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[Letter] The aza-silyl-prins reaction: A novel method for the synthesis of trans-2,6-tetrahydropyridines

[Letter] The aza-silyl-prins reaction: A novel method for the synthesis of trans-2,6-tetrahydropyridines

Dobbs, Adrian P., Guesné, Sebastien J.J., Hursthouse, Michael B. and Coles, Simon J. (2003) [Letter] The aza-silyl-prins reaction: A novel method for the synthesis of trans-2,6-tetrahydropyridines. Synlett (11). pp. 1740-1742. ISSN 0936-5214 (Print), 1437-2096 (Online) (doi:10.1055/s-2003-41434)

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Abstract

Reaction of 4-trimethylsilyl-3-butenyl-1-amines with aldehydes under mild Lewis acid conditions gives substituted tetrahydropyridines in excellent yields and with excellent trans diastereoselectivity.

Item Type: Article
Uncontrolled Keywords: Prins reaction, aldehydes, indium trichloride
Subjects: Q Science > QD Chemistry
Faculty / Department / Research Group: Faculty of Engineering & Science > Department of Pharmaceutical, Chemical & Environmental Sciences
Related URLs:
Last Modified: 17 Oct 2016 09:12
Selected for GREAT 2016: None
Selected for GREAT 2017: None
Selected for GREAT 2018: None
URI: http://gala.gre.ac.uk/id/eprint/10585

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