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Curcumin and liver health: From chemistry to medicine

Curcumin and liver health: From chemistry to medicine

Nabavi, Seyed Fazel, Daglia, Maria, Habtemariam, Solomon, Nabavi, Seyed Mohammad and Moghaddam, Akbar Hajizadeh (2014) Curcumin and liver health: From chemistry to medicine. Comprehensive Reviews in Food Science and Food Safety, 12 (1). pp. 62-67. ISSN 1541-4337 (Print), 1541-4337 (Online) (doi:10.1111/1541-4337.12047)

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Abstract

Curcumin, the natural yellow-colored active principle, also called turmeric yellow, extracted from the perennial herb Curcuma longa L., has potent biological and pharmacological properties such as antioxidant, anti-inflammatory, antifungal, antibacterial, anti-ischemic, antitumor, and anticancer actions. The molecular mechanism of the hepatoprotective action of curcumin is due to its antioxidant properties and inhibitory activity against nuclear factor (NF)-κB that regulates different proinflammatory and profibrotic cytokines. Overall, scientific reports demonstrate that curcumin has high therapeutic ability for treating hepatic disorders. Here is a systematic discussion of the hepatoprotective activity of curcumin and its possible mechanisms of actions.

Item Type: Article
Uncontrolled Keywords: Antioxidant, Curcumin, Hepatic disorders, Nuclear factor-kB, Turmeric
Faculty / Department / Research Group: Faculty of Engineering & Science > Department of Pharmaceutical, Chemical & Environmental Sciences
Last Modified: 17 Oct 2016 09:13
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
URI: http://gala.gre.ac.uk/id/eprint/13419

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