of the project. No additional external funding was received for this study. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Uncontrolled Keywords: sports, carbohydrates, fatigue, material fatigue, neutrophils, ingestion, monocytes, blood, soccer players, immunity, muscle damage
Subjects: Q Science > QP Physiology
R Medicine > R Medicine (General)
Faculty / Department / Research Group: Faculty of Engineering & Science
Faculty of Engineering & Science > Centre for Science and Medicine in Sport and Exercise
Faculty of Engineering & Science > Department of Life & Sports Sciences
Related URLs:
Last Modified: 14 Nov 2017 10:37
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
URI: http://gala.gre.ac.uk/id/eprint/13635

Actions (login required)

View Item View Item

Downloads

Downloads per month over past year

View more statistics